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- Teilmann, A C; Kalliokoski, Otto; Sørensen, Dorte B; Hau, Jann; Abelson, Klas S P
- Laboratory animals 2014 v.48 no.4 pp. 278-291
- automation; blood; blood sampling; body weight; carotid arteries; catheters; caudal vein; corticosterone; laboratory animals; males; metabolites; mice; tail
- ... Facial vein (cheek blood) and caudal vein (tail blood) phlebotomy are two commonly used techniques for obtaining blood samples from laboratory mice, while automated blood sampling through a permanent catheter is a relatively new technique in mice. The present study compared physiological parameters, glucocorticoid dynamics as well as the behavior of mice sampled repeatedly for 24 h by cheek blood, ...
- Wedel, Johannes; Weij, Michel; Oosten, Annemieke Smit-van; Hillebrands, Jan-Luuk
- Laboratory animals 2014 v.48 no.4 pp. 338-341
- bioavailability; catheters; intravenous injection; jugular vein; laboratory animals; physical activity; pumps; rats; risk; weight gain
- ... Subcutaneous osmotic pump implantation connected to a venous catheter is a well-established method for delivering compounds intravenously for an intermediate duration (approximately two weeks). When prolonged release is desired (approximately four weeks) reduced flow rate is needed with a similar pump volume. With a fixed intra-pump compound concentration, reduced flow rate results in unwanted red ...