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- Foster, D. M.; Sylvester, H. J.; Papich, M. G.
- Journal of veterinary pharmacology and therapeutics 2017 v.40 no.6 pp. e45
- enrofloxacin, etc ; antibiotics; bovine respiratory disease; calves; ciprofloxacin; drugs; epithelium; high performance liquid chromatography; metabolites; minimum inhibitory concentration; pathogens; pharmacokinetics; Show all 12 Subjects
- ... Antibiotic distribution to interstitial fluid (ISF) and pulmonary epithelial fluid (PELF) was measured and compared to plasma drug concentrations in eight healthy calves. Enrofloxacin (Baytril® 100) was administered at a dose of 12.5 mg/kg subcutaneously (SC), and tilmicosin (Micotil® 300) was administered at a dose of 20 mg/kg SC. PELF, sampled by two different methods—bronchoalveolar lavage (BAL ...