Jump to Main Content
- Draper, Will E.; Hayden, Eric J.; Lehman, Niles
- Nucleic acids research 2008 v.36 no.2 pp. 520-531
- Azoarcus; introns; magnesium chloride; mutants; mutation; oligonucleotides; ribozymes
- ... RNA oligomers of length 40-60 nt can self-assemble into covalent versions of the Azoarcus group I intron ribozyme. This process requires a series of recombination reactions in which the internal guide sequence of a nascent catalytic complex makes specific interactions with a complement triplet, CAU, in the oligomers. However, if the CAU were mutated, promiscuous self-assembly may be possible, less ...
- PubMed Central: