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- Chen, Xiaonan; Li, Pengyu; Shen, Yuanna; Zou, Yiqing; Yuan, Gang; Hu, Haiyan
- Microbial pathogenesis 2019 v.131 pp. 112-119
- Helicobacter pylori; adjuvants; amoxicillin; bacteria; bacterial adhesion; biofilm; biomass; clarithromycin; combination drug therapy; plankton; polymers; proton pump inhibitors; relapse; rhamnolipids
- ... Antibiotics resistance of H. pylori has been increasing constantly accompanied with decreasing clearance rate clinically, which is demonstrated to be closely related to biofilms with higher resistance than planktonic bacteria for the dense extracellular polymeric substances. Rhamnolipid (RHL) is proved to not only damage the structure of biofilm, but also potentially inhibit bacterial adhesion. To ...