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- Goulart, Camila Oliveira; Pereira Lopes, Fátima Rosalina; Monte, Zulmira Oliveira; Dantas, Severino Valentim; Souto, Allana; Oliveira, Júlia Teixeira; Almeida, Fernanda Martins; Tonda-Turo, Chiara; Pereira, Cristina Cardoso; Borges, Cristiano Piacsek; Martinez, Ana Maria Blanco
- Methods 2016 v.99 pp. 28-36
- allergenicity; autografting; biocompatibility; biocompatible materials; biodegradability; blood vessels; cell viability; electron microscopy; extrusion; mice; models; morphometry; nerve fibers; nerve tissue; polyesters; polylactic acid; porous media; quantitative analysis
- ... Polymeric biomaterials are often used for stimulating nerve regeneration. Among different conduits, poly(lactide acid) – PLA polymer is considered to be a good substrate due to its biocompatibility and resorbable characteristics. This polymer is an aliphatic polyester which has been mostly used in biomedical application. It is an organic compound with low allergenic potential, low toxicity, high b ...
- Richardson, Stephen M.; Kalamegam, Gauthaman; Pushparaj, Peter N.; Matta, Csaba; Memic, Adnan; Khademhosseini, Ali; Mobasheri, Reza; Poletti, Fabian L.; Hoyland, Judith A.; Mobasheri, Ali
- Methods 2016 v.99 pp. 69-80
- adipose tissue; biocompatible materials; biomimetics; bone marrow; chondrocytes; chondrogenesis; intervertebral disks; medicine; morbidity; musculoskeletal diseases; signal transduction; stem cells; therapeutics; umbilical cord
- ... Musculoskeletal disorders represent a major cause of disability and morbidity globally and result in enormous costs for health and social care systems. Development of cell-based therapies is rapidly proliferating in a number of disease areas, including musculoskeletal disorders. Novel biological therapies that can effectively treat joint and spine degeneration are high priorities in regenerative m ...