PubAg

Main content area

Search

4  Search Results

1 - 4 of 4
Number of results to display per page

Search Results

1. Anti-staphylococcal activity of Syagrus coronata essential oil: Biofilm eradication and in vivo action on Galleria mellonela infection model

Author:
Souza dos Santos, Bruno; Bezerra Filho, Clóvis Macedo; Alves do Nascimento Junior, José Adelson; Brust, Flávia Roberta; Bezerra-Silva, Patrícia Cristina; Lino da Rocha, Suyana Karoline; Krogfelt, Karen Angeliki; Maria do Amaral Ferraz Navarro, Daniela; Tereza dos Santos Correia, Maria; Napoleão, Thiago Henrique; Nascimento da Silva, Luís Claudio; Macedo, Alexandre José; Vanusa da Silva, Márcia; Guedes Paiva, Patrícia Maria
Source:
Microbial pathogenesis 2019 v.131 pp. 150-157
ISSN:
0882-4010
Subject:
Galleria mellonella; Staphylococcus aureus; Syagrus coronata; antibacterial properties; antibiotics; bacteria; biofilm; biomass; cell viability; decanoic acid; dodecanoic acid; drugs; electron microscopy; essential oils; hemolymph; larvae; melanization; microbial load; minimum inhibitory concentration; models; multiple drug resistance; octanoic acid; phenotype; roughness; seeds; sesquiterpenoids
Abstract:
... In this study, essential oil extracted from Syagrus coronata seeds (SCEO) was evaluated for antibacterial and antibiofilm activities against Staphylococcus aureus; in addition, Galleria mellonella model was used as an in vivo infection model. SCEO was mainly composed by fatty acids (89.79%) and sesquiterpenes (8.5%). The major components were octanoic acid, dodecanoic acid, decanoic acid and γ-eud ...
DOI:
10.1016/j.micpath.2019.04.009

2. Characterization of serine acetyltransferase (CysE) from methicillin-resistant Staphylococcus aureus and inhibitory effect of two natural products on CysE

Author:
Chen, Changming; Yan, Qiulong; Tao, Mengxing; Shi, Huaying; Han, Xiuyan; Jia, Liqiu; Huang, Yukun; Zhao, Lizhe; Wang, Chao; Ma, Xiaochi; Ma, Yufang
Source:
Microbial pathogenesis 2019 v.131 pp. 218-226
ISSN:
0882-4010
Subject:
antibiotic resistance; bacteria; biofilm; biosynthesis; colorimetry; computer simulation; cysteine; drugs; enzyme activity; inhibitory concentration 50; methicillin; methicillin-resistant Staphylococcus aureus; models; pathogens; screening; serine O-acetyltransferase; site-directed mutagenesis; viability
Abstract:
... Methicillin-resistant Staphylococcus aureus (MRSA) is a major hospital-acquired infective pathogen that has developed resistance to many antibiotics. It is imperious to develop novel anti-MRSA drugs to control the emergence of drug resistance. The biosynthesis of cysteine in bacteria is catalyzed by CysE and CysK. CysE was predicted to be important for bacterial viability, it could be a potential ...
DOI:
10.1016/j.micpath.2019.04.002

3. Influences of stress hormones on microbial infections

Author:
Sarkodie, Emmanuel Konadu; Zhou, Shuxin; Baidoo, Sarah Ama; Chu, Weihua
Source:
Microbial pathogenesis 2019 v.131 pp. 270-276
ISSN:
0882-4010
Subject:
aquaculture industry; bacteria; bacterial growth; bacterial infections; biofilm; brain; digestive system; dopamine; epinephrine; gene expression; genes; hosts; immune system; intestinal microorganisms; iron; mechanism of action; microbiome; norepinephrine; siderophores; virulence
Abstract:
... Stress hormones have been recently suggested to influence the pathogenicity of bacteria significantly. Stress has been identified as part of the factors causing an outbreak of infections in the aquaculture industry. The most studied neuroendocrine hormonal family from a microbial endocrinology perspective is the catecholamine comprising of norepinephrine, epinephrine, and dopamine. It is of import ...
DOI:
10.1016/j.micpath.2019.04.013

4. Rhamnolipid-involved antibiotics combinations improve the eradication of Helicobacter pylori biofilm in vitro: A comparison with conventional triple therapy

Author:
Chen, Xiaonan; Li, Pengyu; Shen, Yuanna; Zou, Yiqing; Yuan, Gang; Hu, Haiyan
Source:
Microbial pathogenesis 2019 v.131 pp. 112-119
ISSN:
0882-4010
Subject:
Helicobacter pylori; adjuvants; amoxicillin; bacteria; bacterial adhesion; biofilm; biomass; clarithromycin; combination drug therapy; plankton; polymers; proton pump inhibitors; relapse; rhamnolipids
Abstract:
... Antibiotics resistance of H. pylori has been increasing constantly accompanied with decreasing clearance rate clinically, which is demonstrated to be closely related to biofilms with higher resistance than planktonic bacteria for the dense extracellular polymeric substances. Rhamnolipid (RHL) is proved to not only damage the structure of biofilm, but also potentially inhibit bacterial adhesion. To ...
DOI:
10.1016/j.micpath.2019.04.001