Jump to Main Content
PubAg
Main content area
Search
« Previous |
1 - 20 of 29
|
Next »
Search Results
- Author:
- Matsunaga, Shinsuke; Nishiumi, Shin; Tagawa, Ryoma; Yoshida, Masaru
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Helicobacter pylori; amino acid metabolism; aspartate-ammonia ligase; bacteria; epithelial cells; gastric mucosa; glycolysis; humans; isocitrate dehydrogenase; metabolites; neoplasm cells; pathogens; signal transduction; tricarboxylic acid cycle; virulence
- Abstract:
- ... Helicobacter pylori (H. pylori), which is a spiral-shaped Gram-negative microaerobic bacterium, is a causative pathogen. The entry of H. pylori into gastric epithelial cells involves various host signal transduction events, and its virulence factors can also cause a variety of biological responses. In this study, AGS human gastric carcinoma cells were infected with CagA-positive H. pylori strain A ...
- DOI:
- 10.1016/j.micpath.2018.08.033
-
http://dx.doi.org/10.1016/j.micpath.2018.08.033
- Author:
- Bashiru, Garba; Bahaman, Abdul Rani; Zakaria, Zunita; Bejo, Siti Khairani; Mutalib, Abdul Rahim; Faruku, Bande; Suleiman, Nasiru
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- DNA; Leptospira; animals; cross immunity; epitopes; genes; hosts; immunization; leptospirosis; neutralizing antibodies; recombinant vaccines; serotypes; subtropics
- Abstract:
- ... Leptospirosis is a serious epidemic disease caused by pathogenic Leptospira species. The disease is endemic in most tropical and sub-tropical regions of the world. Currently, there is no effective polyvalent vaccine for prevention against most of the circulating serovars. Moreover, development of an efficient leptospiral vaccine capable of stimulating cross-protective immune responses against a wi ...
- DOI:
- 10.1016/j.micpath.2018.08.028
-
http://dx.doi.org/10.1016/j.micpath.2018.08.028
- Author:
- Ferreira, Gustavo Ramos Salles; Brito, Jéssica de Santana; Procópio, Thamara Figueiredo; Santos, Nataly Diniz de Lima; de Lima, Bárbara José Rocha Cardoso; Coelho, Luana Cassandra Breitenbach Barroso; Navarro, Daniela Maria do Amaral Ferraz; Paiva, Patrícia Maria Guedes; Soares, Tatiana; de Moura, Maiara Celine; Napoleão, Thiago Henrique
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Alpinia purpurata; Candida albicans; Candida parapsilosis; Pseudomonas aeruginosa; Staphylococcus aureus; abnormal development; animal pathogens; antibacterial properties; antibiotics; antifungal properties; biofilm; humans; lectins; minimum inhibitory concentration; multiple drug resistance; propidium; staining; synergism; viability
- Abstract:
- ... The Alpinia purpurata inflorescence contains a lectin (ApuL), which has immunomodulatory activities on human cells. In the present work, it was evaluated the antibacterial and antifungal effects of ApuL against human pathogens. ApuL showed bacteriostatic activity against non-resistant (UFPEDA-02) and an oxacillin-resistant isolate (UFPEDA-672) of Staphylococcus aureus with minimal inhibitory conce ...
- DOI:
- 10.1016/j.micpath.2018.08.027
-
http://dx.doi.org/10.1016/j.micpath.2018.08.027
- Author:
- Sun, Xiang; Lin, Zhi-wei; Hu, Xiao-xiong; Yao, Wei-ming; Bai, Bing; Wang, Hong-yan; Li, Duo-yun; Chen, Zhong; Cheng, Hang; Pan, Wei-guang; Deng, Ming-gui; Xu, Guang-jian; Tu, Hao-peng; Chen, Jun-wen; Deng, Qi-wen; Yu, Zhi-jian; Zheng, Jin-xin
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- antibiotic resistance; biofilm; ciprofloxacin; clindamycin; erythromycin; essential genes; gentamicin; gentian violet; methicillin; methicillin-resistant Staphylococcus aureus; multilocus sequence typing; polymerase chain reaction; resistance genes; staining; China
- Abstract:
- ... In this study, we aimed to investigate biofilm formation characteristics in clinical Staphylococcus aureus (S. aureus) isolates with erythromycin (ERY) resistance from China and further analyze their correlations with antimicrobial susceptibility and molecular characteristics.ology A total of 276 clinical isolates of ERY-resistant S. aureus, including 142 methicillin-resistant S. aureus (MRSA) str ...
- DOI:
- 10.1016/j.micpath.2018.08.021
-
https://dx.doi.org/10.1016/j.micpath.2018.08.021
- Author:
- de Queiroz Dias, Diógenes; Sales, Débora Lima; Andrade, Jacqueline Cosmo; Pereira da Silva, Ana Raquel; Tintino, Saulo Relison; Datiane de Morais Oliveira-Tintino, Cícera; de Araújo Delmondes, Gyllyandeson; Gadelha Rocha, Marcos Fábio; Martins da Costa, José Galberto; Romeu da Nóbrega Alves, Rômulo; Ferreira, Felipe Silva; Melo Coutinho, Henrique Douglas; de Oliveira Almeida, Waltécio
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Meleagris gallopavo; amikacin; amoxicillin; antibacterial properties; bacteria; chemical composition; chickens; fatty acid methyl esters; hexane; linoleic acid; minimum inhibitory concentration; norfloxacin; oils; oleic acid; oxytetracycline; saturated fatty acids; solvents; synergism; Brazil
- Abstract:
- ... In the Northeast of Brazil, ethnoveterinary studies have shown that the body fat from Gallus gallus domesticus and Meleagris gallopavo are used for diseases that affect domestic animals. The objective of this study was to identify the chemical composition and to evaluate the antibacterial activity of the Gallus gallus domesticus (OFGG) and Meleagris gallopavo (OFMG) fixed oils in isolation and in ...
- DOI:
- 10.1016/j.micpath.2018.08.029
-
http://dx.doi.org/10.1016/j.micpath.2018.08.029
- Author:
- Júnior da Silva, Jeferson; da Silva, Thaísla Andrielli; de Almeida, Hudson; Rodrigues Netto, Manoel Francisco; Cerdeira, Claudio Daniel; Höfling, José Francisco; Gomes Boriollo, Marcelo Fabiano
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Candida; DNA; amphotericin B; biotypes; children; cultural behavior; culture media; electrophoresis; extracellular enzymes; females; fluconazole; infants; infectious diseases; males; mouth; nucleotide sequences; nystatin; patients; polyenes; polymerase chain reaction; risk factors; surgery; virulence
- Abstract:
- ... Patients with orofacial clefts present various risk factors for oral infectious diseases, resulting from anatomical and physiological changes and those resulting from rehabilitating therapeutic interventions. The incidence of Candida species in groups of babies and children with orofacial clefts, during pre- and post-operative periods and until return to first consultation, and the profiles for an ...
- DOI:
- 10.1016/j.micpath.2018.08.042
-
http://dx.doi.org/10.1016/j.micpath.2018.08.042
- Author:
- Taghizadeh, Seyedeh Faezeh; Davarynejad, Gholamhossein; Asili, Javad; Riahi-Zanjani, Bamdad; Nemati, Seyed Hossein; Karimi, Gholamreza
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Pistacia khinjuk; Staphylococcus aureus; antioxidant activity; antioxidants; bacteria; bleaching; cell lines; chemical composition; cytotoxicity; essential oils; gas chromatography-mass spectrometry; inhibitory concentration 50; minimum inhibitory concentration; oils; pistachios
- Abstract:
- ... Chemical composition, antibacterial, antioxidant and cytotoxic activities of (Pistacia khinjuk) hull essential oil (EO) were evaluated in this study. The EO was isolated and analyzed by gas chromatography-mass spectrometry. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) were determined using 6 strains of Gram-positive and negative bacteria. DPPH radical ...
- DOI:
- 10.1016/j.micpath.2018.08.039
-
http://dx.doi.org/10.1016/j.micpath.2018.08.039
- Author:
- Hambali, I.U.; Bhutto, K.R.; Jesse, F.F.A.; Lawan, A.; Odhah, M.N.; Wahid, A.H.; Azmi, M.L. Mohd; Zakaria, Z.; Arsalan, M.; Muhammad, N.A.; Jefri, M.N.
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Staphylococcus aureus; adjuvants; algae; aluminum; bacteria; cows; fungi; heart rate; leukocytes; mastitis; potassium sulfate; prototypes; respiratory rate; temperature; udders; vaccination; vaccines; viruses
- Abstract:
- ... Mastitis is an inflammatory condition of the udder that occurs as a result of the release of leucocytes into the udder in a response to bacterial invasion. The major causes of mastitis are an array of gram positive and negative bacteria, however, algae, virus, fungi, mechanical or thermal injury to the gland have also been identified as possible causes. Mastitis vaccines are yet to be developed us ...
- DOI:
- 10.1016/j.micpath.2018.08.017
-
http://dx.doi.org/10.1016/j.micpath.2018.08.017
- Author:
- Liu, Xianbing; Jiang, Mengqi; Ren, Liqin; Zhang, Aihong; Zhao, Mingdong; Zhang, Haixia; Jiang, Yuzhu; Hu, Xuemei
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Toxoplasma gondii; animal models; immunosuppression; inducible nitric oxide synthase; interleukin-12; macrophages; mice; phenotype; placenta; pre-eclampsia; pregnancy outcome; tumor necrosis factor-alpha
- Abstract:
- ... Recent evidence indicates that macrophages at the maternal–fetal interface adapt to a phenotype characterized by alternative activation (M2 polarization) and exhibit immunosuppressive functions that favor the maintenance of pregnancy. The bias of M2 decidual macrophages toward M1 has been clinically linked to pregnancy-related complications, such as preeclampsia, and preterm delivery. The aim of t ...
- DOI:
- 10.1016/j.micpath.2018.08.043
-
http://dx.doi.org/10.1016/j.micpath.2018.08.043
- Author:
- Sundarmoorthy, Niranjana Sri; Mithra, Karthik; Ganesh, Jayasankari Senthil; Makala, Himesh; Lotha, Robert; Bhanuvalli, Shamprasad R.; Ulaganathan, Venkatasubramanian; Thirunaukarasu, Vaidehi; Sivasubramanian, Aravind; Nagarajan, Saisubramanian
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Danio rerio; acetates; adjuvants; animal models; ciprofloxacin; ferulic acid; methicillin-resistant Staphylococcus aureus; molecular models; muscle tissues; prediction; reserpine; transporters
- Abstract:
- ... A series of ferulic acid (FA) derivatives were synthesized and evaluated for its ability to inhibit NorA efflux in methicillin resistant Staphylococcus aureus (MRSA), by in silico docking analysis. Based on prediction from glide scores and ability to reduce EtBr MIC, two of the ten derivatives S3- [4-((E)-2-(diethylcarbamoyl)vinyl)-2-methoxyphenyl acetate] and S6- [(E)-methyl 3-(4-((p-tolylcarbamo ...
- DOI:
- 10.1016/j.micpath.2018.08.022
-
https://dx.doi.org/10.1016/j.micpath.2018.08.022
- Author:
- Gao, Xiang; Bao, Shijun; Xing, Xiaoyong; Fu, Xiaoping; Zhang, Yi; Xue, Huiwen; Wen, Fengqin; Wei, Yanming
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Escherichia coli; Mycoplasma bovis; NAD (coenzyme); adhesins; adhesion; antibodies; bacteria; bacterial adhesion; blood serum; cattle; cattle industry; cell membranes; complement; cytoplasm; dose response; electrophoresis; enzyme activity; enzyme-linked immunosorbent assay; financial economics; fluorescence microscopy; fluorescent antibody technique; fructose-bisphosphate aldolase; genes; genetic vectors; glycolysis; lungs; plasmids; plasminogen; polymerase chain reaction; rabbits
- Abstract:
- ... Mycoplasma bovis is an extremely small cell wall-deficient pathogenic bacterium in the genus Mycoplasma that causes serious economic losses to the cattle industry worldwide. Fructose-1,6-bisphosphate aldolase (FBA), a key enzyme in the glycolytic pathway, is a multifunctional protein in several pathogenic bacterial species, but its role in M. bovis remains unknown. Herein, the FBA gene of the M. b ...
- DOI:
- 10.1016/j.micpath.2018.08.032
-
http://dx.doi.org/10.1016/j.micpath.2018.08.032
- Author:
- Jwa, Min Yong; Ko, Eun Byeol; Kim, Hyun Young; Kim, Sun Kyung; Jeong, Soyoung; Seo, Ho Seong; Yun, Cheol-Heui; Han, Seung Hyun
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Streptococcus pneumoniae; Toll-like receptor 2; cost effectiveness; epithelial cells; epithelium; formalin; heat; human cell lines; humans; immunogenicity; immunostimulants; innate immunity; interleukin-6; interleukin-8; meningitis; messenger RNA; mitogen-activated protein kinase; otitis media; pathogens; pneumonia; polysaccharides; protein content; vaccines
- Abstract:
- ... Streptococcus pneumoniae is a major respiratory pathogen that can cause pneumonia, meningitis, and otitis media. Although capsular polysaccharide-based vaccines are commercially available, there is a need for broad-spectrum, serotype-independent, and cost-effective vaccines. Recently, an intranasal vaccine formulated with gamma-irradiated nonencapsulated S. pneumoniae whole cells has been develope ...
- DOI:
- 10.1016/j.micpath.2018.08.015
-
https://dx.doi.org/10.1016/j.micpath.2018.08.015
- Author:
- Lone, Jameel Barkat; Koh, Wee Yin; Parray, Hilal A.; Paek, Woon K.; Lim, Jeongheui; Rather, Irfan A.; Jan, Arif Tasleem
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- comorbidity; diet; energy; etiology; genetic factors; intestinal microorganisms; lifestyle; obesity; people; therapeutics
- Abstract:
- ... Obesity and obesity-related comorbidities have transformed into a global epidemic. The number of people suffering from obesity has increased dramatically within the past few decades. This rise in obesity cannot alone be explained by genetic factors; however, diet, environment, lifestyle, and presence of other diseases undoubtedly contribute towards obesity etiology. Nevertheless, evidence suggests ...
- DOI:
- 10.1016/j.micpath.2018.08.036
-
http://dx.doi.org/10.1016/j.micpath.2018.08.036
- Author:
- Hirai, Kelly Emi; Silva, Luciana Mota; de Sousa, Jorge Rodrigues; de Souza, Juarez; Dias, Leônidas Braga; Oliveira Carneiro, Francisca Regina; de Souza Aarão, Tinara Leila; Quaresma, Juarez Antonio Simões
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Mycobacterium leprae; antigens; dendritic cells; immune response; leprosy; pathogenesis; patients; skin lesions
- Abstract:
- ... Leprosy is a disease caused by Mycobacterium leprae, which is characterized by two distinct poles, the tuberculoid pole and the lepromatous pole, depending on the immune response to the bacillus. Langerin-positive cells are dendritic cells that appear to play an essential role in the development of the disease. These cells are specialized in the processing and presentation of antigens, exerting an ...
- DOI:
- 10.1016/j.micpath.2018.08.020
-
https://dx.doi.org/10.1016/j.micpath.2018.08.020
- Author:
- Bonsaglia, E.R.; Silva, N.C.C.; Rossi, B.F.; Camargo, C.H.; Dantas, S.T.A.; Langoni, H.; Guimarães, F.F.; Lima, F.S.; Fitzgerald, J.R.; Fernandes, A.; Rall, V.L.M.
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Staphylococcus aureus; bovine mastitis; clindamycin; clones; cows; dairy herds; enterotoxins; erythromycin; farms; genes; milk; molecular epidemiology; multilocus sequence typing; phenotype; polymerase chain reaction; pulsed-field gel electrophoresis; septic shock; streptomycin; swine; Brazil
- Abstract:
- ... Bovine mastitis has been a concern for dairy herd for decades. The adaptation capacity of one of the main species responsible for this disease, Staphylococcus aureus (S. aureus), plays a pivotal role in this issue. The aim of this study was to establish a molecular and phenotypic profile of 285 S. aureus strains isolated from milk of subclinical mastitis cows from 18 different farms in São Paulo S ...
- DOI:
- 10.1016/j.micpath.2018.08.031
-
http://dx.doi.org/10.1016/j.micpath.2018.08.031
- Author:
- Medrano-Díaz, César Luis; Vega-González, Arturo; Ruiz-Baca, Estela; Moreno, Abel; Cuéllar-Cruz, Mayra
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Candida albicans; Candida glabrata; animal models; biofilm; candidiasis; cell walls; fructose-bisphosphate aldolase; humans; immunity; kidneys; liver; medical equipment; mice; oxidative stress; pathogens; patients; phosphoglycerate kinase; pyruvate kinase; reactive oxygen species; recombinant proteins; spleen; structural proteins; vaccines; virulence; yeasts
- Abstract:
- ... In recent years, C. albicans and C. glabrata have been identified as the main cause of candidemia and invasive candidiasis in hospitalized and immunocompromised patients. In order to colonize the human host, these fungi express several virulence factors such as the response to oxidative stress and the formation of biofilms. In the expression of these virulence factors, the cell wall of C. albicans ...
- DOI:
- 10.1016/j.micpath.2018.08.024
-
https://dx.doi.org/10.1016/j.micpath.2018.08.024
- Author:
- Heng, Yin; Mao, Wu; Yong, Ma; Yang, Guo; Su, Qiuju; Wang, Jianwei
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- inflammation; interleukin-1beta; interleukin-6; lipopolysaccharides; malondialdehyde; protein content; superoxide dismutase; tumor necrosis factor-alpha
- Abstract:
- ... This study was to investigate the effects of paeoniflorin (PA) on lipopolysaccharides (LPS)-induced nucleus pulposus cells. Our results demonstrated that PA significantly reduced lipopolysaccharides (LPS) induced inflammatory factors including interleukin-1β (IL-1β), tumor necrosis Factor-α (TNF-α) and interleukin-6 (IL-6) in nucleus pulposus cells. PA also decreased of malondialdehyde (MDA) and i ...
- DOI:
- 10.1016/j.micpath.2018.08.009
-
http://dx.doi.org/10.1016/j.micpath.2018.08.009
- Author:
- Rishi, Praveen; Vij, Shania; Maurya, Indresh Kumar; Kaur, Ujjwal Jit; Bharati, Sanjay; Tewari, Rupinder
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- adjuvants; ampicillin; antibiotic resistance; antimicrobial properties; confocal microscopy; dielectric spectroscopy; ethidium; flow cytometry; mechanism of action; methicillin; methicillin-resistant Staphylococcus aureus; minimum inhibitory concentration; multiple drug resistance; oxacillin; pathogens; peptides; proteins; scanning electron microscopy; screening
- Abstract:
- ... Fast emerging antibiotic resistance in pathogens requires special attention for strengthening the reservoir of antimicrobial compounds. In view of this, several peptides with known antimicrobial activities have been reported to enhance the efficacy of antibiotics against multidrug resistant (MDR) pathogens. In the present study, potential of peptides having distinct mechanism of action, if any, wa ...
- DOI:
- 10.1016/j.micpath.2018.08.023
-
https://dx.doi.org/10.1016/j.micpath.2018.08.023
- Author:
- Duan, Xingyu; Hays, Aislinn; Zhou, Wei; Sileewa, Nawar; Upadhyayula, Satya; Wang, Huizhi; Liang, Shuang
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Porphyromonas gingivalis; animal models; bone resorption; cytokines; inflammation; mice; microbial load; periodontal diseases; pregnancy; pregnant women; quantitative polymerase chain reaction
- Abstract:
- ... Although pregnant women are prone to gingival inflammation, its mechanism remains unclear. Animal models are ideal for investigating immunological mechanisms in the periodontal disease. A murine model for ligature-induced periodontal disease has been modified and utilized to determine the susceptibility to periodontal inflammation and tissue damage in pregnant mice. Expression of different inflamm ...
- DOI:
- 10.1016/j.micpath.2018.08.019
- PubMed:
- 30118804
- PubMed Central:
- PMC6365183
-
http://dx.doi.org/10.1016/j.micpath.2018.08.019
- Author:
- Tabrizi, Niloufar Mirzaee; Amani, Jafar; Ebrahimzadeh, Mohammad; Nazarian, Shahram; Kazemi, Rohoallah; Almasian, Pegah
- Source:
- Microbial pathogenesis 2018
- ISSN:
- 0882-4010
- Subject:
- Gram-negative bacteria; Vibrio cholerae; Western blotting; antigens; blood serum; chitosan; cholera; diarrhea; enzyme-linked immunosorbent assay; ileum; immune response; immunogenicity; immunoglobulin A; immunoglobulin G; mice; nanoparticles; neutralization; polyacrylamide gel electrophoresis; rabbits; vaccines
- Abstract:
- ... Vibrio cholera is a Gram-negative pathogen that causes diarrheal disease. The B subunit of Chlora toxin (CtxB) is one of the most important antigens of Vibrio cholera in which mediates the attachment of the bacteria to target cells. The aim of this study was to prepare chitosan nanoparticles containing CtxB and evaluate the effect of the antigen entrapment on the immunogenicity of this antigen.For ...
- DOI:
- 10.1016/j.micpath.2018.08.037
-
http://dx.doi.org/10.1016/j.micpath.2018.08.037