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- López, Marcela Dávila; Alm Rosenblad, Magnus; Samuelsson, Tore
- Nucleic acids research 2008 v.36 no.9 pp. 3001-3010
- chemical elements; RNA; Zygomycota; catalytic activity; covariance; Acanthamoeba castellanii; models; phylogeny; Trichinella spiralis; spliceosomes; Physarum polycephalum; Chytridiomycota; introns; fungi
- ... The RNA molecules of the spliceosome are critical for specificity and catalysis during splicing of eukaryotic pre-mRNA. In order to examine the evolution and phylogenetic distribution of these RNAs, we analyzed 149 eukaryotic genomes representing a broad range of phylogenetic groups. RNAs were predicted using high-sensitivity local alignment methods and profile HMMs in combination with covariance ...
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