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- Morrison, Juliet; Josset, Laurence; Tchitchek, Nicolas; Chang, Jean; Belser, Jessica A.; Swayne, David E.; Pantin-Jackwood, Mary J.; Tumpey, Terrence M.; Katze, Michael G.
- Journal of virology 2014 v.88 no.18 pp. 10556-10568
- Food and Drug Administration; Influenza A virus; animal disease models; avian influenza; cytokines; drugs; genes; host-pathogen relationships; lipid metabolism; mice; pandemic; pathogenesis; pathogenicity; transcription (genetics); transcriptome; transcriptomics; virulent strains; viruses
- ... Modulating the host response is a promising approach to treating influenza, caused by a virus whose pathogenesis is determined in part by the reaction it elicits within the host. Though the pathogenicity of emerging H7N9 influenza virus in several animal models has been reported, these studies have not included a detailed characterization of the host response following infection. Therefore, we cha ...
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