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- Author:
- Agnihotri, Vasudha; Sati, Priyanka; Jantwal, Arvind; Pandey, Anita
- Source:
- Natural product research 2015 v.29 no.11 pp. 1074-1077
- ISSN:
- 1478-6427
- Subject:
- Bergenia; anti-infective properties; antioxidant activity; antioxidants; ethyl acetate; flavonoids; leaf extracts; maceration; medicinal plants; metabolites; methanol; microorganisms; minimum inhibitory concentration; phytopharmaceuticals; solvents
- Abstract:
- ... Phenolic and flavonoid contents in leaf extracts of Bergenia ligulata have been analysed for their contribution in antimicrobial and antioxidant activities. The extracts were prepared in three solvents (separately) following maceration and soxhelt methods. The antimicrobial activity was tested using disc diffusion assay against a range of microorganisms along with the determination of minimum inhi ...
- DOI:
- 10.1080/14786419.2014.980244
-
http://dx.doi.org/10.1080/14786419.2014.980244
- Author:
- Iqtedar, Mehwish; Nadeem, Mohammad; Naeem, Hira; Abdullah, Roheena; Naz, Shagufta; Syed, Qurat ul Ain; Kaleem, Afshan
- Source:
- Natural product research 2015 v.29 no.11 pp. 1012-1019
- ISSN:
- 1478-6427
- Subject:
- Saccharum spontaneum; Trichoderma viride; biomass; biotransformation; delignification; endo-1,4-beta-glucanase; ethanol production; industrialization; inoculum; lignocellulose; manganese; pH; polysorbates; saccharification; sodium hydroxide; submerged fermentation; surfactants
- Abstract:
- ... The industrialisation of lignocellulose conversion is impeded by expensive cellulase enzymes required for saccharification in bioethanol production. Current research undertakes cellulase production from pretreated Saccharum spontaneum through Trichoderma viride HN1 under submerged fermentation conditions. Pretreatment of substrate with 2% NaOH resulted in 88% delignification. Maximum cellulase pro ...
- DOI:
- 10.1080/14786419.2014.971320
-
http://dx.doi.org/10.1080/14786419.2014.971320
- Author:
- Khan, Rukaiyya Sirajuddin; Senthi, Mahibalan; Rao, Poorna Chandra; Basha, Ameer; Alvala, Mallika; Tummuri, Dinesh; Masubuti, Hironori; Fujimoto, Yoshinori; Begum, Ahil Sajeli
- Source:
- Natural product research 2015 v.29 no.11 pp. 1069-1073
- ISSN:
- 1478-6427
- Subject:
- Abutilon; active ingredients; cell viability; chloroform; cytotoxicity; ethyl acetate; high performance liquid chromatography; humans; leaves; methanol; syringic acid
- Abstract:
- ... The study was aimed to identify cytotoxic leads from Abutilon indicum leaves for treating glioblastoma. The petroleum ether extract, methanol extract (AIM), chloroform and ethyl acetate sub-fractions (AIM-C and AIM-E, respectively) prepared from AIM were tested for cytotoxicity on U87MG human glioblastoma cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. These extract ...
- DOI:
- 10.1080/14786419.2014.976643
-
http://dx.doi.org/10.1080/14786419.2014.976643
- Author:
- Kazemi, M.
- Source:
- Natural product research 2015 v.29 no.11 pp. 1065-1068
- ISSN:
- 1478-6427
- Subject:
- Aspergillus flavus; Aspergillus niger; Trachyspermum ammi; aflatoxin B1; antifungal properties; cherry tomatoes; dill; essential oils; food spoilage; fruits; fungi; mycelium; oils; seeds
- Abstract:
- ... The objectives of this study were to determine the antiaflatoxin B ₁ activity in vitro of the essential oil (EO) extracted from the seeds of Carum copticum and to evaluate its antifungal activity in vivo as a potential food preservative. The C. copticum EO exhibited noticeable inhibition on dry mycelium and synthesis of aflatoxin B ₁ (AFB ₁) by Aspergillus flavus , completely inhibiting AFB ₁ prod ...
- DOI:
- 10.1080/14786419.2014.971796
-
http://dx.doi.org/10.1080/14786419.2014.971796
- Author:
- Abdullah, Roheena; Nisar, Kinza; Aslam, Aafia; Iqtedar, Mehwish; Naz, Shagufta
- Source:
- Natural product research 2015 v.29 no.11 pp. 1006-1011
- ISSN:
- 1478-6427
- Subject:
- Aspergillus niger; agar; ammonium sulfate; carbon; fungi; glucose; nitrogen; pH; solid state fermentation; temperature; wheat bran; xylan; xylanases; yeast extract
- Abstract:
- ... This study is related to the isolation of fungal strain for xylanase production using agro-industrial residues. Forty fungal strains with xylanolytic potential were isolated by using xylan agar plates and quantitatively screened in solid-state fermentation. Of all the tested isolates, the strain showing highest ability to produce xylanase was assigned the code Aspergillus niger LCBT-14. For the en ...
- DOI:
- 10.1080/14786419.2014.968157
-
http://dx.doi.org/10.1080/14786419.2014.968157
- Author:
- Das, Saibal; Bandyopadhyay, Sanjib; Ramasamy, Anand; Mondal, Somnath
- Source:
- Natural product research 2015 v.29 no.11 pp. 1059-1064
- ISSN:
- 1478-6427
- Subject:
- Basella alba; acetaminophen; alkaline phosphatase; analysis of variance; bilirubin; blood serum; hepatoprotective effect; hepatotoxicity; histopathology; leaf extracts; leaves; liver; proteins; rats; silymarin
- Abstract:
- ... This study was done to evaluate possible hepatoprotective effects of aqueous leaf extracts of Basella alba in comparison with silymarin in paracetamol-induced hepatotoxicity in albino rats. Six groups of six albino rats each received orally for 6 weeks, vehicle, paracetamol (2 g/kg/day), paracetamol (2 g/kg/day) plus silymarin (50 mg/kg/day), paracetamol (2 g/kg/day) plus B. alba extract (60 mg/kg ...
- DOI:
- 10.1080/14786419.2014.971795
-
http://dx.doi.org/10.1080/14786419.2014.971795
- Author:
- Yousaf, Zubaida; Hu, Weiming; Zhang, Yanjun; Zeng, Shaohua; Wang, Ying
- Source:
- Natural product research 2015 v.29 no.11 pp. 1020-1025
- ISSN:
- 1478-6427
- Subject:
- Epimedium; alleles; economic valuation; genetic variation; heterozygosity; loci; microsatellite repeats
- Abstract:
- ... Epimedium species has gained prime importance due to their medicinal and economic values. Therefore, in this study, 26 genomic SSR and 10 EST-SSR markers were developed for 13 medicinal species of the Epimedium genus and one out-group species Vancouveria hexandra W. J. Hooker to explore the existing genetic diversity. A total of 100 alleles by genomic SSR and 65 by EST-SSR were detected. The genom ...
- DOI:
- 10.1080/14786419.2014.979419
-
http://dx.doi.org/10.1080/14786419.2014.979419
- Author:
- Gelmini, F.; Squillace, P.; Testa, C.; Sparacino, A.C.; Angioletti, S.; Beretta, G.
- Source:
- Natural product research 2015 v.29 no.11 pp. 993-998
- ISSN:
- 1478-6427
- Subject:
- Candida albicans; Escherichia coli; Plectranthus barbatus; anti-infective properties; distillation; essential oils; gas chromatography-mass spectrometry; iron; leaves; roots; steam; stems; Italy
- Abstract:
- ... Essential oils (EOs) from the roots, stems and leaves of Plectranthus barbatus (A) and Plectranthus caninus (B), cultivated in north Italy, were obtained by steam distillation and chemically characterised by gas chromatography–mass spectrometry. The highest yields were obtained from roots (268.15 and 673.60 mg/kg from A and B), followed by leaves (64.34 and 26.65 mg/kg) and stems (19.76 and 18.63 ...
- DOI:
- 10.1080/14786419.2014.965166
-
http://dx.doi.org/10.1080/14786419.2014.965166
- Author:
- Su, Jingqian; Yang, Minhe
- Source:
- Natural product research 2015 v.29 no.11 pp. 1035-1041
- ISSN:
- 1478-6427
- Subject:
- Alzheimer disease; Huperzia serrata; Paecilomyces; alkaloids; culture media; endophytes; fermentation; fungi; high performance liquid chromatography; mass spectrometry; models; screening; therapeutics; thin layer chromatography
- Abstract:
- ... Huperzine A (HupA), a naturally occurring alkaloid in the plant family Huperziaceae, has drawn great interest for its potential application in Alzheimer disease therapy. Our primary objective was to identify alkaloid- and HupA-producing fungi from the Chinese folk herb, Huperzia serrata . We established a rapid and efficient model for screening HupA-producing endophytic fungal strains. The presenc ...
- DOI:
- 10.1080/14786419.2014.980245
-
http://dx.doi.org/10.1080/14786419.2014.980245
- Author:
- Cho, Jin-Gyeong; Huh, Jeongran; Jeong, Rak-Hun; Cha, Byeong-Ju; Shrestha, Sabina; Lee, Dong-Geol; Kang, Hee-Cheol; Kim, Ji-Young; Baek, Nam-In
- Source:
- Natural product research 2015 v.29 no.11 pp. 1052-1054
- ISSN:
- 1478-6427
- Subject:
- Oryza sativa; melanin; melanoma; mice; quantitative analysis; roots; spectroscopy; tryptamine; vanillin
- Abstract:
- ... Five phenyl compounds, vanillin (1), methyl trans -ferulate (2), trans - p -coumaric acid methyl ester (3), N -benzoyltryptamine (4), and N -(trans -cinnamoyl)tryptamine (5), were isolated from the roots of Oryza sativa L. and identified on the basis of spectroscopic data. Compounds 3 and 5 showed strong inhibition effect on melanin production in murine B16-F10 melanoma cells and tyrosinase activi ...
- DOI:
- 10.1080/14786419.2014.968155
-
http://dx.doi.org/10.1080/14786419.2014.968155
- Author:
- Ombra, Maria Neve; Fratianni, Florinda; Granese, Tiziana; Cardinale, Federica; Cozzolino, Autilia; Nazzaro, Filomena
- Source:
- Natural product research 2015 v.29 no.11 pp. 1087-1091
- ISSN:
- 1478-6427
- Subject:
- Bacillus cereus; Escherichia coli; Pseudomonas aeruginosa; Solanum tuberosum; anti-infective properties; antioxidant activity; antioxidants; breast neoplasms; colorectal neoplasms; cooking; digestion; gastrointestinal system; gastrointestinal transit; human cell lines; human health; humans; neoplasm cells; potatoes
- Abstract:
- ... Analyses of antioxidant and in vitro antimicrobial and anti-proliferative activities of anthocyanin-rich extracts from purple potatoes, Solanum tuberosum L. cv Vitelotte noire (Solanaceae), were performed by simulating both a domestic cooking process and human digestion. Extracts of crude and cooked purple potato did not exhibit antimicrobial activity against the tester strains: Bacillus cereus , ...
- DOI:
- 10.1080/14786419.2014.981183
-
http://dx.doi.org/10.1080/14786419.2014.981183
- Author:
- Rajesh, P.S.; Samaga, Pradeepa V.; Ravishankar Rai, V.; Lokanatha Rai, K.M.
- Source:
- Natural product research 2015 v.29 no.11 pp. 1042-1045
- ISSN:
- 1478-6427
- Subject:
- Staphylococcus epidermidis; antioxidant activity; chelation; free radical scavengers; hexane; hydrogen peroxide; nuclear magnetic resonance spectroscopy
- Abstract:
- ... In this study, antimicrobial and antioxidant activities of the hexane extract of the root of Ventilago madraspatana were evaluated. Based on the significant bioactivity of crude hexane extract, an active compound was purified from the root extract. The active compound was further purified and identified as aromodendrin-4′-methyl ether by the ¹H NMR spectrum. The isolated compound significantly inh ...
- DOI:
- 10.1080/14786419.2014.968152
-
http://dx.doi.org/10.1080/14786419.2014.968152
- Author:
- Alvarenga, Tavane A.; Bertanha, Camila S.; de Oliveira, Pollyanna F.; Tavares, Denise C.; Gimenez, Valéria M.M.; Silva, Márcio L.A.; Cunha, Wilson R.; Januário, Ana H.; Pauletti, Patrícia M.
- Source:
- Natural product research 2015 v.29 no.11 pp. 1083-1086
- ISSN:
- 1478-6427
- Subject:
- fractionation; linoleate 13S-lipoxygenase; verbascoside; Cuspidaria; aerial parts; toxicity
- Abstract:
- ... This work evaluated the in vitro inhibitory activity of the crude ethanolic extract from the aerial parts of Cuspidaria pulchra (Cham.) L.G. Lohmann against 15-lipoxygenase (15-LOX). The bioassay-guided fractionation of the n -butanol fraction, which displayed the highest activity, led to the isolation of three compounds: caffeoylcalleryanin (1), verbascoside (2) and 6-hydroxyluteolin-7- O -β-gluc ...
- DOI:
- 10.1080/14786419.2014.981182
-
http://dx.doi.org/10.1080/14786419.2014.981182
- Author:
- Xu, Yuqing; Zhang, Jingzheng; Liu, Jing; Li, Sai; Li, Cheng; Wang, Wen; Ma, Rong; Liu, Yi
- Source:
- Natural product research 2015 v.29 no.11 pp. 1078-1082
- ISSN:
- 1478-6427
- Subject:
- anti-inflammatory activity; antioxidants; chromium; creatinine; inflammation; kidneys; luteolin; mice; mitogen-activated protein kinase; models; oxidative stress; phosphorylation; protective effect; urea nitrogen
- Abstract:
- ... Luteolin is reported to have antioxidant and anti-inflammatory properties. In this study, we investigated the protective effect of luteolin against the renal damage induced by d -galactose (d -gal). The levels of creatinine (Cr) and urea nitrogen (BUN) were evaluated in plasma, kidney sections were stained with haematoxylin–eosin, followed by assessment of the antioxidant and anti-inflammatory act ...
- DOI:
- 10.1080/14786419.2014.981181
-
http://dx.doi.org/10.1080/14786419.2014.981181
- Author:
- Jasamai, Malina; Jalil, Juriyati; Jantan, Ibrahim
- Source:
- Natural product research 2015 v.29 no.11 pp. 1055-1058
- ISSN:
- 1478-6427
- Subject:
- Ardisia; Clusiaceae; antagonists; bioactive properties; computer software; mechanism of action; molecular models; platelet-activating factor; screening
- Abstract:
- ... A handful of bioactive compounds from plants have been reported to possess platelet-activating factor (PAF) antagonist activity. However, their mode of action is not well understood. Selected bioactive compounds that exhibit PAF antagonist activity and synthetic PAF antagonists were subjected to docking simulations using the MOE 2007.09 software package. The docking study of PAF antagonists was ca ...
- DOI:
- 10.1080/14786419.2014.971317
-
http://dx.doi.org/10.1080/14786419.2014.971317
- Author:
- Kernéis, Sophie; Swift, Lucy H.; Lewis, Cody W.; Bruyère, Céline; Oumata, Nassima; Colas, Pierre; Ruchaud, Sandrine; Bain, John; Golsteyn, Roy M.
- Source:
- Natural product research 2015 v.29 no.11 pp. 1026-1034
- ISSN:
- 1478-6427
- Subject:
- Thermopsis; anticarcinogenic activity; beans; brain; buffaloes; cell adhesion; cell cycle; cell death; colon; cytotoxicity; ecological zones; flora; human cell lines; Canada
- Abstract:
- ... Many plant species within the terrestrial ecological zones of Canada have not yet been investigated for anti-cancer activity. We examined the scientific literature describing the endemic flora from the prairie ecological zone and selected the species, Thermopsis rhombifolia , locally known as the buffalo bean, for investigation of its anti-cancer potential. We tested it in cell-based assays using ...
- DOI:
- 10.1080/14786419.2014.979423
-
http://dx.doi.org/10.1080/14786419.2014.979423
- Author:
- Ayyathan, Dhanoop Manikoth; Chandrasekaran, Rajasekaran; Thiagarajan, Kalaivani
- Source:
- Natural product research 2015 v.29 no.11 pp. 1046-1051
- ISSN:
- 1478-6427
- Subject:
- brain; catalase; drugs; enzyme activity; flavonoids; glutathione; high performance liquid chromatography; methylmercury compounds; neuroprotective effect; oxidative stress; phenols; rats; saponins; thiobarbituric acid-reactive substances; toxicity; viability
- Abstract:
- ... The present study evaluates the neuroprotective effect of Brahmi against methyl mercury (MeHg) toxicity. The results demonstrated that MeHg-decreased mitochondrial viability in MTT assay and IC ₅₀ value was found to be 2.5 μg/mL. However, Brahmi at 250 μg/mL concentration effectively prevented mitochondrial damage caused by MeHg in MTT assay. Our results also demonstrated MeHg significantly inhibi ...
- DOI:
- 10.1080/14786419.2014.968153
-
http://dx.doi.org/10.1080/14786419.2014.968153
- Author:
- Baananou, Sameh; Bagdonaite, Edita; Marongiu, Bruno; Piras, Alessandra; Porcedda, Silvia; Falconieri, Danilo; Boughattas, Naceur A.
- Source:
- Natural product research 2015 v.29 no.11 pp. 999-1005
- ISSN:
- 1478-6427
- Subject:
- Rhododendron tomentosum; aerial parts; animals; anti-inflammatory activity; carbon dioxide; carrageenan; chemical composition; edema; essential oils; gas chromatography-mass spectrometry; ketoprofen; oils; sodium chloride; statistical analysis; supercritical fluid extraction
- Abstract:
- ... The anti-inflammatory activity of two extracts from the aerial parts of Ledum palustre has been reported. The volatile oil was obtained by supercritical fluid extraction (SFE) and the essential oil by hydrodistillation (HD). The oils were analysed by gas chromatography–mass spectrometry to monitor their composition. Both extracts shared as main compound (41.0–43.4%) ledol (23.3–26.7%) and ascarido ...
- DOI:
- 10.1080/14786419.2014.965167
-
http://dx.doi.org/10.1080/14786419.2014.965167