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- Asadi, Jalal; Ferguson, Sophie; Raja, Hussain; Hacker, Christian; Marius, Phedra; Ward, Richard; Pliotas, Christos; Naismith, James; Lucocq, John
- Micron 2017 v.99 pp. 40-48
- acetates; drying; endosomes; equipment; exosomes; heavy metals; image analysis; lipids; medicine; methylcellulose; nanoparticles; phosphotungstic acid; sodium; transmission electron microscopy; virion
- ... Synthetic and naturally occurring lipid-rich nanoparticles are of wide ranging importance in biomedicine. They include liposomes, bicelles, nanodiscs, exosomes and virus particles. The quantitative study of these particles requires methods for high-resolution visualization of the whole population. One powerful imaging method is cryo-EM of vitrified samples, but this is technically demanding, requi ...
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