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- Yang, Liyuan; Lin, Jun; Zhou, Bin; Liu, Yangang; Zhu, Baoquan
- Natural product research 2017 v.31 no.4 pp. 487-491
- Hepatitis C virus; Taxillus; active ingredients; bioassays; enzyme activity; ethyl acetate; flavonoids; inhibitory concentration 50; serine proteinases
- ... This study aimed to isolate active compounds from traditional Chinese medicinal Taxillus sutchuenensis to inhibit hepatitis C virus (HCV) NS3 protease activity. Under the guidance of bioassay, 10 compounds were isolated from the EtOAc extract fraction, which were identified as inhibitors of HCV NS3 protease. IC ₅₀ values of these compounds were obtained, and a broad degree of anti-HCV activity was ...