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- Jian, Yating, et al. Show all 12 Authors
- Life sciences 2019 v.221 pp. 259-266
- Alzheimer disease; animal models; apoptosis; cell viability; cognitive disorders; cytotoxicity; messenger RNA; protective effect; protein content; reactive oxygen species; response elements; signal transduction; superoxide dismutase
- ... Edaravone potentially alleviates cognitive deficits in a mouse model of Alzheimer's disease (AD). However, the mechanism of edaravone in suppressing AD progression remains unclear. We aim to investigate the mechanism of edaravone in suppressing oxidative stress-mediated AD progression in vitro.Human neuroblastoma SH-SY5Y cells were pretreated with different concentrations of edaravone prior to the ...