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- Trizzino, Marco, et al. Show all 8 Authors
- Molecular cell 2018 v.71 no.1 pp. 103-116.e7
- cell lines; chromatin; epigenetics; genes; humans; nucleotide motifs; transactivators; transcription (genetics)
- ... The control of cell fate is an epigenetic process initiated by transcription factors (TFs) that recognize DNA motifs and recruit activator complexes and transcriptional machineries to chromatin. Lineage specificity is thought to be provided solely by TF-motif pairing, while the recruited activators are passive. Here, we show that INTS13, a subunit of the Integrator complex, operates as monocytic/m ...