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- Wang, A. Hongjun, et al. Show all 20 Authors
- Molecular cell 2018 v.71 no.1 pp. 129-141.e8
- RNA; cell differentiation; chromatin; gene expression; genes; loci; myogenin; transcription (genetics)
- ... The enhancer regions of the myogenic master regulator MyoD give rise to at least two enhancer RNAs. Core enhancer eRNA (CᴱeRNA) regulates transcription of the adjacent MyoD gene, whereas ᴰᴿᴿeRNA affects expression of Myogenin in trans. We found that ᴰᴿᴿeRNA is recruited at the Myogenin locus, where it colocalizes with Myogenin nascent transcripts. ᴰᴿᴿeRNA associates with the cohesin complex, and t ...
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