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- Levo, Michal; Avnit-Sagi, Tali; Lotan-Pompan, Maya; Kalma, Yael; Weinberger, Adina; Yakhini, Zohar; Segal, Eran
- Molecular cell 2017 v.65 no.4 pp. 604-617.e6
- DNA; gene expression; gene expression regulation; nucleosomes; regulatory sequences; transcription factors; yeasts
- ... Precise gene expression patterns are established by transcription factor (TFs) binding to regulatory sequences. While these events occur in the context of chromatin, our understanding of how TF-nucleosome interplay affects gene expression is highly limited. Here, we present an assay for high-resolution measurements of both DNA occupancy and gene expression on large-scale libraries of systematicall ...