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- Raghu, Chantel; Ekena, Joanne; Cullen, John M.; Webb, Craig B.; Trepanier, Lauren A.
- Journal of veterinary internal medicine 2018 v.32 no.3 pp. 1009-1018
- C-reactive protein; alanine transaminase; aspartate transaminase; biomarkers; biopsy; blood serum; chemokine CCL2; dogs; fibrosis; histopathology; humans; interleukin-6; laparoscopy; laparotomy; ligands; liver; liver cirrhosis; medicine; monitoring
- ... BACKGROUND: Serum interleukin 6 (IL‐6), chemokine ligand 2 (CCL2), C‐reactive protein (CRP), and the ratio of aspartate transaminase to alanine transaminase (AST:ALT) have been correlated with fibrosis and necroinflammatory activity in humans with various hepatopathies. HYPOTHESIS/OBJECTIVES: To determine whether increases in serum IL‐6, CCL2, CRP, or AST:ALT were associated with moderate to sever ...