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You searched for: Journal Natural product research Remove constraint Journal: Natural product research Publication Year 2019 Remove constraint Publication Year: 2019 Source 2019 v.33 no.8 Remove constraint Source: 2019 v.33 no.8
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1. A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties

Author:
Stanimirovic, Bojana; Vujovic, Dragan; Pejin, Boris; Popovic Djordjevic, Jelena; Maletic, Radojka; Raicevic, Petar; Tesic, Zivoslav
Source:
Natural product research 2019 v.33 no.8 pp. 1209-1213
ISSN:
1478-6427
Subject:
Alzheimer disease; aluminum; breeding; chromium; copper; dietary supplements; humans; ingredients; iron; lead; leaves; manganese; neurodegenerative diseases; nickel; potassium; sodium; toxicity; viticulture; zinc; Serbia
Abstract:
... The elemental profile of the leaf samples of three Cabernet Franc clone candidates recently developed in Serbia (Nos. 02, 010 and 012) obtained in the last phase of clonal selection was examined within this study by ICP-OES. Optimal content of Al, Fe, Cu and Zn, the metals well known for their links with a number of neurodegenerative disorders including Alzheimer’s disease, has actually highlighte ...
DOI:
10.1080/14786419.2018.1457671

2. A new flavonoid from the leaves of Atalantia monophylla (L.) DC

Author:
Posri, Priyapan; Suthiwong, Jittra; Takomthong, Pitchayakarn; Wongsa, Chatchawan; Chuenban, Chindawadee; Boonyarat, Chantana; Yenjai, Chavi
Source:
Natural product research 2019 v.33 no.8 pp. 1115-1121
ISSN:
1478-6427
Subject:
Alzheimer disease; Atalantia; acetylcholinesterase; antioxidant activity; flavonoids; hydroxybenzaldehyde; leaves
Abstract:
... A new flavonoid, atalantraflavone (1) as well as eight known compounds including atalantoflavone (2), racemoflavone (3), 5,4′-dihydroxy-(3″,4″-dihydro-3″,4″-dihydroxy)-2″,2″-dimethylpyrano-(5″,6″:7,8)-flavone (4), lupalbigenin (5), anabellamide (6), citrusinine I (7), p-hydroxybenzaldehyde (8), and frideline (9), were isolated from the leaves of Atalantia monophylla (L.) DC. Focusing on Alzheimer’ ...
DOI:
10.1080/14786419.2018.1457667

3. A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca

Author:
Hassan, Ahmed R.; Amer, Khadiga F.; El-Toumy, Sayed A.; Nielsen, John; Christensen, Søren Brøgger
Source:
Natural product research 2019 v.33 no.8 pp. 1135-1139
ISSN:
1478-6427
Subject:
Taverniera; aerial parts; formononetin; glycosides; isorhamnetin; kaempferol
Abstract:
... Isolation of flavonoids from the aerial parts of Taverniera aegyptiaca Bioss. (Fabaceae) led to identification of one new flavonol glycoside, isorhamnetin-3-O-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranoside (1), along with eleven compounds, which previously have not been isolated from this plant quercetin-3-O-α-l-rhamnopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranoside] (2), isorhamn ...
DOI:
10.1080/14786419.2018.1460834

4. A new galloyl glycoside from Lotus corniculatus

Author:
Zhao, Hongmei; Chen, Lijun; Yang, Yiyu; Zhang, Yan; Chen, Yegao
Source:
Natural product research 2019 v.33 no.8 pp. 1158-1161
ISSN:
1478-6427
Subject:
Lotus corniculatus; cytotoxicity; glucosides; humans; neoplasms; phenolic compounds; spectral analysis
Abstract:
... A new galloyl glucoside, 2,6-di-O-acetyl 1-O-galloyl β-D-glucose (1), along with five known phenolic compounds were isolated from the whole plants of Lotus corniculatus. Their structures were elucidated by means of extensive spectroscopic analysis. Compound 1 was assessed for its cytotoxicity against five human tumour lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that it ...
DOI:
10.1080/14786419.2018.1460839

5. A new guaiane sesquiterpene from cultures of the fungus Fulvifomes kanehirae

Author:
Ding, Jian-Hai; Li, Zheng-Hui; Feng, Tao; Liu, Ji-Kai
Source:
Natural product research 2019 v.33 no.8 pp. 1223-1226
ISSN:
1478-6427
Subject:
11-beta-hydroxysteroid dehydrogenase; fungi; isozymes; nuclear magnetic resonance spectroscopy; sesquiterpenoids
Abstract:
... A new guaiane sesquiterpene (1) was isolated from cultures of the fungus Fulvifomes kanehirae. Its structure was elucidated by spectroscopic methods including extensive 2D-NMR techniques. Meanwhile, the compound was tested for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases (11β-HSD). ...
DOI:
10.1080/14786419.2018.1463529

6. A new sterol from the Vietnamese marine sponge Xestospongia testudinaria and its biological activities

Author:
Nguyen, Hien Minh; Ito, Takuya; Win, Nwet Nwet; Vo, Hung Quoc; Nguyen, Hoai Thi; Morita, Hiroyuki
Source:
Natural product research 2019 v.33 no.8 pp. 1175-1181
ISSN:
1478-6427
Subject:
Porifera; breast neoplasms; chemical structure; cytotoxicity; fibroblasts; human cell lines; humans; inhibitory concentration 50; lung neoplasms; neoplasm cells; spectral analysis; sterols; uterine cervical neoplasms; Vietnam
Abstract:
... A new sterol, langcosterol A (1), together with two known sterols 2 and 3, were isolated from the marine sponge Xestospongia testudinaria collected in Vietnam. Their chemical structures were elucidated on the basis of extensive spectroscopic analyses and comparisons with published data. The new compound 1 and the known compound 3 exhibited moderate cytotoxic activities against three human cancer c ...
DOI:
10.1080/14786419.2018.1465057

7. Chemical composition of the essential oils from the aerial parts of two Malagasy endemic species (Apiaceae): Billburttia capensoides Sales & Hedge and Billburttia vaginoides Sales & Hedge

Author:
Rakotonandrasana, Stephan R.; Rabehaja, Delphin J. R.; Paoli, Mathieu; de Rocca Serra, Dominique; Andrianjara, Charles; Bighelli, Ange; Ramanoelina, Panja A. R.; Tomi, Félix
Source:
Natural product research 2019 v.33 no.8 pp. 1200-1203
ISSN:
1478-6427
Subject:
Apiaceae; aerial parts; chemical composition; dill; essential oils; gas chromatography-mass spectrometry; indigenous species; nuclear magnetic resonance spectroscopy; oils; sales; statistical analysis; terpinolene
Abstract:
... The chemical composition of twenty-five essential oil samples from the aerial parts of two Malagasy endemic species Billburttia capensoides Sales & Hedge and B. vaginoides Sales & Hedge, were investigated for the first time. Based on chromatographic profiles, three selected samples were investigated using GC(RI), GC-MS and ¹³C NMR. The content of the main components varied drastically from sample ...
DOI:
10.1080/14786419.2018.1457669

8. Chemical composition of the essential oils of Centaurea tomentella Hand.-Mazz. and C. haussknechtii Boiss. (Asteraceae) collected wild in Turkey and their activity on microorganisms affecting historical art craft

Author:
Bruno, Maurizio; Modica, Aurora; Catinella, Giorgia; Canlı, Cem; Arasoglu, Tülin; Çelik, Sezgin
Source:
Natural product research 2019 v.33 no.8 pp. 1092-1100
ISSN:
1478-6427
Subject:
Centaurea; aerial parts; antifungal properties; chemical composition; essential oils; gas chromatography-mass spectrometry; microorganisms; palmitic acid; spathulenol; Turkey (country)
Abstract:
... In the present study the chemical composition of the essential oils from aerial parts of Centaurea tomentella Hand.-Mazz. and C. haussknechtii Boiss. collected in Turkey was evaluated by GC and GC-MS. The main components of C. tomentella L. were hexadecanoic acid (19.7%), caryophyllene oxide (6.6%) and spathulenol (4.8%) whereas C. haussknechtii was rich in hexadecanoic acid (26.2%), (Z,Z)-9,12-oc ...
DOI:
10.1080/14786419.2018.1463531

9. Convergent synthesis of Carpatamide-A: Cytotoxic arylamine derivative from marine derived Streptomyces sp.

Author:
Burman, Rohani Prasad; Gupta, Shantanu; Bhatti, Jyoti; Verma, Krishan; Rajak, Devendra; Gill, Manjinder Singh
Source:
Natural product research 2019 v.33 no.8 pp. 1147-1157
ISSN:
1478-6427
Subject:
Streptomyces; benzaldehyde; cytotoxicity; demethylation; methylation
Abstract:
... First total synthesis of carpatamide-A 7a, cytotoxic arylamine derivative isolated from marine derived Streptomyces sp., was achieved in twelve steps with overall yield of 24% with seven longest linear steps. In the penultimate step, dienoic acid 13 and an amino-phenylpropionic acid methyl ester core 21 were coupled to synthesize methylated derivativative of carpatamide-A 22 followed by demethylat ...
DOI:
10.1080/14786419.2018.1460837

10. Development and validation of polar RP-HPLC method for screening for ectoine high-yield strains in marine bacteria with green chemistry

Author:
Chen, Jun; Chen, Jianwei; Wang, Sijia; Zhou, Guangmin; Chen, Danqing; Zhang, Huawei; Wang, Hong
Source:
Natural product research 2019 v.33 no.8 pp. 1122-1126
ISSN:
1478-6427
Subject:
aquatic bacteria; detection limit; green chemistry; reversed-phase high performance liquid chromatography; salinity; screening; solutes; temperature; wavelengths
Abstract:
... A novel, green, rapid, and precise polar RP-HPLC method has been successfully developed and screened for ectoine high-yield strain in marine bacteria. Ectoine is a polar and extremely useful solute which allows microorganisms to survive in extreme environmental salinity. This paper describes a polar-HPLC method employed polar RP-C18 (5 μm, 250 × 4.6 mm) using pure water as the mobile phase and a c ...
DOI:
10.1080/14786419.2018.1457668

11. Discovery of a new biphenyl derivative by epigenetic manipulation of marine-derived fungus Aspergillus versicolor

Author:
Zhu, Jing Xuan; Ding, Lijian; He, Shan
Source:
Natural product research 2019 v.33 no.8 pp. 1191-1195
ISSN:
1478-6427
Subject:
Aspergillus versicolor; Staphylococcus aureus; biphenyl; enzyme inhibitors; epigenetics; fungi; histone deacetylase; secondary metabolites; spectral analysis
Abstract:
... Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two known compounds, 2,4-dimethoxyphenol (2) and diorcinol (3) were isolated. The str ...
DOI:
10.1080/14786419.2018.1465423

12. Effects of ionizing radiation on bio-active plant extracts useful for preventing oxidative damages

Author:
Mulinacci, Nadia; Valletta, Alessio; Pasqualetti, Valentina; Innocenti, Marzia; Giuliani, Camilla; Bellumori, Maria; De Angelis, Giulia; Carnevale, Alessia; Locato, Vittoria; Di Venanzio, Cristina; De Gara, Laura; Pasqua, Gabriella
Source:
Natural product research 2019 v.33 no.8 pp. 1106-1114
ISSN:
1478-6427
Subject:
antioxidant activity; ascorbic acid; dietary supplements; humans; ionizing radiation; irradiation; oxidative stress; phenols; phytochemicals; plant byproducts; plant extracts; radiotherapy
Abstract:
... Humans are exposed to ionizing radiations in medical radiodiagnosis and radiotherapy that cause oxidative damages and degenerative diseases. Airplane pilots, and even more astronauts, are exposed to a variety of potentially harmful factors, including cosmic radiations. Among the phytochemicals, phenols are particularly efficient in countering the oxidative stress. In the present study, different e ...
DOI:
10.1080/14786419.2018.1457663

13. Four new phenolic constituents from the rhizomes of Gastrodia elata Blume

Author:
Wang, Zhi-Wei; Li, Yun; Liu, Da-Hui; Mu, Yan; Dong, Hong-Jing; Zhou, Hong-Lei; Guo, Lan-Ping; Wang, Xiao
Source:
Natural product research 2019 v.33 no.8 pp. 1140-1146
ISSN:
1478-6427
Subject:
Gastrodia elata; cell death; median effective concentration; neuroprotective effect; phenolic compounds; rhizomes
Abstract:
... Four new gastrodin derivatives containing a trans-cinnamoyl unit (1–4) and nine known compounds (5–13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC₅₀ values of 10.5 and 10.2 μM, respectively. ...
DOI:
10.1080/14786419.2018.1460836

14. Heptyl vicianoside and methyl caramboside from sour star fruit

Author:
Yang, Dan; Jia, Xuchao; Xie, Haihui
Source:
Natural product research 2019 v.33 no.8 pp. 1233-1236
ISSN:
1478-6427
Subject:
Averrhoa carambola; acetylcholinesterase; alpha-glucosidase; enzyme inhibition; fruits; glycosides; rutin; spectroscopy; triacylglycerol lipase
Abstract:
... Two new alkyl glycosides, heptyl vicianoside (1) and methyl 2-O-β-d-fucopyranosyl-α-l-arabinofuranoside (methyl caramboside, 4), were isolated from the sour fruit of Averrhoa carambola L. (Oxalidaceae), along with octyl vicianoside (2), cis-3-hexenyl rutinoside (3), and methyl α-d-fructofuranoside (5). Their structures were determined by spectroscopic and chemical methods. Compounds 2, 3, and 5 we ...
DOI:
10.1080/14786419.2018.1466123

15. Increased synthesis of a new oleanane-type saponin in hairy roots of marigold (Calendula officinalis) after treatment with jasmonic acid

Author:
Markowski, Michał; Długosz, Marek; Szakiel, Anna; Durli, Mathieu; Poinsignon, Sophie; Bouguet-Bonnet, Sabine; Vernex-Loset, Lionel; Krier, Gabriel; Henry, Max
Source:
Natural product research 2019 v.33 no.8 pp. 1218-1222
ISSN:
1478-6427
Subject:
Calendula officinalis; Rhizobium rhizogenes; biosynthesis; desmosides; flowers; glucosides; glycosylation; high performance liquid chromatography; indigenous species; jasmonic acid; matrix-assisted laser desorption-ionization mass spectrometry; moieties; nuclear magnetic resonance spectroscopy; oleanolic acid; plant stress; plants (botany); roots; sugars
Abstract:
... Native plant of marigold (Calendula officinalis L.) synthesizes oleanolic acid saponins classified as glucosides or glucuronides according to the first residue in sugar chain bound to C-3 hydroxyl group. Hairy root culture, obtained by transformation with Agrobacterium rhizogenes strain 15834, exhibit a potent ability of synthesis of oleanolic acid glycosides. The HPLC profile of saponin fraction ...
DOI:
10.1080/14786419.2018.1460840

16. Metabolism, transformation and dynamic changes of alkaloids in silkworm during feeding mulberry leaves

Author:
Zhang, Liwen; Bai, Yongliang; Su, Shulan; Ouyang, Zhen; Liu, Li; Pan, Gang; Qian, Dawei; Duan, Jinao
Source:
Natural product research 2019 v.33 no.8 pp. 1182-1190
ISSN:
1478-6427
Subject:
alkaloids; fagomine; instars; leaves; metabolism; mulberries; quantitative analysis; silkworms
Abstract:
... Metabolism, transformation and dynamic changes of DNJ, 2-O-α-D-Gal-DNJ, fagomine, isofagomine and 4-O-β-d-Glc-fagomine from mulberry leaves in silkworms at different instars were observed. UPLC-Q/TOF-MS and UPLC-TQ/MS methods were adopted for qualitative and quantitative analysis respectively. Three species mulberry leaves were used to feed the silkworm as controls. By analyzing and comparing the ...
DOI:
10.1080/14786419.2018.1465422

17. NMR-based metabolomics to evaluate the milk composition from Friesian and autochthonous cows of Northern Italy at different lactation times

Author:
Tomassini, A.; Curone, G.; Solè, M.; Capuani, G.; Sciubba, F.; Conta, G.; Miccheli, A.; Vigo, D.
Source:
Natural product research 2019 v.33 no.8 pp. 1085-1091
ISSN:
1478-6427
Subject:
biodiversity; breeds; cows; diet; farms; genetic background; industry; late lactation; metabolites; metabolomics; milk; milk composition; milk quality; nuclear magnetic resonance spectroscopy; nutritive value; races; Italy
Abstract:
... It is well established that different factors affect milk composition in cows and that milk composition, in turn, affect both technological and nutritional qualities. In this respect the comprehension of the metabolic variability of milk composition in relation to the lactation time as well as to the genetic background may be of paramount importance for the agri-food industries. In the present stu ...
DOI:
10.1080/14786419.2018.1462183

18. Optimized protocol for multigram preparation of emodin anthrone, a precursor in the hypericin synthesis

Author:
Gonçalves, Renato Sonchini; César, Gabriel Batista; Barbosa, Patrícia Magalhães; Hioka, Noboru; Nakamura, Celso Vataru; Bruschi, Marcos Luciano; Caetano, Wilker
Source:
Natural product research 2019 v.33 no.8 pp. 1196-1199
ISSN:
1478-6427
Subject:
Hypericum; emodin; hypericin; photosensitizing agents; reducing agents; screening; spectroscopy
Abstract:
... Emodin reduction to emodin anthrone comprise one of three process steps involved in the hypericin synthesis, a powerful natural photosensitiser found in plants of the genus Hypericum. In this communication, an optimized protocol was established for emodin reduction enabling an efficient multigram preparation of emodin anthrone. A screening of reducing agent (SnCl₂·2H₂O and HClcₒₙc) under different ...
DOI:
10.1080/14786419.2018.1457661

19. Phytochemical investigation on Myristica fragrans stem bark

Author:
Francis, Sajin K.; James, Beena; Varughese, Sunil; Nair, Mangalam S.
Source:
Natural product research 2019 v.33 no.8 pp. 1204-1208
ISSN:
1478-6427
Subject:
Myristica fragrans; bark; beta-sitosterol; crystal structure; lignans; spectroscopy; spices; tetrahydrofuran; India; Indonesia; South Africa; Sri Lanka
Abstract:
... Myristica fragrans Houtt., the source of very important spice ‘nutmeg’ used world over is native to India, Indonesia, Sri Lanka, South Africa and Southeast Asia. Phytochemical investigation of M. fragrans stem bark led to the isolation of bis-aryl dimethyl tetrahydrofuran lignans, such as grandisin [(7S,8S,7′S,8′S)-3,3′,4,4′,5,5′-hexamethoxy-7,7′,8,8′-lignan] and (7S,8S,7′R,8′R)-3,3′,4,4′,5,5′-hex ...
DOI:
10.1080/14786419.2018.1457670

20. Structurally diverse diterpenoids from Trigonostemon howii

Author:
Liu, Yan-Ping; Wen, Qing; Hu, Shi; Ma, Yan-Lei; Jiang, Zhi-Hua; Tang, Jin-Ying; Fu, Yan-Hui
Source:
Natural product research 2019 v.33 no.8 pp. 1169-1174
ISSN:
1478-6427
Subject:
cytotoxicity; diterpenoids; human cell lines; humans; inhibitory concentration 50; leaves; neoplasm cells; phytochemicals; spectroscopy; stems
Abstract:
... Phytochemical investigation on the stems and leaves of Trigonostemon howii resulted in the isolation of a new abietane diterpenoid, trigohowimine A (1), along with seven known structurally diverse diterpenoids (2–8). The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparison with data reported in the literature. New compound 1 was eva ...
DOI:
10.1080/14786419.2018.1462184