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- Batista, Daniela; Falé, Pedro L.; Serralheiro, Maria L.; Araújo, Maria E.; Madeira, Paulo J. A.; Borges, Carlos; Torgal, Isabel; Goulart, Margarida; Justino, Jorge; Martins, Alice; Rauter, Amélia P.
- Nat. Prod. Bioprospect. 2015 v.5 no.6 pp. 277-285
- Genista; acarbose; alpha-glucosidase; anti-inflammatory activity; antioxidant activity; ascorbic acid; blood glucose; butanol; carbohydrate metabolism; chemical composition; enzyme activity; enzyme inhibition; flavonoids; gastrointestinal system; glucose-6-phosphatase; glycemic effect; glycosides; hepatoma; in vitro digestion; inflammation; irradiation; liver; noninsulin-dependent diabetes mellitus; oxidative stress; pancreatic juice; rats; ultraviolet radiation; viability
- ... The inhibition of α-glucosidase and glucose-6-phosphatase, two enzymes involved in the carbohydrate metabolism, is an important target to control glycaemia on individuals with type 2 diabetes. In this work we report for the first time the inhibition of both enzymes by the antihyperglycemic n-butanol extract from Genista tenera (Fabaceae). This extract decreased α-glucosidase and glucose-6-phosphat ...
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