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You searched for: Journal Laboratory animals Remove constraint Journal: Laboratory animals Publication Year 1988 Remove constraint Publication Year: 1988 Source 1988 v.22 no.1 Remove constraint Source: 1988 v.22 no.1
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1. Allelic profile at 37 biochemical loci of two inbred strains of the house mouse derived from wild Mus musculus musculus

Author:
Von Deimlingi, O. H.; Forejt, J.; Wienker, T. F.
Source:
Laboratory animals 1988 v.22 no.1 pp. 61-66
ISSN:
1758-1117
Subject:
Mus musculus; alleles; allozymes; genetic distance; genetic relationships; laboratory animals; loci
Abstract:
... Two newly established inbred strains derived from Mus musculus musculus, designated PWD/Ph (F29) and PWK/Ph (F33), were examined for their alleles at 37 biochemical loci located on 12 different chromosomes. The allelic pattern showed characteristic differences from those observed in common inbred strains. The genetic distance D between PWK/Ph and PWD/Ph was 0·027, whereas the corresponding values ...
DOI:
10.1258/002367788780746610

2. Alloxan-induced diabetes mellitus in pregnant sheep and chronic fetal catheterization

Author:
Lips, J. P.; Jongsma, H. W.; Eskes, T. K. A. B.
Source:
Laboratory animals 1988 v.22 no.1 pp. 16-22
ISSN:
1758-1117
Subject:
Texel; alloxan; amniotic fluid; anesthesia; blood gases; blood glucose; carotid arteries; catheters; creatinine; diabetes mellitus; electrodes; electroencephalography; electromyography; ewes; fetus; glucose; insulin; jugular vein; laboratory animals; pregnancy; standard deviation; urea
Abstract:
... 25 female sheep of the Texel breed were made hyperglycaemic by administration of alloxan monohydrate (ALX) in early pregnancy and 15 ewes served as controls. Average venous glucose levels (mean ± standard deviation) increased from 3·5 ± 0·2 to 14·0 ± 1·8 mmol/l. All hyperglycaemic sheep were treated with long-acting insulin in doses adjusted individually (0·2-1·0 U/kg per day) to keep glucose leve ...
DOI:
10.1258/002367788780746638

3. Altered clinical and histological features of male MM mouse pyelonephritis associated with a change in its microbiology

Author:
Taylor, D. M.; Fraser, H.; Bruce, M. E.
Source:
Laboratory animals 1988 v.22 no.1 pp. 35-45
ISSN:
1758-1117
Subject:
amyloidosis; histology; kidneys; laboratory animals; males; mice; microbiology; necropsy; pyelonephritis
Abstract:
... Radical changes in the clinical, microbiological and histological features of spontaneous pyelonephritis in MM male mice occurred when they were transferred to a new environment after Caesarian derivation. Although the incidence of pyelonephritis remained the same, the survival age was increased. The renal histology indicated a shift to a more chronic form of pyelonephritis with renal amyloidosis ...
DOI:
10.1258/002367788780746575

4. Aseptic necrosis of bone in ICR mice

Author:
Yamasaki, K.; Itakura, C.
Source:
Laboratory animals 1988 v.22 no.1 pp. 51-53
ISSN:
1758-1117
Subject:
blood; cartilage; epiphyses; histology; laboratory animals; mice; osteoarthritis; osteonecrosis; tibia
Abstract:
... Aseptic bone necrosis was observed in the tibia of 23 ICR mice. Histological changes were characterized by a loss of marrow tissue with proliferation of connective tissue and bone necrosis with empty osteocytic lacunae. Focal necrosis was confined beneath the articular cartilage. Extensive necrosis was present in half or all of the epiphysis. Massive necrosis was noted in the diaphysis of one anim ...
DOI:
10.1258/002367788780746601

5. A shift from acute to chronic spontaneous pyelonephritis in male MM mice associated with a change in the causal micro-organisms

Author:
Taylor, D. M.
Source:
Laboratory animals 1988 v.22 no.1 pp. 27-34
ISSN:
1758-1117
Subject:
Enterococcus faecalis; Pasteurella pneumotropica; Proteus mirabilis; blood; culture media; feces; humans; laboratory animals; males; mice; microorganisms; pathogenicity; pyelonephritis; urine
Abstract:
... Proteus mirabilis was the predominant cause of acute diabetes-associated pyelonephritis occurring spontaneously in male MM mice until they were segregated in a new environment. Thereafter Pasteurella pneumotropica and Streptococcus faecalis emerged collectively as the most common causal organisms, the pyelonephritis became more chronic and Proteus mirabilis isolates from faeces and urine produced ...
DOI:
10.1258/002367788780746557

6. A simple method for prevention of coprophagy in the mouse

Author:
Ebino, K. Y.; Yoshinaga, K.; Saito, T. R.; Takahashi, K. W.
Source:
Laboratory animals 1988 v.22 no.1 pp. 1-4
ISSN:
1758-1117
Subject:
anus; bottles; cages; coprophagy; feces; floors; head; laboratory animals; mice; nutrition; polyethylene
Abstract:
... A series of studies of coprophagy in mice has been conducted from the viewpoints of behaviour and nutrition. Since it was necessary to prevent coprophagy to investigate its significance, an attempt was made to devise a re-strainer. A polyethylene bottle was cut and fixed to the mouse so as to prevent its head from reaching its anus when faeces were excreted. The animals were also housed in cages w ...
DOI:
10.1258/002367788780746548

7. A 2 year follow-up of effects of biotechniques on reproduction in the domestic rabbit, Oryctolagus cuniculus

Author:
Fischer, B.; Meuser-Odenkirchen, G.
Source:
Laboratory animals 1988 v.22 no.1 pp. 5-15
ISSN:
1758-1117
Subject:
Oryctolagus cuniculus; artificial insemination; embryo (animal); embryonic mortality; females; follicle-stimulating hormone; human chorionic gonadotropin; intravenous injection; laboratory animals; natural mating; ovulation; rabbits
Abstract:
... Routinely employed reproductive techniques such as gonadotropin treatment (0·3 mg follicle-stimulating hormone (FSH) subcutaneously twice daily for three consecutive days) followed by natural mating or artificial insemination as well as induction of ovulation by human chorionic gonadotropin (hCG) (75 i.u. hCG intravenously) were analysed in the rabbit after 2 years of consecutive experiments. 85% ...
DOI:
10.1258/002367788780746629

8. Dermal cryptococcosis in a guineapig

Author:
Van Herck, H.; Van Den Ingh, Th. S. G. A. M.; Van Der Hage, M. H.; Zwart, P.
Source:
Laboratory animals 1988 v.22 no.1 pp. 88-91
ISSN:
1758-1117
Subject:
cryptococcosis; histology; laboratory animals; nose; therapeutics
Abstract:
... A case of cryptococcosis in a guineapig with lesions confined to the dorsum of the nose is described. Results of clinical, postmortem and histological examination are discussed. The diagnostic and therapeutic possibilities and problems of cryptococcosis are mentioned. ...
DOI:
10.1258/002367788780746494

9. Effects of repeated blood samplings on locomotor activity, evasion and wheel-running activity in mice

Author:
Pfeil, R.
Source:
Laboratory animals 1988 v.22 no.1 pp. 46-50
ISSN:
1758-1117
Subject:
blood sampling; erythrocyte count; hematocrit; hemoglobin; hemorrhage; laboratory animals; locomotion; males; mice
Abstract:
... The effects of serial blood sampling on nocturnal locomotor activity, evasion, wheel-running activity and body mass were studied in male NMRI mice aged 7-8 weeks. The erythrocyte count, haematocrit and haemoglobin concentration at the beginning and end of the study showed no difference in group 1 (two samples per week, 0·08 ml each) while there was a significant decrease in the group 2 values (thr ...
DOI:
10.1258/002367788780746520

10. Embryonic death in pregnant rats owing to intercurrent infection with Sendai virus and Pasteurella pneumotropica

Author:
Carthew, P.; Aldred, P.
Source:
Laboratory animals 1988 v.22 no.1 pp. 92-97
ISSN:
1758-1117
Subject:
Pasteurella pneumotropica; Sendai virus; embryo (animal); embryogenesis; embryonic mortality; fetus; giant cells; laboratory animals; lungs; microorganisms; pregnancy; rats; resorption
Abstract:
... During an outbreak of Sendai virus infection in a colony of rats used for embryo production, severe lung lesions due to secondary colonization of the rat lungs with Pasteurella pneumotropica were noted. The effect on pregnancy was to cause embryonic death and resorption, leaving a deciduoma with trophoblastic giant cells as the only embryonic remnants. Up to 30% of fetuses in each pregnant animal ...
DOI:
10.1258/002367788780746566

11. Infantile disease with microvesicular fatty infiltration of viscera spontaneously occurring in the C3H-H-2° strain of mouse with similarities to Reye's syndrome

Author:
Koizumi, T.; Nikaidoi, H.; Hayakawa, J.; Nonomura, A.; Yoneda, T.
Source:
Laboratory animals 1988 v.22 no.1 pp. 83-87
ISSN:
1758-1117
Subject:
animal organs; children; histopathology; laboratory animals; mice
Abstract:
... The clinical, biochemical and histopathological findings of an infantile disease occurring in the C3H-H-2° strain of mice, which has similarities with Reye's syndrome in children, is described. ...
DOI:
10.1258/002367788780746511

12. Megaoesophagus in ICRC mice

Author:
Randelia, H. P.; Lalitha, V. S.
Source:
Laboratory animals 1988 v.22 no.1 pp. 23-26
ISSN:
1758-1117
Subject:
genetics; histology; laboratory animals; mice
Abstract:
... The occurrence of megaoesophagus in ICRC/HiCri mice afforded opportunities to study the genetics and histology of this condition. The anomaly was found to be inherited as a recessive character. Histology indicated abnormality in the myenteric plexus. ...
DOI:
10.1258/002367788780746502

13. Morphology of the terminal bronchiolar region of common laboratory mammals

Author:
Bal, H. S.; Ghoshal, N. G.
Source:
Laboratory animals 1988 v.22 no.1 pp. 76-82
ISSN:
1758-1117
Subject:
bronchioles; gerbils; hamsters; laboratory mammals; light microscopy; mice; rabbits; rats
Abstract:
... The histomorphology of the terminal bronchiolar region of the mouse, rat, hamster, guineapig, gerbil and rabbit was studied. Although some general structural similarities existed in the progressive intrapulmonary branching pattern of the airway tree between species, there were conflicting accounts in the literature about the presence of the respiratory bronchioles in common laboratory mammals. In ...
DOI:
10.1258/002367788780746539

14. The behaviour of chickens, mice and rats during euthanasia with chloroform, carbon dioxide and ether

Author:
Blackshaw, J. K.; Fenwick, D. C.; Beattie, A. W.; Allan, D. J.
Source:
Laboratory animals 1988 v.22 no.1 pp. 67-75
ISSN:
1758-1117
Subject:
carbon dioxide; chickens; chloroform; death; euthanasia; laboratory animals; mice; rats
Abstract:
... Euthanasia of chickens, young and mature rats, and mice was assessed using chloroform, carbon dioxide and ether. Behavioural patterns were recorded to give some indication of the stress involved. Carbon dioxide induced collapse faster (11·2 ± 0·4 s) than chloroform(18·9 ± 0·4 s) or ether (> 60 s). With regard to the time taken to death, in carbon dioxide mice had the shortest time (48 ± 10 s) and ...
DOI:
10.1258/002367788780746674

15. The initiation and maintenance of a colony of coccidia-free wood mice (Apodemus sylvaticus)

Author:
Higgs, S.; Nowell, F.; Ibrahim, S. A. M.
Source:
Laboratory animals 1988 v.22 no.1 pp. 54-60
ISSN:
1758-1117
Subject:
Apodemus sylvaticus; Eimeria; breeding; enzootic diseases; laboratory animals; laboratory experimentation
Abstract:
... Wood mice from a population showing enzootic infection with Eimeria were trapped and bred under laboratory conditions. The maintenance regime, which freed the animals from coccidia, and the breeding procedures used over several generations are described and discussed. ...
DOI:
10.1258/002367788780746665