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- Jong, Yuh-Jyh, et al. Show all 9 Authors
- Molecular nutrition & food research 2011 v.55 no.2 pp. 318-327
- adenocarcinoma; adhesion; angiogenesis; breast neoplasms; breasts; cell invasion; endothelial cells; humans; licorice; mice; myosin light chains; roots; umbilical veins
- ... Scope: In this study we first report the antimigration, antiinvasive effect of glabridin, a flavonoid obtained from licorice, in MDA-MB-231 human breast adenocarcinoma cells. Methods and results: Glabridin exhibited effective inhibition of cell metastasis by decreasing cancer cell migration and invasion of MDA-MB-231 cells. In addition, glabridin also blocked human umbilical vein endothelial cells ...
- Jong, Yuh-Jyh, et al. Show all 7 Authors
- Molecular nutrition & food research 2010 v.54 no.9 pp. 1307-1317
- apoptosis; ascorbic acid; breast neoplasms; caspase-9; cell cycle; cell growth; ginger; humans; mitogen-activated protein kinase; oxygen; reactive oxygen species
- ... This study is the first to investigate the anticancer effect of 6-dehydrogingerdione (DGE), an active constituent of dietary ginger, in human breast cancer MDA-MB-231 and MCF-7 cells. DGE exhibited effective cell growth inhibition by inducing cancer cells to undergo G2/M phase arrest and apoptosis. Blockade of cell cycle was associated with increased levels of p21, and reduced amounts of cyclin B1 ...