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- Skarra, Danalea V.; Thackray, Varykina G.
- Molecular and Cellular Endocrinology 2015 v.405 pp. 14-24
- apoptosis; cell proliferation; cytoplasm; insulin; insulin-like growth factor I; metabolism; phosphorylation; signal transduction; transcription factors
- ... The FOXO1 transcription factor is important for multiple aspects of reproductive function. We previously reported that FOXO1 functions as a repressor of gonadotropin hormone synthesis, but how FOXO1 is regulated in pituitary gonadotropes is unknown. The growth factors, insulin and insulin-like growth factor I (IGF1), function as key regulators of cell proliferation, metabolism and apoptosis in mul ...
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