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- Lindhout, Beatrice I.; Fransz, Paul; Tessadori, Federico; Meckel, Tobias; Hooykaas, Paul J.J.; van der Zaal, Bert J.
- Nucleic acids research 2007 v.35 no.16 pp. e107
- chromocenters, etc ; Arabidopsis; DNA; binding sites; confocal microscopy; heterochromatin; image analysis; mice; microsatellite repeats; roots; tandem repeat sequences; transcription (genetics); transcription factors; zinc; zinc finger motif; Show all 15 Subjects
- ... Several techniques are available to study chromosomes or chromosomal domains in nuclei of chemically fixed or living cells. Current methods to detect DNA sequences in vivo are limited to trans interactions between a DNA sequence and a transcription factor from natural systems. Here, we expand live cell imaging tools using a novel approach based on zinc finger-DNA recognition codes. We constructed ...
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