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- Lin, Dingkun, et al. Show all 6 Authors
- Natural product research 2016 v.30 no.23 pp. 2716-2719
- adenosine; arachidonic acid; aspirin; computer software; platelet aggregation; prediction; stroke; water solubility
- ... New analogues of n-butylphthalide (NBP) bearing various lengths of alkyl and different substitution at the two-position of phthalide were designed and synthesised. Preliminary evaluation and prediction of ACD LogP software indicate that the derivatives display significant improvement in water solubility than NBP does. Further biological analysis showed that NBP analogues specifically inhibit plate ...