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You searched for: Journal Natural product research Remove constraint Journal: Natural product research Publication year rev 7985-2015 Remove constraint Publication year rev: 7985-2015 Source 2015 v.29 no.11 Remove constraint Source: 2015 v.29 no.11
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1. Antimicrobial and antioxidant phytochemicals in leaf extracts of Bergenia ligulata: a Himalayan herb of medicinal value

Author:
Vasudha Agnihotri; Priyanka Sati; Arvind Jantwal; Anita Pandey
Source:
Natural product research 2015 v.29 no.11 pp. 1074-1077
ISSN:
1478-6427
Subject:
Bergenia; anti-infective properties; antioxidant activity; antioxidants; ethyl acetate; flavonoids; leaf extracts; maceration; medicinal plants; metabolites; methanol; microorganisms; minimum inhibitory concentration; phytopharmaceuticals; solvents
Abstract:
... Phenolic and flavonoid contents in leaf extracts of Bergenia ligulata have been analysed for their contribution in antimicrobial and antioxidant activities. The extracts were prepared in three solvents (separately) following maceration and soxhelt methods. The antimicrobial activity was tested using disc diffusion assay against a range of microorganisms along with the determination of minimum inhi ...
DOI:
10.1080/14786419.2014.980244

2. Bioconversion potential of Trichoderma viride HN1 cellulase for a lignocellulosic biomass Saccharum spontaneum

Author:
Mehwish Iqtedar; Mohammad Nadeem; Hira Naeem; Roheena Abdullah; Shagufta Naz; Qurat ul Ain Syed; Afshan Kaleem
Source:
Natural product research 2015 v.29 no.11 pp. 1012-1019
ISSN:
1478-6427
Subject:
Saccharum spontaneum; Trichoderma viride; biomass; biotransformation; delignification; endo-1,4-beta-glucanase; ethanol production; industrialization; inoculum; lignocellulose; manganese; pH; polysorbates; saccharification; sodium hydroxide; submerged fermentation; surfactants
Abstract:
... The industrialisation of lignocellulose conversion is impeded by expensive cellulase enzymes required for saccharification in bioethanol production. Current research undertakes cellulase production from pretreated Saccharum spontaneum through Trichoderma viride HN1 under submerged fermentation conditions. Pretreatment of substrate with 2% NaOH resulted in 88% delignification. Maximum cellulase pro ...
DOI:
10.1080/14786419.2014.971320

3. Cytotoxic constituents of Abutilon indicum leaves against U87MG human glioblastoma cells

Author:
Rukaiyya Sirajuddin Khan; Mahibalan Senthi; Poorna Chandra Rao; Ameer Basha; Mallika Alvala; Dinesh Tummuri; Hironori Masubuti; Yoshinori Fujimoto; Ahil Sajeli Begum
Source:
Natural product research 2015 v.29 no.11 pp. 1069-1073
ISSN:
1478-6427
Subject:
Abutilon; active ingredients; cell viability; chloroform; cytotoxicity; ethyl acetate; high performance liquid chromatography; humans; leaves; methanol; syringic acid
Abstract:
... The study was aimed to identify cytotoxic leads from Abutilon indicum leaves for treating glioblastoma. The petroleum ether extract, methanol extract (AIM), chloroform and ethyl acetate sub-fractions (AIM-C and AIM-E, respectively) prepared from AIM were tested for cytotoxicity on U87MG human glioblastoma cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. These extract ...
DOI:
10.1080/14786419.2014.976643

4. Effect of Carum copticum essential oil on growth and aflatoxin formation by Aspergillus strains

Author:
M. Kazemi
Source:
Natural product research 2015 v.29 no.11 pp. 1065-1068
ISSN:
1478-6427
Subject:
Aspergillus flavus; Aspergillus niger; Trachyspermum ammi; aflatoxin B1; antifungal properties; cherry tomatoes; dill; essential oils; food spoilage; fruits; fungi; mycelium; oils; seeds
Abstract:
... The objectives of this study were to determine the antiaflatoxin B ₁ activity in vitro of the essential oil (EO) extracted from the seeds of Carum copticum and to evaluate its antifungal activity in vivo as a potential food preservative. The C. copticum EO exhibited noticeable inhibition on dry mycelium and synthesis of aflatoxin B ₁ (AFB ₁) by Aspergillus flavus , completely inhibiting AFB ₁ prod ...
DOI:
10.1080/14786419.2014.971796

5. Enhanced production of xylanase from locally isolated fungal strain using agro-industrial residues under solid-state fermentation

Author:
Roheena Abdullah; Kinza Nisar; Aafia Aslam; Mehwish Iqtedar; Shagufta Naz
Source:
Natural product research 2015 v.29 no.11 pp. 1006-1011
ISSN:
1478-6427
Subject:
Aspergillus niger; agar; ammonium sulfate; carbon; fungi; glucose; nitrogen; pH; solid state fermentation; temperature; wheat bran; xylan; xylanases; yeast extract
Abstract:
... This study is related to the isolation of fungal strain for xylanase production using agro-industrial residues. Forty fungal strains with xylanolytic potential were isolated by using xylan agar plates and quantitatively screened in solid-state fermentation. Of all the tested isolates, the strain showing highest ability to produce xylanase was assigned the code Aspergillus niger LCBT-14. For the en ...
DOI:
10.1080/14786419.2014.968157

6. Evaluation of hepatoprotective activity of aqueous extracts of leaves of Basella alba in albino rats

Author:
Saibal Das; Sanjib Bandyopadhyay; Anand Ramasamy; Somnath Mondal
Source:
Natural product research 2015 v.29 no.11 pp. 1059-1064
ISSN:
1478-6427
Subject:
Basella alba; acetaminophen; alkaline phosphatase; analysis of variance; bilirubin; blood serum; hepatoprotective effect; hepatotoxicity; histopathology; leaf extracts; leaves; liver; proteins; rats; silymarin
Abstract:
... This study was done to evaluate possible hepatoprotective effects of aqueous leaf extracts of Basella alba in comparison with silymarin in paracetamol-induced hepatotoxicity in albino rats. Six groups of six albino rats each received orally for 6 weeks, vehicle, paracetamol (2 g/kg/day), paracetamol (2 g/kg/day) plus silymarin (50 mg/kg/day), paracetamol (2 g/kg/day) plus B. alba extract (60 mg/kg ...
DOI:
10.1080/14786419.2014.971795

7. Exploration of genetic diversity among medicinally important genus Epimedium species based on genomic and EST-SSR marker

Author:
Zubaida Yousaf; Weiming Hu; Yanjun Zhang; Shaohua Zeng; Ying Wang
Source:
Natural product research 2015 v.29 no.11 pp. 1020-1025
ISSN:
1478-6427
Subject:
Epimedium; alleles; economic valuation; genetic variation; heterozygosity; loci; microsatellite repeats
Abstract:
... Epimedium species has gained prime importance due to their medicinal and economic values. Therefore, in this study, 26 genomic SSR and 10 EST-SSR markers were developed for 13 medicinal species of the Epimedium genus and one out-group species Vancouveria hexandra W. J. Hooker to explore the existing genetic diversity. A total of 100 alleles by genomic SSR and 65 by EST-SSR were detected. The genom ...
DOI:
10.1080/14786419.2014.979419

8. GC–MS characterisation and biological activity of essential oils from different vegetative organs of Plectranthus barbatus and Plectranthus caninus cultivated in north Italy

Author:
F. Gelmini; P. Squillace; C. Testa; A.C. Sparacino; S. Angioletti; G. Beretta
Source:
Natural product research 2015 v.29 no.11 pp. 993-998
ISSN:
1478-6427
Subject:
Candida albicans; Escherichia coli; Plectranthus barbatus; anti-infective properties; distillation; essential oils; gas chromatography-mass spectrometry; iron; leaves; roots; steam; stems; Italy
Abstract:
... Essential oils (EOs) from the roots, stems and leaves of Plectranthus barbatus (A) and Plectranthus caninus (B), cultivated in north Italy, were obtained by steam distillation and chemically characterised by gas chromatography–mass spectrometry. The highest yields were obtained from roots (268.15 and 673.60 mg/kg from A and B), followed by leaves (64.34 and 26.65 mg/kg) and stems (19.76 and 18.63  ...
DOI:
10.1080/14786419.2014.965166

9. Huperzine A production by Paecilomyces tenuis YS-13, an endophytic fungus isolated from Huperzia serrata

Author:
Jingqian Su; Minhe Yang
Source:
Natural product research 2015 v.29 no.11 pp. 1035-1041
ISSN:
1478-6427
Subject:
Alzheimer disease; Huperzia serrata; Paecilomyces; alkaloids; culture media; endophytes; fermentation; fungi; high performance liquid chromatography; mass spectrometry; models; screening; therapeutics; thin layer chromatography
Abstract:
... Huperzine A (HupA), a naturally occurring alkaloid in the plant family Huperziaceae, has drawn great interest for its potential application in Alzheimer disease therapy. Our primary objective was to identify alkaloid- and HupA-producing fungi from the Chinese folk herb, Huperzia serrata . We established a rapid and efficient model for screening HupA-producing endophytic fungal strains. The presenc ...
DOI:
10.1080/14786419.2014.980245

10. In vitro antioxidant, antimicrobial and anti-proliferative activities of purple potato extracts (Solanum tuberosum cv Vitelotte noire) following simulated gastro-intestinal digestion

Author:
Maria Neve Ombra; Florinda Fratianni; Tiziana Granese; Federica Cardinale; Autilia Cozzolino; Filomena Nazzaro
Source:
Natural product research 2015 v.29 no.11 pp. 1087-1091
ISSN:
1478-6427
Subject:
Bacillus cereus; Escherichia coli; Pseudomonas aeruginosa; Solanum tuberosum; anti-infective properties; antioxidant activity; antioxidants; breast neoplasms; colorectal neoplasms; cooking; digestion; gastrointestinal system; gastrointestinal transit; human cell lines; human health; humans; neoplasm cells; potatoes
Abstract:
... Analyses of antioxidant and in vitro antimicrobial and anti-proliferative activities of anthocyanin-rich extracts from purple potatoes, Solanum tuberosum L. cv Vitelotte noire (Solanaceae), were performed by simulating both a domestic cooking process and human digestion. Extracts of crude and cooked purple potato did not exhibit antimicrobial activity against the tester strains: Bacillus cereus , ...
DOI:
10.1080/14786419.2014.981183

11. In vitro biological activity of aromadendrin-4′-methyl ether isolated from root extract of Ventilago madraspatana Gaertn with relevance to anticandidal activity

Author:
P.S. Rajesh; Pradeepa V. Samaga; V. Ravishankar Rai; K.M. Lokanatha Rai
Source:
Natural product research 2015 v.29 no.11 pp. 1042-1045
ISSN:
1478-6427
Subject:
Staphylococcus epidermidis; antioxidant activity; chelation; free radical scavengers; hexane; hydrogen peroxide; nuclear magnetic resonance spectroscopy
Abstract:
... In this study, antimicrobial and antioxidant activities of the hexane extract of the root of Ventilago madraspatana were evaluated. Based on the significant bioactivity of crude hexane extract, an active compound was purified from the root extract. The active compound was further purified and identified as aromodendrin-4′-methyl ether by the ¹H NMR spectrum. The isolated compound significantly inh ...
DOI:
10.1080/14786419.2014.968152

12. Inhibition effect of phenyl compounds from the Oryza sativa roots on melanin production in murine B16-F10 melanoma cells

Author:
Jin-Gyeong Cho; Jeongran Huh; Rak-Hun Jeong; Byeong-Ju Cha; Sabina Shrestha; Dong-Geol Lee; Hee-Cheol Kang; Ji-Young Kim; Nam-In Baek
Source:
Natural product research 2015 v.29 no.11 pp. 1052-1054
ISSN:
1478-6427
Subject:
Oryza sativa; melanin; melanoma; mice; quantitative analysis; roots; spectroscopy; tryptamine; vanillin
Abstract:
... Five phenyl compounds, vanillin (1), methyl trans -ferulate (2), trans - p -coumaric acid methyl ester (3), N -benzoyltryptamine (4), and N -(trans -cinnamoyl)tryptamine (5), were isolated from the roots of Oryza sativa L. and identified on the basis of spectroscopic data. Compounds 3 and 5 showed strong inhibition effect on melanin production in murine B16-F10 melanoma cells and tyrosinase activi ...
DOI:
10.1080/14786419.2014.968155

13. Lipoxygenase inhibitory activity of Cuspidaria pulchra and isolated compounds

Author:
Tavane A. Alvarenga; Camila S. Bertanha; Pollyanna F. de Oliveira; Denise C. Tavares; Valéria M.M. Gimenez; Márcio L.A. Silva; Wilson R. Cunha; Ana H. Januário; Patrícia M. Pauletti
Source:
Natural product research 2015 v.29 no.11 pp. 1083-1086
ISSN:
1478-6427
Subject:
fractionation; linoleate 13S-lipoxygenase; verbascoside; Cuspidaria; aerial parts; toxicity
Abstract:
... This work evaluated the in vitro inhibitory activity of the crude ethanolic extract from the aerial parts of Cuspidaria pulchra (Cham.) L.G. Lohmann against 15-lipoxygenase (15-LOX). The bioassay-guided fractionation of the n -butanol fraction, which displayed the highest activity, led to the isolation of three compounds: caffeoylcalleryanin (1), verbascoside (2) and 6-hydroxyluteolin-7- O -β-gluc ...
DOI:
10.1080/14786419.2014.981182

14. Luteolin attenuate the d-galactose-induced renal damage by attenuation of oxidative stress and inflammation

Author:
Yuqing Xu; Jingzheng Zhang; Jing Liu; Sai Li; Cheng Li; Wen Wang; Rong Ma; Yi Liu
Source:
Natural product research 2015 v.29 no.11 pp. 1078-1082
ISSN:
1478-6427
Subject:
anti-inflammatory activity; antioxidants; chromium; creatinine; inflammation; kidneys; luteolin; mice; mitogen-activated protein kinase; models; oxidative stress; phosphorylation; protective effect; urea nitrogen
Abstract:
... Luteolin is reported to have antioxidant and anti-inflammatory properties. In this study, we investigated the protective effect of luteolin against the renal damage induced by d -galactose (d -gal). The levels of creatinine (Cr) and urea nitrogen (BUN) were evaluated in plasma, kidney sections were stained with haematoxylin–eosin, followed by assessment of the antioxidant and anti-inflammatory act ...
DOI:
10.1080/14786419.2014.981181

15. Molecular docking study on platelet-activating factor antagonistic activity of bioactive compounds isolated from Guttiferae and Ardisia species

Author:
Malina Jasamai; Juriyati Jalil; Ibrahim Jantan
Source:
Natural product research 2015 v.29 no.11 pp. 1055-1058
ISSN:
1478-6427
Subject:
Ardisia; Clusiaceae; antagonists; bioactive properties; computer software; mechanism of action; molecular models; platelet-activating factor; screening
Abstract:
... A handful of bioactive compounds from plants have been reported to possess platelet-activating factor (PAF) antagonist activity. However, their mode of action is not well understood. Selected bioactive compounds that exhibit PAF antagonist activity and synthetic PAF antagonists were subjected to docking simulations using the MOE 2007.09 software package. The docking study of PAF antagonists was ca ...
DOI:
10.1080/14786419.2014.971317

16. Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell-based assays

Author:
Sophie Kernéis; Lucy H. Swift; Cody W. Lewis; Céline Bruyère; Nassima Oumata; Pierre Colas; Sandrine Ruchaud; John Bain; Roy M. Golsteyn
Source:
Natural product research 2015 v.29 no.11 pp. 1026-1034
ISSN:
1478-6427
Subject:
Thermopsis; anticarcinogenic activity; beans; brain; buffaloes; cell adhesion; cell cycle; cell death; colon; cytotoxicity; ecological zones; flora; human cell lines; Canada
Abstract:
... Many plant species within the terrestrial ecological zones of Canada have not yet been investigated for anti-cancer activity. We examined the scientific literature describing the endemic flora from the prairie ecological zone and selected the species, Thermopsis rhombifolia , locally known as the buffalo bean, for investigation of its anti-cancer potential. We tested it in cell-based assays using ...
DOI:
10.1080/14786419.2014.979423

17. Neuroprotective effect of Brahmi, an ayurvedic drug against oxidative stress induced by methyl mercury toxicity in rat brain mitochondrial-enriched fractions

Author:
Dhanoop Manikoth Ayyathan; Rajasekaran Chandrasekaran; Kalaivani Thiagarajan
Source:
Natural product research 2015 v.29 no.11 pp. 1046-1051
ISSN:
1478-6427
Subject:
brain; catalase; drugs; enzyme activity; flavonoids; glutathione; high performance liquid chromatography; methylmercury compounds; neuroprotective effect; oxidative stress; phenols; rats; saponins; thiobarbituric acid-reactive substances; toxicity; viability
Abstract:
... The present study evaluates the neuroprotective effect of Brahmi against methyl mercury (MeHg) toxicity. The results demonstrated that MeHg-decreased mitochondrial viability in MTT assay and IC ₅₀ value was found to be 2.5 μg/mL. However, Brahmi at 250 μg/mL concentration effectively prevented mitochondrial damage caused by MeHg in MTT assay. Our results also demonstrated MeHg significantly inhibi ...
DOI:
10.1080/14786419.2014.968153

18. Supercritical CO2 extract and essential oil of aerial part of Ledum palustre L. – Chemical composition and anti-inflammatory activity

Author:
Sameh Baananou; Edita Bagdonaite; Bruno Marongiu; Alessandra Piras; Silvia Porcedda; Danilo Falconieri; Naceur A. Boughattas
Source:
Natural product research 2015 v.29 no.11 pp. 999-1005
ISSN:
1478-6427
Subject:
Rhododendron tomentosum; aerial parts; animals; anti-inflammatory activity; carbon dioxide; carrageenan; chemical composition; edema; essential oils; gas chromatography-mass spectrometry; ketoprofen; oils; sodium chloride; statistical analysis; supercritical fluid extraction
Abstract:
... The anti-inflammatory activity of two extracts from the aerial parts of Ledum palustre has been reported. The volatile oil was obtained by supercritical fluid extraction (SFE) and the essential oil by hydrodistillation (HD). The oils were analysed by gas chromatography–mass spectrometry to monitor their composition. Both extracts shared as main compound (41.0–43.4%) ledol (23.3–26.7%) and ascarido ...
DOI:
10.1080/14786419.2014.965167