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- Chen, Yang, et al. Show all 11 Authors
- Life sciences 2016 v.147 pp. 97-102
- blood serum; carbon tetrachloride; enzyme-linked immunosorbent assay; histology; hospitals; humans; insulin; insulin-like growth factor I; insulin-like growth factor I receptor; intraperitoneal injection; liver; liver cirrhosis; liver neoplasms; mice; models; parenchyma (animal tissue); patients; signal transduction; staining; tau-protein kinase; tissue banks; China
- ... Liver cirrhosis is the common pathological histology manifest among a number of chronic liver diseases and liver cancer. Circulating levels of insulin growth factor-1 (IGF-1) have been recently linked to liver cirrhosis and the development of liver cancer. Herein, we hypothesized that IGF-1R overexpression combining the activation of GSK-3β and FOXO3a were involved in the development of human and ...