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You searched for: Journal Laboratory animals Remove constraint Journal: Laboratory animals Publication Year 1994 Remove constraint Publication Year: 1994 Source 1994 v.28 no.1 Remove constraint Source: 1994 v.28 no.1
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1. Anew method of faeces collection in the pig

Author:
van Kleef, D. J.; Deuring, K.; van Leeuwen, P.
Source:
Laboratory animals 1994 v.28 no.1 pp. 78-79
ISSN:
1758-1117
Subject:
feces; laboratory animals; swine
Abstract:
... A new faeces collection method for pigs has been developed which allows collection of faeces into a plastic bag. This new method greatly reduces faecal losses and thereby permits virtually complete collection of faecal material. The method can be applied easily and causes less discomfort to the animals than previous methods. ...
DOI:
10.1258/002367794781065942

2. Behaviour of nucleolar organizer regions in the different Wistar rat liver lobes

Author:
Garcia-Moreno, Luis; Vallejo, Guillwemo; Arias, Jorge L.; Aller, Mary-Angeles; Lorente, Laureano; Arias, Jaime
Source:
Laboratory animals 1994 v.28 no.1 pp. 50-54
ISSN:
1758-1117
Subject:
hepatectomy; laboratory animals; liver; males; protein synthesis; rats
Abstract:
... The area and number of silver-nucleolar organizer regions (Ag-NORs) in the hepatic lobes were determined in 3 male Wistar rats. There was a statistically significant increase in the percentage of Ag-NORs per nucleus in the right lateral and caudate lobe in relation to the left lateral and middle lobes. The area and number of Ag-NORs are greater in the caudate and right lateral lobes in relation to ...
DOI:
10.1258/002367794781065780

3. Bilateral complex odontoma in a Swiss (CD-1) male mouse

Author:
Dayan, Dan; Waner, Trevor; Harmelin, Alon; Nyska, Abraham
Source:
Laboratory animals 1994 v.28 no.1 pp. 90-92
ISSN:
1758-1117
Subject:
laboratory animals; males; mice; neoplasms; teeth
Abstract:
... The present report describes the morphological features of a spontaneous, bilateral, complex odontoma of the incisor teeth in an 87-week-old male Swiss mouse (Crl: CD-1(ICR)BR). This report constitutes the second report of an odontogenic tumour in a Swiss mouse and the first describing a bilateral complex odontoma in this strain of mouse. The report emphasizes the importance of thoroughly examinin ...
DOI:
10.1258/002367794781065898

4. Calcified foci at the junction between adrenal cortex and medulla of rhesus monkeys

Author:
Kast, Alexander; Peil, Hubertus; Weisse, Ingo
Source:
Laboratory animals 1994 v.28 no.1 pp. 80-89
ISSN:
1758-1117
Subject:
Macaca fascicularis; Macaca mulatta; adrenal cortex; adrenal medulla; apoptosis; body weight; cortex; diet; females; laboratory animals; males; mineralization; monkeys; surveys; toxicity testing
Abstract:
... The occurrence of calcified foci at the junction of adrenal medulla and cortex in monkeys obtained from toxicity studies during a 10-year period is reported. The survey included reinvestigated adrenal samples from 274 male and 270 female rhesus monkeys and 52 male and 52 female cynomolgus monkeys. The incidence of calcified foci was 46% in male and 45% in female rhesus monkeys, and 6% in male cyno ...
DOI:
10.1258/002367794781065834

5. Changes with age of mammary glands in male and female soft-furred rat, Millardia meltada, in relation to prolactin and testosterone

Author:
Nagasawa, H.; Mori, T.; Sakamoto, S.; Sassa, S.; Yamamuro, Y.; Sensui, N.; Tajima, M.; Goto, Y.
Source:
Laboratory animals 1994 v.28 no.1 pp. 35-43
ISSN:
1758-1117
Subject:
DNA; DNA replication; animal ovaries; blood serum; enzyme activity; females; histology; laboratory animals; males; mammary glands; mammary neoplasms (animal); mice; pigments; prolactin; rats; testes; testosterone; thymidine kinase; thymidylate synthase; uterus
Abstract:
... The soft-furred rat, millardia (Millardia meltada), is characterized by the development of androgen-dependent mammary tumours only in males. The age-related changes of the activities of thymidylate synthetase (TS) and thymidine kinase (TK), which contribute to DNA synthesis through de novo and salvage pathways, respectively, and structure in the mammary glands were studied in both males and female ...
DOI:
10.1258/002367794781065690

6. Comparison of indirect haemagglutination test, gel-diffusion precipitin test, and enzyme-linked immunosorbent assay for detection of serum antibodies to Pasteurella multocida in naturally and experimentally infected rabbits

Author:
Kawamoto, Eiichi; Sawada, Takuo; Sato, Toru; Suzuki, Kiyoshi; Maruyama, Tsutomu
Source:
Laboratory animals 1994 v.28 no.1 pp. 19-25
ISSN:
1758-1117
Subject:
Pasteurella multocida; antibodies; blood serum; enzyme-linked immunosorbent assay; hemagglutination tests; laboratory animals; nose; pasteurellosis; precipitin tests; rabbits; serodiagnosis
Abstract:
... Enzyme-linked immunosorbent assay (ELISA), gel-diffusion precipitin test (GDPT), and indirect haem agglutination test (IHAT) were evaluated for the detection of antibodies to Pasteurella multocida in both naturally and experimentally infected rabbits. A total of 285 rabbit serum samples from 7 rabbit colonies were tested by ELISA, GDPT, and IHAT, and nasal cultures were taken coincidentally to use ...
DOI:
10.1258/002367794781065915

7. Detection of rodent RNA viruses by polymerase chain reaction

Author:
Taylor, K.; Copley, C. G.
Source:
Laboratory animals 1994 v.28 no.1 pp. 31-34
ISSN:
1758-1117
Subject:
Murine respirovirus; Rat coronavirus; polymerase chain reaction; laboratory animals; Murine hepatitis virus; rats
Abstract:
... Assays for rodent coronaviruses (mouse hepatitis virus and rat corona/sialodacryoadenitis virus) and a rodent paramyxovirus (Sendai virus) based on the polymerase chain reaction are described. ...
DOI:
10.1258/002367794781065861

8. Diagnosis of Kilham rat virus using PCR

Author:
Taylor, K.; Copley, C. G.
Source:
Laboratory animals 1994 v.28 no.1 pp. 26-30
ISSN:
1758-1117
Subject:
Rodent protoparvovirus 1; antibodies; diagnostic techniques; genetic code; immunoglobulin G; laboratory animals; polymerase chain reaction; rodents; serodiagnosis; serology; signs and symptoms (animals and humans); tissue culture
Abstract:
... The exclusive use of serology, namely immunofluorescent antibody (IFA), for the diagnosis of rodent parvovirus infection is limited to detecting IgG antibodies which develop some time after the appearance of clinical symptoms, whilst conventional viral isolation, using tissue culture, is both expensive and time consuming. Polymerase chain reaction (PCR) as a diagnostic method has the potential to ...
DOI:
10.1258/002367794781065807

9. Glycated albumin: a marker of glycaemic status in rats with experimental diabetes

Author:
Neuman, R. Glenn; Hud, Elizabeth; Cohen, Margo P.
Source:
Laboratory animals 1994 v.28 no.1 pp. 63-69
ISSN:
1758-1117
Subject:
albumins; animal disease models; blood glucose; diabetes; dose response; epitopes; fasting; immunoassays; laboratory animals; monoclonal antibodies; polyclonal antibodies; rats; streptozotocin
Abstract:
... Monoclonal antibodies that specifically recognize non-enzymatically glycated epitopes residing in albumin were used to measure levels of glycated albumin in the plasma of control and streptozotocin diabetic rats. Standard or sample was incubated with monoclonal antibody immobilized onto preactivated tubes, and binding was detected with enzyme-conjugated polyclonal antibody to rat albumin and subst ...
DOI:
10.1258/002367794781065663

10. Guidelines for the welfare of animals in rodent protection tests: A Report from the Rodent Protection Test Working Party

Author:
Acred, P.; Hennessey, T. D.; MacArthur-Clark, J. A.; Merrikin, D. J.; Ryan, D. M.; Smulders, H. C.; Troke, P. F.; Wilson, R. G.; Straughan, D. W.
Source:
Laboratory animals 1994 v.28 no.1 pp. 13-18
ISSN:
1758-1117
Subject:
animal use reduction; antifungal agents; death; euthanasia; guidelines; laboratory animals; rodents; signs and symptoms (animals and humans)
Abstract:
... The rodent protection test (RPT) is used in antimicrobial research to confirm the in vivo efficacy of novel antibacterial, antiviral and antifungal agents. The RPT may involve lethal infection and thus has the potential to cause significant suffering. These Guidelines recommend refinements to the RPT which reduce animal use to a minimum and suggest cardinal clinical signs which act as predictors o ...
DOI:
10.1258/002367794781065870

11. Maternal age, reproduction and chromosomal aberrations in Wistar derived rats

Author:
Niggeschulze, Adolf; Kast, Alexander
Source:
Laboratory animals 1994 v.28 no.1 pp. 55-62
ISSN:
1758-1117
Subject:
abnormal development; bone marrow; chromosome aberrations; copulation; embryotoxicity; genotoxicity; laboratory animals; males; pregnancy rate; rats; resorption; risk assessment; teratogenicity; virgin females; women
Abstract:
... The fertility of rats ranges from one to 18 months. In standard teratogenicity testing young, mature females are used which may not reflect the situation in women above 35 years old. Reproduction among different age groups of Wistar ats (strain Chbb : THOM) was compared at 3, 6, 9, 12, 15 and 18 months. At least 20 virgin females were inseminated per age group. The copulation rate did not differ b ...
DOI:
10.1258/002367794781065717

12. Pregnancy dependence of mammary tumours in DDD mice congenic for Mtv-2, DDD/1-Mtv-2/Mtv-2

Author:
Sayama, Kazutoshi; Kaneko, Tetsuya; Matsuzawa, Akio
Source:
Laboratory animals 1994 v.28 no.1 pp. 44-49
ISSN:
1758-1117
Subject:
DDD (pesticide); breeding; females; laboratory animals; mammary neoplasms (animal); mice; models; pregnancy
Abstract:
... Mammary tumours developed in 110 (95.7%) of 115 DDD/1-Mtv-2/Mtv-2 (DDD/1-Mtv-2) and 24 (47·1%) of 51 DDD/1fDDD/1-Mtv-2 (DDD/1fMtv-2) force-bred female mice during a one-year period. The mean tumour age±SE was 220±7 and 269±7 days, respectively. These tumours were examined for responsiveness to pregnancies by comparing their growth after transplantation between virgin and breeding recipients. Of 73 ...
DOI:
10.1258/002367794781065889

13. The use of etorphine/methotrimeprazine and midazolam as an anaesthetic technique in laboratory rats and mice

Author:
Whelan, G.; Flecknell, P. A.
Source:
Laboratory animals 1994 v.28 no.1 pp. 70-77
ISSN:
1758-1117
Subject:
acidosis; anesthesia; blood gases; etorphine; fentanyl; hypercapnia; hypoxia; laboratory animals; mice; muscles; oxygen; rats
Abstract:
... The results of a preliminary evaluation of etorphine/methotrimeprazine ('Small Animal Immobilon') and midazolam in rats and mice are reported, and this regimen is compared to fentanyl/fluanisone/midazolam in mice. In rats, a surgical plane of anaesthesia with good muscle relaxation was produced, but blood gas analysis showed the presence of severe hypoxia, hypercapnia and acidosis. In mice etorphi ...
DOI:
10.1258/002367794781065735