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- Mohanvel, Sucharitha Kannappan, et al. Show all 7 Authors
- Microbial pathogenesis 2019 v.130 pp. 104-111
- Pseudomonas aeruginosa; active sites; antimicrobial properties; biofilm; computer simulation; dose response; genes; mechanism of action; messenger RNA; moieties; multiple drug resistance; pathogenesis; pathogens; pyocyanin; quorum sensing; urea
- ... Emergence of multi-drug resistant bacterial pathogens is escalating and it is essential to develop novel strategies to combat these super bugs. LasR is a regulator switch that plays a vital role in quorum sensing (QS) and pathogenesis of Pseudomonas aeruginosa. The present study reports two novel Mannich base (1-(phenyl (o-tolylamino) methyl) urea and 3-((1H-Imidazole-1-yl) methylnaphthalene-2-ol ...