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- Author:
- Diao, Shengbao; Jin, Mei; Sun, Jinfeng; Zhou, Yi; Ye, Chao; Jin, Yong; Zhou, Wei; Li, Gao
- Source:
- Natural product research 2019 v.33 no.5 pp. 701-707
- ISSN:
- 1478-6427
- Subject:
- Juglans mandshurica; anti-inflammatory activity; glycosides; heptane; interleukin-6; nitric oxide; nuclear magnetic resonance spectroscopy; roots; tumor necrosis factor-alpha
- Abstract:
- ... A new diarylheptanoid, (2S,3S,5S)-2,3,5-trihydroxy-1,7-bis(4-hydroxy- 3-methoxyphenyl)heptane (1), and a new diarylheptanoid glycoside, (2S,3S,5S)-2,3-dihydroxy-5-O-β-d-xylopyranosyl-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)heptane (2), together with three known compounds, rhoiptelol C (3), rhoiptelol B (4) and 3′,4″-epoxy-2-O-β-d-glucopyanosyl-1-(4-hydroxyphenyl)- 7-(3-methoxyphenyl)hepta ...
- DOI:
- 10.1080/14786419.2017.1408100
-
http://dx.doi.org/10.1080/14786419.2017.1408100
- Author:
- Zhang, Nenling; Tian, Birong; Zhao, Shuang; Zhang, Xu; Pan, Di; Shen, Xiangchun; Zhang, Yanyan
- Source:
- Natural product research 2019 v.33 no.5 pp. 617-621
- ISSN:
- 1478-6427
- Subject:
- Humulus lupulus; angiotensin II; cell viability; chalcone; human umbilical vein endothelial cells; nuclear magnetic resonance spectroscopy; protective effect; spectral analysis
- Abstract:
- ... One new formylated chalcone, 3′- formyl xanthohumol (1) was isolated from the EtOAc-soluble partition of the cones of Humulus lupulus, along with two other known chalcones, namely dehydrocycloxanthohumol (2) and xanthohumol (3). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR and MS data. The structures of the known compounds were identified by comparison of their spectro ...
- DOI:
- 10.1080/14786419.2017.1402318
-
http://dx.doi.org/10.1080/14786419.2017.1402318
- Author:
- Tran, Phi Hung; Le, Viet Dung; Do, Thi Ha; Nguyen, Thi Luyen; Nguyen, Phuong Thao; Nguyen, Trong Thong; Nguyen, Tien Dat
- Source:
- Natural product research 2019 v.33 no.5 pp. 695-700
- ISSN:
- 1478-6427
- Subject:
- Psychotria; aerial parts; bioactive properties; chemical composition; ethanol; inhibitory concentration 50; nitric oxide; spectroscopy
- Abstract:
- ... One new and three known compounds were isolated from the ethanol extract of Psychotria prainii aerial parts. By means of spectroscopic methods, their structures were elucidated to be deacetylasperulosidic acid 6-ethyl ether (1), asperulosidic acid (2), asperuloside (3) and obtucarbamates C (4). The isolated compounds were evaluated for their inhibitory effect on NO production in LPS-stimulated RAW ...
- DOI:
- 10.1080/14786419.2017.1408095
-
http://dx.doi.org/10.1080/14786419.2017.1408095
- Author:
- Ghania, Aissaoui; Nabila, Belyagoubi-Benhammou; Larbi, Belyagoubi; Elisabeth, Mouray; Philippe, Grellier; Mariem, Benmahdjoub; Khadidja, Kerzabi-Kanoun; Wacila, Benguedda-Rahal; Fawzia, Atik-Bekkara
- Source:
- Natural product research 2019 v.33 no.5 pp. 742-745
- ISSN:
- 1478-6427
- Subject:
- Bacillus cereus; Cladostephus; Plasmodium falciparum; Sargassum; Trypanosoma brucei brucei; algae; antiparasitic properties; blood flow; coasts; ethyl acetate; in vitro studies; inhibitory concentration 50; minimum inhibitory concentration; Algeria
- Abstract:
- ... The objective of this study was to investigate the biological activities of Algerian algae, Sargassum vulgare, Cladostephus hirsutus and Rissoella verruculosa. Antimicrobial activity of the crude extracts and their fractions was assessed using the disc diffusion assay, the minimum inhibitory concentration and the minimum bactericidal concentration. Antiparasitic activity was studied in vitro again ...
- DOI:
- 10.1080/14786419.2017.1405403
-
http://dx.doi.org/10.1080/14786419.2017.1405403
- Author:
- Lazare, Sidjui Sidjui; Désiré, Soh; Joel Ebenezer, Dameue Tegang; Brice, Happi Tchakounté; Rufin Marie, Toghueo Kouipou; Alain, Wembe Ngouonpe; Muhammad, Shaiq Ali; Gabriel, Folefoc Ngosong
- Source:
- Natural product research 2019 v.33 no.5 pp. 635-641
- ISSN:
- 1478-6427
- Subject:
- Guarea; cytotoxicity; fruits; human cell lines; inhibitory concentration 50; secondary metabolites; spectral analysis; triterpenoids
- Abstract:
- ... Two new seco-lanostane-type triterpenes, named mayomlactones A (1) and B (2) were isolated from the fruits of Leplaea mayombensis together with 10 known compounds (3–12). Structures of the new compounds were elucidated by extensive spectroscopic studies. Except compounds 11 and 12, all the other chemical compounds are newly reported from Leplaea genus. From the results of this investigation, compo ...
- DOI:
- 10.1080/14786419.2017.1402321
-
http://dx.doi.org/10.1080/14786419.2017.1402321
- Author:
- Duan, Jiang-Lian; Wu, Ya-Lu; Xu, Jian-Guo
- Source:
- Natural product research 2019 v.33 no.5 pp. 746-749
- ISSN:
- 1478-6427
- Subject:
- Isodon rubescens; antibacterial properties; bioactive compounds; flavonoids; freeze drying; phenolic compounds; vacuum drying
- Abstract:
- ... The influence of natural drying (ND), hot-air drying (HD), vacuum drying (VD), infrared drying (ID) and freeze drying (FD) on bioactive compounds and bioactivities of Isodon rubescens (Hemsl.) was investigated in this study. The results showed that different drying methods resulted in the differences in bioactive compositions’ content, antioxidant and antibacterial activities of extracts from I. r ...
- DOI:
- 10.1080/14786419.2017.1405416
-
http://dx.doi.org/10.1080/14786419.2017.1405416
- Author:
- Zhou, Xianli; Huang, Sixin; Wang, Pengcheng; Luo, Qin; Huang, Xiao; Xu, Qin; Qin, Jiangke; Liang, Chengqin; Chen, Xu
- Source:
- Natural product research 2019 v.33 no.5 pp. 681-686
- ISSN:
- 1478-6427
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Stachys; antioxidant activity; inhibitory concentration 50; iridoid glycosides; nuclear magnetic resonance spectroscopy; roots; syringic acid
- Abstract:
- ... A new derivative of syringic acid, stageobester A (1) and two iridoid glycosides which including a new one, stageoboside A (2), were isolated from the roots of Stachys geobombycis. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR and MS spectra. In addition, all the isolates were tested for their antioxidant capacity. Compounds 1 and 2 showed moderate ...
- DOI:
- 10.1080/14786419.2017.1405413
-
http://dx.doi.org/10.1080/14786419.2017.1405413
- Author:
- Bala, Manju; Kumar, Shiv; Pratap, Kunal; Verma, Praveen Kumar; Padwad, Yogendra; Singh, Bikram
- Source:
- Natural product research 2019 v.33 no.5 pp. 622-627
- ISSN:
- 1478-6427
- Subject:
- Cissampelos; butanol; chemical constituents of plants; chloroform; cytotoxicity; isoquinoline alkaloids; seasonal variation; wet season
- Abstract:
- ... The phytochemical and biological investigation of Cissampelos pareira leads to the isolation of one new isoquinoline alkaloid (7) along with six known isoquinoline alkaloids, namely, magnoflorine (1), magnocurarine (2), cissamine (3), curine (4), hayatinine (5) and cycleanine (6). Magnoflorine (1) and magnocurarine (2) were isolated for the first time from C. pareira. A new, rapid, simple and sens ...
- DOI:
- 10.1080/14786419.2017.1402319
-
http://dx.doi.org/10.1080/14786419.2017.1402319
- Author:
- Du, Jie; Wang, Chun-Hua; Yang, Jing; He, Xin; Han, Xiao-Liang; Li, Cong-Cong; Chai, Xin; Wang, Yue-Fei; Zhu, Yan; Li, Zheng
- Source:
- Natural product research 2019 v.33 no.5 pp. 673-680
- ISSN:
- 1478-6427
- Subject:
- Cullen corylifolium; chemical composition; flavonoids; fruits; human cell lines; in vitro studies; ionizing radiation; psoralen; radiation injury; radioprotective effect; spectral analysis
- Abstract:
- ... Two new flavonoids, corylifol F (1) and corylifol G (2), together with 19 known compounds, were isolated from the fruits of Psoralea corylifolia L.. The structures of these compounds were determined by interpretation of spectroscopic data and comparison with literature properties. The radioprotective effects of the isolated compounds against ionising radiation damage were also evaluated in vitro. ...
- DOI:
- 10.1080/14786419.2017.1405407
-
http://dx.doi.org/10.1080/14786419.2017.1405407
- Author:
- Oueslati, Med Habib; Bouajila, Jalloul; Belkacem, Med Amine; Harrath, Abdel Halim; Alwasel, Saleh H.; Ben Jannet, Hichem
- Source:
- Natural product research 2019 v.33 no.5 pp. 708-714
- ISSN:
- 1478-6427
- Subject:
- Ducrosia anethifolia; cell lines; cytotoxicity; elaidic acid; gas chromatography; methylene chloride; moieties; monoterpenoids; nuclear magnetic resonance spectroscopy; oleic acid; psoralens; secondary metabolites; seed oils; seeds; sesquiterpenoids; spectral analysis; stigmasterol; toxicity testing
- Abstract:
- ... Two new monoterpene Ducrosin A (1) and sesquiterpene Ducrosin B (2) were isolated along with three known compounds, stigmasterol (3) and two furanocoumarins (4 and 5), from the dichloromethane extract of the seeds of Ducrosia anethifolia (DC.) Boiss. Their structures were determined using extensive 1D and 2D NMR, (ES)-HRMS and IR spectroscopic analyses and by comparison with literature data. Gas c ...
- DOI:
- 10.1080/14786419.2017.1408101
-
http://dx.doi.org/10.1080/14786419.2017.1408101
- Author:
- Vinh, Le Ba; Nguyet, Nguyen Thi Minh; Yang, Seo Young; Kim, Jang Hoon; Thanh, Nguyen Van; Cuong, Nguyen Xuan; Nam, Nguyen Hoai; Minh, Chau Van; Hwang, Inkyu; Kim, Young Ho
- Source:
- Natural product research 2019 v.33 no.5 pp. 628-634
- ISSN:
- 1478-6427
- Subject:
- Aegiceras corniculatum; adenocarcinoma; breasts; cell lines; chromatography; colon; cytotoxicity; inhibitory concentration 50; leaves; melanoma; neoplasm cells; nuclear magnetic resonance spectroscopy; triterpenoid saponins
- Abstract:
- ... Using various chromatographic separations, sixteen compounds, including one new triterpene saponin named aegicoroside A (1), were isolated from the leaves of the Vietnamese mangrove Aegiceras corniculatum. Their structures were determined by spectroscopic methods such as 1D and 2D NMR and HR-ESI-MS. The cytotoxic activities of the isolated compounds against MCF7 (breast), HCT116 (colon), B16F10 (m ...
- DOI:
- 10.1080/14786419.2017.1402320
-
http://dx.doi.org/10.1080/14786419.2017.1402320
- Author:
- Sahnoun, Mouna; Bejar, Samir; Daoud, Lobna; Ayadi, Leila; Brini, Faiçal; Saibi, Walid
- Source:
- Natural product research 2019 v.33 no.5 pp. 755-758
- ISSN:
- 1478-6427
- Subject:
- Agave americana; Aspergillus oryzae; acarbose; alpha-amylase; biocatalysts; enzyme activity; humans; hyperglycemia; in vitro studies; inhibitory concentration 50; p-coumaric acid; starch; therapeutics
- Abstract:
- ... Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver–Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activity with an IC₅₀ of 98.8 μM which was about 2.3 times than acarbose. Puerarin (IC ...
- DOI:
- 10.1080/14786419.2017.1408094
-
http://dx.doi.org/10.1080/14786419.2017.1408094
- Author:
- Cong, Zhaoqing; Zhou, Man; Yang, Feifei; Liu, Chunyu; Pan, Ruile; Chang, Qi; Liu, Xinmin; Liao, Yonghong
- Source:
- Natural product research 2019 v.33 no.5 pp. 767-771
- ISSN:
- 1478-6427
- Subject:
- Ganoderma; Rhodiola; bioavailability; drugs; enzyme activity; glucuronosyltransferases; grape seed extract; grape seeds; models; rats; resveratrol
- Abstract:
- ... Herb extracts were shown to inhibit the activity of UDP-glucuronosyltransferases (UGTs) in vitro. However, the actual in vivo effect of the inhibitory ability on oral bioavailability is yet verified. In this study, resveratrol (RES) was used as a model drug to study the effect of three Chinese herb extracts, Ganoderma, Rhodiola and grape seed, on the in vitro and in vivo inhibition of glucuronidat ...
- DOI:
- 10.1080/14786419.2017.1408099
-
http://dx.doi.org/10.1080/14786419.2017.1408099
- Author:
- Fernandes, Eduardo Vignoto; Ramos, Aline Camargo; dos Santos, Alice Hartmann; Longhini, Renata; Gerardin, Daniela Cristina Cecatto; Venancio, Emerson José
- Source:
- Natural product research 2019 v.33 no.5 pp. 763-766
- ISSN:
- 1478-6427
- Subject:
- Trichilia catigua; aluminum hydroxide; antibodies; antibody formation; enzyme-linked immunosorbent assay; females; immunoglobulin G; immunoglobulin Y; males; maternal exposure; mothers; pregnancy; progeny; pups; rats
- Abstract:
- ... It was evaluated the effects of maternal treatment with the Trichilia catigua (ExTc) crude extract on the antibodies’ production by their offspring. Female rats received ExTc or saline from the first day of pregnancy until the twenty-first day after the birth of the pups, when the pups were weaned. All pups were inoculated with two doses of 50 μg of IgY diluted in aluminium hydroxide/PBS on days 2 ...
- DOI:
- 10.1080/14786419.2017.1408097
-
http://dx.doi.org/10.1080/14786419.2017.1408097
- Author:
- Cao, Haijing; Liu, Wenjing; Chang, Yuansen; Chen, Hui; Zhang, Yang; Xu, Wenping; Tao, Liming
- Source:
- Natural product research 2019 v.33 no.5 pp. 659-664
- ISSN:
- 1478-6427
- Subject:
- Mythimna separata; Streptomyces diastatochromogenes; insecticidal properties; lethal concentration 50; macrolides; spectroscopy
- Abstract:
- ... A new 24-membered macrolide, 5′-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insecticidal activity against oriental armyworm(Mythimna separata Walker) with LC₅₀ value ...
- DOI:
- 10.1080/14786419.2017.1405401
-
http://dx.doi.org/10.1080/14786419.2017.1405401
- Author:
- Li, Peng; Chen, Shi-yu; Shen, Shao-xin; Liu, Ling-xue; Xu, Jian-hua; Zhang, Zhi-qiang
- Source:
- Natural product research 2019 v.33 no.5 pp. 732-735
- ISSN:
- 1478-6427
- Subject:
- P-glycoproteins; cell cycle; drug therapy; multiple drug resistance; neoplasms; rhodamines; vincristine
- Abstract:
- ... Multidrug resistance is a major unresolved obstacle to successful cancer chemotherapy. It is often associated with an elevated efflux of a variety of anticancer drugs by ATP-binding cassette transporters including P-glycoprotein, BCRP and MRP1. In this study, the reversal effect of Ethyl lucidenates A on K562/A02 cells was investigated. At concentrations of 10 μM, Ethyl lucidenates A could reverse ...
- DOI:
- 10.1080/14786419.2017.1402323
-
http://dx.doi.org/10.1080/14786419.2017.1402323
- Author:
- Terzo, Simona; Baldassano, Sara; Caldara, Gaetano Felice; Ferrantelli, Vincenzo; Lo Dico, Gianluigi; Mulè, Flavia; Amato, Antonella
- Source:
- Natural product research 2019 v.33 no.5 pp. 715-726
- ISSN:
- 1478-6427
- Subject:
- anti-inflammatory activity; cardiovascular diseases; diet; energy content; gamma-tocopherol; glycemic control; lutein; noninsulin-dependent diabetes mellitus; nutrients; obesity; phytosterols; pistachios; potassium; unsaturated fatty acids
- Abstract:
- ... The health benefits of nuts, mainly in relation to the improvement of dysmetabolic conditions such as obesity, type 2 diabetes mellitus and the related cardiovascular diseases, have been widely demonstrated. Compared to other nuts, pistachios have a lower fat and caloric content, and contain the highest levels of unsaturated fatty acids, potassium, γ-tocopherol, phytosterols and xanthophyll carote ...
- DOI:
- 10.1080/14786419.2017.1408093
-
http://dx.doi.org/10.1080/14786419.2017.1408093
- Author:
- Zeng, Wen-Wen; Lai, Lih-Shiuh
- Source:
- Natural product research 2019 v.33 no.5 pp. 736-741
- ISSN:
- 1478-6427
- Subject:
- Asplenium nidus; birds; clinical trials; collagen; cosmetics; emulsions; fibroblasts; humans; mucilages; p-coumaric acid; skin (animal); tissue repair; water holding capacity
- Abstract:
- ... p-coumaric acid and fucose-rich polysaccharide have been studied for many bio-functions in skin including cutaneous protection from oxidative damage and antiageing, respectively, as well as wound healing. The physiological activities of various bird’s nest fern extracts (BNFE), containing considerable fucose-rich mucilage and p-coumaric acid, on fibroblast and human skin were first investigated. B ...
- DOI:
- 10.1080/14786419.2017.1405400
-
http://dx.doi.org/10.1080/14786419.2017.1405400
- Author:
- Albarracín, Lady T.; Delgado, Wilman; Cuca, Luis Enrique; Ávila, Mónica C.
- Source:
- Natural product research 2019 v.33 no.5 pp. 687-694
- ISSN:
- 1478-6427
- Subject:
- Colletotrichum; Lauraceae; antifungal properties; bark; chloroform; dodecanoic acid; ethanol; growth inhibitors; hexane; lactones; metabolites; minimum inhibitory concentration; plant pathogens; screening
- Abstract:
- ... In this work, screening of Lauraceae species for their antifungal activity against Collectotrichum tamarilloi was carried out and the ethanol extract derived from the bark of Endlicheria arenosa was found to be the best candidate. From the ethanolic extract of the bark of E. arenosa, the hexane and chloroform fractions were found to be active, from these five fatty acids were identified and two la ...
- DOI:
- 10.1080/14786419.2017.1408090
-
http://dx.doi.org/10.1080/14786419.2017.1408090
- Author:
- Nooreen, Zulfa; Kumar, Anant; Bawankule, Dnyaneshwar Umrao; Tandon, Sudeep; Ali, Mohd; Xuan, Tran Dang; Ahmad, Ateeque
- Source:
- Natural product research 2019 v.33 no.5 pp. 665-672
- ISSN:
- 1478-6427
- Subject:
- Zanthoxylum armatum; anti-inflammatory activity; benzene; chemical composition; chemical structure; dose response; fruits; interleukin-6; macrophages; mice; palmitic acid; phenylacetic acid; spectroscopy; tumor necrosis factor-alpha
- Abstract:
- ... Chemical investigations on the fruits of Zanthoxylum armatum Roxb. (Rutaceae) led to the isolation of two new constituents characterised as 2α-methyl-2β-ethylene-3β-isopropyl-cyclohexan-1β, 3α-diol (1) and phenol-O-β-D-arabinopyranosyl-4′-(3″, 7″, 11″, 15″-tetramethyl)-hexadecan-1″-oate (2) along with known compounds m-methoxy palmityloxy benzene (3), acetyl phenyl acetate (4), linoleiyl-O-α-D-xyl ...
- DOI:
- 10.1080/14786419.2017.1405404
-
http://dx.doi.org/10.1080/14786419.2017.1405404