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Duroc; Sus scrofa; chromosomes; genes; genomics; genotyping; haplotypes; industry; quantitative traits; single nucleotide polymorphism; swine
Abstract:
... The number of teats is a morphological trait of high economic relevance for the pig industry. Here, to dissect the genomic architecture of this trait in the Italian Duroc pig population, we present the results of genome-wide association studies in this Italian heavy pig breed. A total of 1,162 pigs, for which the number of teats was recorded, was genotyped with two high-throughput single nucleotid ...
... Staphylococcus aureus is one the most significant causative pathogens of subclinical mastitis in lactating Beetal goats. This study was designed to determine the prevalence of subclinical mastitis caused by Staphylococcus aureus, their susceptibility to different antibiotics, and detection of blaZ gene prevalence in β-lactams resistant Staphylococcus aureus isolates via polymerase chain reaction. ...
... The process of reproductive in domestic livestock is one of the most important challenges of animal husbandry. Fertility is an important trait that contributes to herd profitability, and it can be improved by genomic information. One of the best ways to examine the association between single nucleotide polymorphisms (SNPs) and phenotypic performance is genome-wide association study (GWAS). This st ...
Sus scrofa; boar taint; data collection; genes; genetic variance; genome-wide association study; genotyping; phenotype; pork; quantitative traits; sires; skatole; swine; taste
Abstract:
... The weighted single-step genome-wide association study (WssGWAS) and post-GWAS analysis may be a useful tool to identify quantitative trait loci (QTL) and candidate genes linked to economically important phenotypes, such as boar taint in pigs. The boar taint is an unpleasant taste and smell observable at uncastrated pork cooking. Therefore, we aimed to identify QTL regions and pinpoint candidate g ...
... The benefits of polled beef animals in the value chain have become well known and provides an impetus to beef cattle breeders to select for the POLLED gene. Animal welfare is a major concern and polled animals do not need to be subjected to painful dehorning; additional advantages include lower injury risks during transport and improved safety during handling of the animals. The polled condition h ...
... Heat stress negatively affects the performance, health, and welfare of dairy cattle. Selection for increasing milk yields is lowering the minimum temperature-humidity index at which heat stress starts to depress milk production, and rising global temperatures exacerbates the problem. The average dairy cow in the USA experiences 96 heat stress days during the year if not cooled. Experience and rese ...
... In this study, we compared effects of inulin-rich plant based dietary supplements on the hindgut microbial communities of entire male pigs using 16S rRNA gene metabarcoding. The study was conducted using dried Jerusalem artichokes and dried chicory roots that were supplied to the basal diet one week before slaughter. Both of the experimental diets were formulated to contain the same amount of inul ...
... The agouti signaling protein (ASIP) gene has a crucial role in pigmentation by encoding a protein that binds the melanocortin 1 receptor and stimulates the synthesis of pheomelanin rather than eumelanin. Several studies have suggested that an increased copy number of the ASIP gene might explain the white pigmentation of certain goat breeds, as previously demonstrated in sheep. In the current work, ...
autosomes; cold; fecundity; gene frequency; genes; genetic distance; genetic variation; genome-wide association study; genomics; genotyping; heterozygosity; meat quality; sheep; standard deviation; India
Abstract:
... Knowledge about genetic diversity and selection signatures are very essential for the management and sustainable utilization of sheep genetic resources in India. In this study, we performed a comprehensive genome-wide analysis of genetic diversity and selection signatures using SNP data. A total of 79 animals from three Indian sheep breeds: Changthangi (n = 29), Deccani (n = 24), and Garole (n = 2 ...
... Coat colour and various patterns are the hallmarked qualitative traits studied in cattle as well as other livestock; however, variation in this trait is resultant of interactions and epistasis of a set of genes rather than being a product of a single gene. In this study, GWAS has been conducted from 50K SNP genotype data, with a stratified approach on Vrindavani cattle (n=48). The study was conduc ...
... The molecular and genetic effects of heat stress are not as well understood as physiological effects. Heat Stress response should be considered one component of gene network coordinated across various cells, tissues and systems. Its action seeks to minimize the effects of the environment on cellular functions. The detection of selection signatures can identify genes and mutations associated with p ...
... Candidate gallinacin genes (GAL) were assessed in Fayoumi (F), Rhode Island Red (R) and their crosses (½R½F and ½F½R) using PCR-RFLP technique to detect the associations between GAL 2, GAL 3, GAL 4 and GAL 5 genes and caecal S. typhimurium bacterial count (CSTBC) and IgA, IgY and IgM antibody titers. The solutions of genotypes of GAL genes were calculated by the method of Generalized Least Squares ...
Quarter Horse; effective population size; genes; genetic variation; pedigree; probability; Brazil
Abstract:
... The aims of this study were to evaluate the genetic diversity of the racing line Quarter Horse breed in Brazil and to provide data on the most influential ancestors by pedigree analysis. All horses that had participated in sprint races in Brazil between 1978 and 2016 were evaluated. There were 5,861 athletes horses (2,474 males and 3,387 females) born between 1971 and 2014. These animals were refe ...
Large White; average daily gain; backfat; exosomes; genes; genotyping; glycogen; ham; haplotypes; meat quality; phosphorylase; weight loss
Abstract:
... Italian heavy pig selection programs are based on production (average daily gain, ADG; feed gain ratio, FGR), carcass (weight of lean cuts, LC; ham weight, HW; backfat thickness, BFT) and meat quality traits of the green hams (ham weight loss at first salting, HWLFS; and visible intermuscular fat, VIF). In this study, we evaluated whether a selective genotyping approach previously designed for BFT ...
... The pathogenicity of tibial dyschondroplasia (TD) is unknown; therefore, it has not been completely evacuated. In this study, we planned to find the possible therapeutic role of Celecoxib supplementation in thiram-induced TD chickens.Three hundred sixty (n = 360) broiler chickens were divided into 3 groups as control (C), thiram (T) and Celecoxib supplementary group (ST) for day 1 (8 day old), 2 ( ...
... F4- and F18-positive enterotoxigenic Escherichia coli (ETEC) are well-known pathogens able to cause a severe swine disease with a worldwide economically importance in pig production. Vaccination of piglets with an oral live bivalent F4/F18 Escherichia coli vaccine has shown some promise and efficacy results in preventing ETEC post weaning diarrhoea (PWD); however, currently, there is a lack of kno ...
... Since their domestication, sheep breeds have been a subject of artificial selection directed towards production of wool, meat and milk as well as natural selection associated with regional climates and nutritional conditions. These selection pressures created a large diversity of sheep breeds and the opportunity to study their genetic differentiation. Despite the existence of several studies on ge ...
Elvis Ticiani; Victor Hugo Vieira Rodrigues; Bruna Rodrigues Willhelm; Eduardo Ribeiro; Renato Pereira da Costa Gerger; Carlos Ambrosio; Calvin Ferrell; Roberto Daniel Sainz; Maria Angélica Miglino; José Luiz Rodrigues; Marcelo Bertolini
... The concept of metabolic zonation in the liver proposes that opposing or complementary metabolic pathways are carried out within distinct regions of the liver lobule to maintain optimal metabolic homeostasis. As bovine placentomes differ in mass and shapes within the reproductive tract, which is even more pronounced in cloned-derived concepti, the aims of this study were to investigate the occurre ...
deafness; genes; genetic heterogeneity; genome-wide association study; genomics; head; horses; phenotype; Brazil
Abstract:
... White markings are very common in several horse breeds. These patterns are used for breed characterization, for the identification of animals (records) and might be associated with anomalies such as skin problems and deafness. The aim of the study was to perform genome-wide association analysis to identify genomic regions associated with the presence of white markings on the head and legs of Quart ...
... The profitability of dairy activity is influenced by the genetic selection of economically important traits. In this context, the correct estimation of genetic parameters and the knowledge regarding candidate genes involved in the expression of genetically associated traits may help develop appropriate breeding strategies for the Guzerá breed. In this study, genetic parameters and candidate genes ...
... Genome wide association analyses were conducted for palatability traits in the presence or absence of electrical stimulation. Palatability traits were measured on steaks from Nellore-Angus steers (n = 350). No palatability traits were correlated (r < 0.18) with steer temperament. Nine SNP on BTA 29 from 35.7 Mb to 48.2 Mb were associated with muscle fiber or overall tenderness, and/or connective t ...
... This study aimed to identify genomic regions influencing growth traits in Nellore cattle and evaluate the predictive ability of each trait based on results obtained from single-step genome-wide association analyzes (ssGWAS) considering different single nucleotide polymorphims (SNP) densities of markers. The National Association of Breeders and Researchers provided the dataset, from eighteen Nellor ...
... The ECA23:22999655C>A DMRT3 variant has been described as a causative region for the four-beat gait in horses, however it remains uncertain for the two distinct gait types observed in the Brazilian Mangalarga Marchador (MM) breed. This study aimed to perform a single-step GWAS, prospecting the genetic architecture of the marcha batida (MB) and marcha picada (MP) in MM horses. Phenotypic records fr ...
biotechnology; effective population size; embryo transfer; foals; genes; genetic variation; herds; inbreeding; mares; pedigree; stallions; Argentina
Abstract:
... The Argentine Polo Horse (AP), an autochthonous breed officially created in Argentina in the early 1980s, is globally recognized as the best equid for playing polo. Their breeding is characterized by the use of cutting-edge assisted reproductive techniques such as large-scale embryo transfer (ET) programs and cloning. The aim of this study was to determine the impact of the use of those reproducti ...
Ricardo Zamorano-Algandar; Miguel A. Sánchez-Castro; Ana I. Hernández-Cordero; R. Mark Enns; Scott E. Speidel; Milton G. Thomas; Juan F. Medrano; Gonzalo Rincón; José C. Leyva-Corona; Guillermo Luna-Nevárez; Javier R. Reyna-Granados; Pablo Luna-Nevárez
... Reproductive management in lactating Holstein cattle is a challenge for dairy producers in Northwestern Mexico where a semi-desert, yet humid, environment is predominant. Under such conditions, a superior cow's ability to get pregnant early during postpartum is desirable to reduce the number of days open and improve fertility parameters. The objective of this study was to predict days open (DO) an ...
... The main objective of this study was to investigate the effects of increasing dietary supplementation of crushed sunflower seeds (CSS) in dairy cow diet on mammary expression of genes involved in de novo fatty acid (FA) synthesis, FA desaturation, FA transport/uptake, cholesterol homeostasis, and regulation of transcription. Twenty-four cows were allocated to one of four diets supplemented with CS ...
Pamela I. Otto; Simone E.F. Guimarães; Lucas L. Verardo; Ana Luísa S. Azevedo; Claudia A. Sevillano; Márcia Cristina A. Prata; John Furlong; Célio de Freitas; Rui S. Verneque; Marta Fonseca Martins; João Cláudio C. Panetto; Wanessa A. Carvalho; Arielly O. Garcia; Raquel M. de Paiva Daibert; Marcos Vinícius G.B. da Silva; Marco A. Machado
... Gastrointestinal nematodes (GIN) parasitism is a very important problem on livestock production, especially in cattle, where the infections are usually subclinical making difficult the diagnosis and aggravating the losses caused by these parasites. This study aimed to identify genomic regions associated with nematode fecal egg count (FEC) in a Gir x Holstein F2 experimental population and to ident ...
... Histone deacetylase inhibitors (HDACi) can change the histone acetylation and significantly enhance the developmental competence of the pre-implantation SCNT embryo. To find a suitable histone deacetylase inhibitor to improve the success rate and potentially developmental ability of handmade cloning (HMC) embryos of porcine, we preferred the histone deacetylase inhibitors VPA to study the effect o ...
... Hernia is a condition in which internal organs, most commonly the intestines, protrude through an opening in the layers of muscle and connective tissue. There are two major types of hernia—umbilical and inguinal. This pathology is a serious problem in pig production, leading to economic loss through the cost of surgical intervention, increased mortality rate, and reduced carcass value. The frequen ...
... The objectives of this study were to estimate genetic parameters and identify candidate genes for milk production in Egyptian buffalo using single-step method. Daily milk yield of 174,619 records from 698 buffalo cows were used. Animals with high and low deviated performance were selected for genotyping with Axiom® Buffalo Genotyping array 90 K. Variance components were estimated using AIREMLF90 f ...
beef cattle; cattle breeding; cattle breeds; chest; genes; genetic markers; growth traits; heterozygosity; linear models; loci; marker-assisted selection; phenotype; signal transduction; single nucleotide polymorphism
Abstract:
... Activin A receptor type 1 (ACVR1) annotated for its involvement in some key signaling pathways is one promising candidate for economic traits. The aim of this study was to analyze its phenotypic effects on cattle growth traits. Four variations including two intronic Indels and two exonic SNPs were detected in 840 cattle from five Chinese cattle breeds by DNA-pool sequencing. Variations g.33008_330 ...
... The objective of this study was to validate the effect of the SNPs rs210072660 and rs109221039 of the calpastatin (CAST) gene on meat toughness in Longissimus thoracis muscle aged for 1 d (±0; short-term ageing), 8 d (±1; medium-term ageing) and 15 d (±2; long-term ageing). The samples were obtained in experiments with different management strategies in Parda de Montaña (grazing and concentrate-fe ...
... The aim of the present study was to identify ovine genomic regions and candidate genes impacting on milk traits i.e. milk yield, fat content, protein content and lactose content in the Frizarta dairy sheep. A total number of 481 ewes genotyped with the OvineSNP50 BeadChip were used. Haplotype regression analysis along with multi-locus mixed model analysis was employed to detect genomic markers ass ...
Rhode Island Red; genes; genotyping; heterosis; homozygosity; maternal effect
Abstract:
... A simple crossbreeding experiment between Fayoumi (F) and Rhode Island Red (R) and their F₁ of ½R½F and ½F½R crosses was conducted. A total number of 480 chicks produced from four genetic groups was used to estimate direct additive genetic effects (Gᴵ), maternal effects (Gᴹ) and direct heterosis (Hᴵ) for growth traits by using generalized least squares procedure. The studied traits were body weigh ...
... The present study determined the optimal dose of enzymatically treated Artemisia annua L. (EA) and investigated the effect of dietary EA supplementation on the intestinal antioxidant activity of weaned piglets. Firstly, a total of 300 piglets with an average body weight of 5.62 ± 0.36 kg (21 days of age) were randomly allocated to 5 dietary treatments, including CON, EA1, EA2, EA3, and EA4 groups ...
... The diets of calves predominantly comprise milk and the start of solid feed intake triggers a critical process in terms of the activity of the rumen microbiota and ruminal fermentation. However, little is known about alterations of the rumen bacterial diversity in dairy bull calves induced by milk replacers and other starters, such as solid pellets or hay. Thus, we analyzed the effects of partiall ...
... In this study we aimed to detect selection signatures for ten cattle breeds (1,659 animals) representing three major production types (beef, milk, and dual-purpose). By using Illumina BovineSNP50 genotyping assay and FST statistics (standardized and smoothed across genome in 10-SNP sliding window), we have detected selection signal characteristics for separate breeds as well as for breed groups ac ...
... Effects of cashew nut shell liquid (CNSL) feeding on rumen fermentation and microbial profiles were investigated using Thai native cattle (n = 4) and swamp buffaloes (n = 4). Rumen fistulated animals were assigned to an experiment in one factor design: they were fed a concentrate (1 kg) and rice straw (90% of ad libitum intake) diet supplemented with control pellets followed by CNSL-containing pel ...
... To investigate the effects of Macleaya cordata extract (MCE) on the gut morphology and microbiota, a total of 90 weaned pigs at 35 days of age were allocated to one of two treatments: CON group, fed with basal diet; or MCE group, fed with basal diet supplemented with 50 mg MCE/kg diet. After continuous administration for 28 days, six pigs per group were selected and euthanized to collect the tissu ...
... Freemartinism is a disorder of sex development (DSD) caused by the formation of placental anastomoses between fetuses of different sex. It leads to development of an abnormal reproductive tract in the female fetus, including the presence of testes or ovotestes. In pig production, such conditions can affect both reproductive performance and meat quality, through undesired boar taint. A common appro ...
Duroc; Large White; Pietrain; body weight; carcass weight; carcass yield; cooking quality; crossbreds; finishing; genes; growth performance; intramuscular fat; landraces; muscles; pH; pork; pork quality; raw meat; swine; swine feeding; swine production; trees
Abstract:
... Organic pig production may be conducted with different genetic types and the carcass outcome can differ in fatness content, however, the contribution of each effect to meat quality characteristics is not well established. The objective of this study was to evaluate two genetic types (Duroc x (Gascon x Duroc), Duroc-sired vs. Pietrain x (Landrace x Large White), Pietrain-sired) slaughtered at a dif ...
... Eukaryotic translation initiation factor 5A2 (EIF5A2) is an essential protein closely related to cellular polyamine homeostasis. It is the only cellular protein that contains the unusual amino acid hypusine [Nɛ-(4-amino-2-hydroxybutyl) lysine] which is necessary for the biochemical activity of EIF5A2 and cellular proliferation. In this study, we aim to characterize chicken EIF5A2 and explore its p ...
... The aim of this study was to estimate genetic parameters and to identify genomic regions associated with the calving ease (CE) in precocious Nellore heifers. A total of 1,277 CE phenotypes were collected and scored into two categories: i- non assisted calving, categorized as success (1) and ii- assisted calving where heifers required any form of assistance or intervention to give birth, categorize ...
chromosomes; color; computer software; ears; farms; genes; genetic factors; genetic markers; genome-wide association study; genotyping; phenotype; production technology; rearing; single nucleotide polymorphism; swine; swine breeds; wattles; Italy
Abstract:
... Casertana is an autochthonous pig breed reared in the Central-South of Italy, mainly in extensive or semi-extensive production systems. A small number of animals are registered to the breed herd-book. The population of this breed is not completely fixed for several exterior traits, including ear size (small vs large), ear bearing (forward vs floppy), presence or absence of wattles and coat colour ...
... Reducing the prevalence of hypoxia-induced pulmonary hypertension (PH) remains a challenge to high-altitude beef production systems. Previous research and selection strategies have focused on the impact of bulls with PH in gain-test; however, little information is available on heifers that are typically developed in grazing systems. We hypothesized that indicator traits for PH in heifers are genom ...
... Forty-four pure Iberian pigs were reared under four different rearing systems: i. Free range conditions and fed on acorns and pasture (AGFR), ii. Free range conditions with grass availability and fed on concentrate (CGFR), iii. Intensive system and fed on concentrate supplemented with 100 ppm of α-tocopheryl acetate (α-Tac) (CI) and iv. Intensive system and fed on concentrate supplemented with 200 ...
Ana Paula Del Vesco; Angélica de Souza Khatlab; Thaís Pacheco Santana; Paulo Cesar Pozza; Maria Amélia Menck Soares; Claudson Oliveira Brito; Leandro Teixeira Barbosa; Eliane Gasparino
... The objective of this study was to evaluate the effect of DL-methionine supplementation on the expression of genes related to immune function and intestinal integrity in the jejunum and ileum of 21- or 42-day-old broilers subjected to 38 °C for 24 h. Broilers of 1–21 and 22–42 days of age were divided into two treatments related to methionine supplementation: without DL-methionine supplementation ...
... The endocrine and metabolic changes in early lactating dairy cows can induce inflammation through reactive oxygen species (ROS) impairing liver function. Nuclear erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates the expression of genes encoding antioxidative proteins which diminish inflammatory damage, neutralize ROS and suppress pro-inflammatory signaling, thereby prot ...
Caio Victor Damasceno Carvalho; Isis da Costa Hermisdorff; Isadora Saraiva Souza; Gleb Strauss Borges Junqueira; Ana Fabricia Braga Magalhães; Larissa Fernanda Simielli Fonseca; Lucia Galvão de Albuquerque; Humberto Tonhati; Roberto Carvalheiro; Gregório Miguel Ferreira de Camargo; Raphael Bermal Costa
... Sex chromosomes are generally excluded from genomic analyses, although X chromosome is the second largest chromosome and harbors many genes. The objective of this study was to evaluate the effect of X chromosome by identifying its regions associated with reproductive traits in Nelore cows through a genome-wide association and by estimating its linkage disequilibrium. Phenotypic data of 76,845 and ...
... The objective of this study was to evaluate the effects of forskolin supplementation of the culture medium on the development, lipid content, and transcript levels genes of in vitro-produced bovine embryos. Ovaries (n = 420) from Nelore cows were obtained from the slaughterhouse. On day 5 (D5) of in vitro culture, the embryos in the experimental group were treated with 10 µM of forskolin, and the ...