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- Tang, Kuo-Hsiang; Niebuhr, Marc; Aulabaugh, Ann; Tsai, Ming-Daw
- Nucleic acids research 2008 v.36 no.3 pp. 849-860
- African swine fever virus; DNA; DNA-directed DNA polymerase; X-radiation; active sites; crystal structure; models; rats; ultracentrifugation
- ... We report small-angle X-ray scattering (SAXS) and sedimentation velocity (SV) studies on the enzyme-DNA complexes of rat DNA polymerase β (Pol β) and African swine fever virus DNA polymerase X (ASFV Pol X) with one-nucleotide gapped DNA. The results indicated formation of a 2 : 1 Pol β-DNA complex, whereas only 1 : 1 Pol X-DNA complex was observed. Three-dimensional structural models for the 2 : 1 ...
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