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1. Assessing Validity of Self-Reported Dietary Intake within a Mediterranean Diet Cluster Randomized Controlled Trial among US Firefighters

Author:
Sotos-Prieto, Mercedes; Christophi, Costas; Black, Alicen; Furtado, Jeremy D; Song, Yiqing; Magiatis, Prokopios; Papakonstantinou, Aikaterini; Melliou, Eleni; Moffatt, Steven; Kales, Stefanos N.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Mediterranean diet; biomarkers; blood serum; compliance; computer software; data collection; fire fighters; fish consumption; food frequency questionnaires; interleukin-6; nutrient intake; nutritional intervention; oleic acid; olive oil; processed meat; randomized clinical trials; regression analysis; saturated fatty acids; t-test; tumor necrosis factor-alpha; urine; United States
Abstract:
... Collecting dietary intake data is associated with challenges due to the subjective nature of self–administered instruments. Biomarkers may objectively estimate the consumption of specific dietary items or help assess compliance in dietary intervention studies. Our aim was to use a panel of plasma and urine biomarkers to assess the validity of self-reported dietary intake using a modified Med ...
DOI:
10.3390/nu11092250

2. Dietary Acid Load: A Novel Nutritional Target in Overweight/Obese Children with Asthma?

Author:
Cunha, Pedro; Paciência, Inês; Cavaleiro Rufo, João; Castro Mendes, Francisca; Farraia, Mariana; Barros, Renata; Silva, Diana; Delgado, Luís; Padrão, Patrícia; Moreira, André; Moreira, Pedro
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
asthma; body mass index; childhood obesity; children; cough; diet recall; dyspnea; educational status; energy intake; enzymes; equations; females; inflammation; lung function; lungs; nutrients; odds ratio; pH; phenotype; physical activity
Abstract:
... Obesity has been repeatedly linked to asthma, and several potential mechanisms have been proposed in the etiologies of the obese-asthma phenotype. Considering that lungs play an important role in systemic pH and acid–base regulation, are a key organ in asthma development, and that nutritional inadequacy of several nutrients and high dietary acid load can affect airway inflammation and reacti ...
DOI:
10.3390/nu11092255

3. Differential Impact of Ad Libitum or Intermittent High-Fat Diets on Bingeing Ethanol-Mediated Behaviors

Author:
Del Olmo, Nuria; Blanco-Gandía, M. Carmen; Mateos-García, Ana; Del Rio, Danila; Miñarro, José; Ruiz-Gayo, Mariano; Rodríguez-Arias, Marta
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
adolescence; adolescents; alcohol drinking; animal models; anxiety; binging; cognition; ethanol; gene expression; gene expression regulation; genes; high fat diet; hippocampus; insulin; leptin; leptin receptors; memory; memory disorders; mice; motivation; prefrontal cortex; tranquilizers; white adipose tissue
Abstract:
... Background: Dietary factors have significant effects on the brain, modulating mood, anxiety, motivation and cognition. To date, no attention has been paid to the consequences that the combination of ethanol (EtOH) and a high-fat diet (HFD) have on learning and mood disorders during adolescence. The aim of the present work was to evaluate the biochemical and behavioral consequences of ethanol binge ...
DOI:
10.3390/nu11092253

4. Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption

Author:
Shang, Nan; Wu, Jianping
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
B-cell lymphoma; B-lymphocytes; antioxidants; apoptosis; bone resorption; death; egg albumen; ligands; macrophages; mice; mitogen-activated protein kinase; osteoclasts; osteoporosis; signal transduction; transcription factor NF-kappa B; transferrin
Abstract:
... Ovotransferrin, a member of the transferrin family, is the second main protein found in egg white. Ovotransferrin was reported to have antimicrobial, antioxidant, and immunomodulating activities. The aim of this work was to characterize the cellular and molecular functions of egg white ovotransferrin on osteoclasts differentiation and function. Osteoclasts were prepared from mouse macrophage RAW 2 ...
DOI:
10.3390/nu11092254

5. Expression of Renin-Angiotensin System Components in the Taste Organ of Mice

Author:
Shigemura, Noriatsu; Takai, Shingo; Hirose, Fumie; Yoshida, Ryusuke; Sanematsu, Keisuke; Ninomiya, Yuzo
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
angiotensin II; angiotensinogen; body fluids; epithelium; homeostasis; mice; palps; renin; renin-angiotensin system; sodium; sodium channels; sweetness; taste receptors; taste sensitivity
Abstract:
... The systemic renin-angiotensin system (RAS) is an important regulator of body fluid and sodium homeostasis. Angiotensin II (AngII) is a key active product of the RAS. We previously revealed that circulating AngII suppresses amiloride-sensitive salt taste responses and enhances the responses to sweet compounds via the AngII type 1 receptor (AT1) expressed in taste cells. However, the molecular mech ...
DOI:
10.3390/nu11092251

6. Face-to-Face and Digital Multidomain Lifestyle Interventions to Enhance Cognitive Reserve and Reduce Risk of Alzheimer’s Disease and Related Dementias: A Review of Completed and Prospective Studies

Author:
Bott, Nicholas T.; Hall, Aidan; Madero, Erica N.; Glenn, Jordan M.; Fuseya, Nami; Gills, Joshua L.; Gray, Michelle
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Alzheimer disease; Internet; cognition; cognitive disorders; databases; experimental design; lifestyle; prospective studies; risk; risk reduction
Abstract:
... Background: Currently, there is no pharmaceutical intervention to treat or delay pathological cognitive decline or Alzheimer’s disease and related dementias (ADRD). Multidomain lifestyle interventions are increasingly being studied as a non-pharmacological solution to enhance cognitive reserve, maintain cognition, and reduce the risk of or delay ADRD. Review of completed and prospective face ...
DOI:
10.3390/nu11092258

7. Immunomodulatory Effects of Fruiting Body Extract and Solid-State-Cultivated Mycelia of <i>Taiwanofungus camphoratus</i>

Author:
Lin, Liang-Hung; Chi, Ching-Hsin; Zhang, Xiao-Han; Chen, Ying-Ju; Wang, Ming-Fu
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Taiwanofungus camphoratus; blood serum; females; foods; fruiting bodies; healthy diet; immunoglobulin E; immunomodulators; interferon-gamma; interleukin-2; interleukin-4; interleukin-5; macrophages; medicinal fungi; mice; mycelium; natural killer cells; oral administration; ovalbumin; tumor necrosis factor-alpha; Taiwan
Abstract:
... Taiwanofungus camphoratus is a rare and valuable medicinal mushroom indigenous to Taiwan. It has traditionally been used to promote good health. This study aimed to explore the immunomodulatory effects of “Leader Deluxe Taiwanofungus camphoratus capsule” (LDAC). LDAC is a healthy food product composed of fruiting body extract and solid-state-cultivated mycelia of T. camphoratus. Two co ...
DOI:
10.3390/nu11092256

8. Maternal Dietary Protein Intake Influences Milk and Offspring Gut Microbial Diversity in a Rat (<em>Rattus norvegicus</em>) Model

Author:
Warren, Matthew F.; Hallowell, Haley A.; Higgins, Keah V.; Liles, Mark R.; Hood, Wendy R.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Lactobacillus; Rattus norvegicus; animal models; bacteria; cecum; dietary protein; females; genes; health promotion; high protein diet; inoculum; intestinal microorganisms; lactation; maternal effect; maternal nutrition; microbial communities; microbiome; milk; neonates; progeny; protein content; protein intake; pups; rats; ribosomal RNA
Abstract:
... Historically, investigators have assumed microorganisms identified in mother’s milk to be contaminants, but recent data suggest that milk microbiota may contribute to beneficial maternal effects. Microorganisms that colonize the gastrointestinal tracts of newborn mammals are derived, at least in part, from the maternal microbial population. Milk-derived microbiota is an important source of this mi ...
DOI:
10.3390/nu11092257

9. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine-Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult <i>Pah-Enu2</i> Mice

Author:
van Vliet, Danique; van der Goot, Els; van Ginkel, Wiggert G.; van Faassen, Martijn H. J. R.; de Blaauw, Pim; Kema, Ido P.; Martinez, Aurora; Heiner-Fokkema, M. Rebecca; van der Zee, Eddy A.; van Spronsen, Francjan J.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
adults; amino acid composition; blood plasma; brain; diet; dietary restriction; guidelines; mice; monoamines; neurotransmitters; norepinephrine; patients; phenylalanine; phenylketonuria; serotonin
Abstract:
... Many phenylketonuria (PKU) patients cannot adhere to the severe dietary restrictions as advised by the European PKU guidelines, which can be accompanied by aggravated neuropsychological impairments that, at least in part, have been attributed to brain monoaminergic neurotransmitter deficiencies. Supplementation of large neutral amino acids (LNAA) to an unrestricted diet has previously been shown t ...
DOI:
10.3390/nu11092252

10. The Effect of 12 Weeks of β-Hydroxy-β-Methyl-Butyrate Supplementation after Liver Transplantation: A Pilot Randomized Controlled Study

Author:
Lattanzi, Barbara; Giusto, Michela; Albanese, Carlina; Mennini, Gianluca; D’Ambrosio, Daria; Farcomeni, Alessio; Ginanni Corradini, Stefano; Rossi, Massimo; Merli, Manuela
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
adverse effects; anthropometric measurements; body composition; diet; dual-energy X-ray absorptiometry; liver transplant; males; patients; physical activity; sarcopenia; skeletal muscle
Abstract:
... Sarcopenia is a frequent complication in liver transplant (LT) recipients. β-hydroxy-β-methyl-butyrate (HMB) has the potential to increase muscle-performance and tropism. Our study aims at evaluating the effect on muscle mass and functioning, and the safety of 12 weeks of HMB supplementation in patients after LT. This is a pilot, randomized study. Male patients undergoing LT were randoml ...
DOI:
10.3390/nu11092259

11. A Lowly Digestible-Starch Diet after Weaning Enhances Exogenous Glucose Oxidation Rate in Female, but Not in Male, Mice

Author:
Fernández-Calleja, José M. S.; Bouwman, Lianne M. S.; Swarts, Hans J. M.; Billecke, Nils; Oosting, Annemarie; Keijer, Jaap; van Schothorst, Evert M.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
amylases; body composition; body weight; calorimetry; carbon; diet; digestibility; digestible energy; energy expenditure; energy intake; enzyme activity; females; glucose; hydrogen production; males; metabolism; mice; oxidation; stable isotopes; starch; weaning
Abstract:
... Starches of low digestibility are associated with improved glucose metabolism. We hypothesise that a lowly digestible-starch diet (LDD) versus a highly digestible-starch diet (HDD) improves the capacity to oxidise starch, and that this is sex-dependent. Mice were fed a LDD or a HDD for 3 weeks directly after weaning. Body weight (BW), body composition (BC), and digestible energy intake (dEI) were ...
DOI:
10.3390/nu11092242

12. Environmental Sustainability Perspectives of the Nordic Diet

Author:
Meltzer, Helle Margrete; Brantsæter, Anne Lise; Trolle, Ellen; Eneroth, Hanna; Fogelholm, Mikael; Ydersbond, Trond Arild; Birgisdottir, Bryndis Eva
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Dietary Guidelines; animal-based foods; environmental sustainability; food intake; foodways; guidelines; health promotion; humans; issues and policy; Scandinavia
Abstract:
... “The Nordic diet” is an umbrella term that encompasses any interpretation that combines Food-Based Dietary Guidelines (FBDGs) with local Nordic foods. The five Nordic countries have collaborated on Nordic Nutrition Recommendations for forty years, including FBDGs, so their national guidelines are similar. The countries also share similar public health issues, including widespread nonco ...
DOI:
10.3390/nu11092248

13. Factors Associated with Sarcopenia and 7-Year Mortality in Very Old Patients with Hip Fracture Admitted to Rehabilitation Units: A Pragmatic Study

Author:
Malafarina, Vincenzo; Malafarina, Concetta; Biain Ugarte, Arantzazu; Martinez, J. Alfredo; Abete Goñi, Itziar; Zulet, M. Angeles
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
elderly; hip fractures; hospitals; malnutrition; mortality; observational studies; patients; regression analysis; risk factors; sarcopenia; skeletal muscle; women
Abstract:
... Background: Admitted bedridden older patients are at risk of the development of sarcopenia during hospital stay (incident sarcopenia). The objective of this study was to assess the factors associated with sarcopenia (incident and chronic) and its impact on mortality in older people with hip fracture. Methods: A multicenter, pragmatic, prospective observational study was designed. Older subjects wi ...
DOI:
10.3390/nu11092243

14. Generation of the Antioxidant Hydroxytyrosol from Tyrosol Present in Beer and Red Wine in a Randomized Clinical Trial

Author:
Soldevila-Domenech, Natalia; Boronat, Anna; Mateus, Julian; Diaz-Pellicer, Patricia; Matilla, Iris; Pérez-Otero, Marta; Aldea-Perona, Ana; de la Torre, Rafael
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
antioxidants; beers; biotransformation; dose response; enzymes; gender differences; genotyping; phenol; randomized clinical trials; red wines
Abstract:
... Beer and wine contains the simple phenol tyrosol (TYR) which is endogenously converted into hydroxytyrosol (HT), one of the strongest dietary antioxidants, by CYP2A6 and CYP2D6 polymorphic enzymes. We investigated in humans the rate of this bioconversion after beer and red wine (RW) intake. In a single blind, randomized, crossover, controlled clinical trial (n = 20 healthy subjects), we evaluated ...
DOI:
10.3390/nu11092241

15. <i>N</i>-Eicosapentaenoyl Dopamine, A Conjugate of Dopamine and Eicosapentaenoic Acid (EPA), Exerts Anti-inflammatory Properties in Mouse and Human Macrophages

Author:
Augimeri, Giuseppina; Plastina, Pierluigi; Gionfriddo, Giulia; Rovito, Daniela; Giordano, Cinzia; Fazio, Alessia; Barone, Ines; Catalano, Stefania; Andò, Sebastiano; Bonofiglio, Daniela; Meijerink, Jocelijn; Witkamp, Renger
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
amides; amino acids; anti-inflammatory activity; apoptosis; autophagy; cannabinoids; cell lines; chemokine CCL2; chemokine CCL20; docosahexaenoic acid; dopamine; eicosapentaenoic acid; humans; immunomodulators; interleukin-1beta; interleukin-6; lipopolysaccharides; macrophages; metabolites; mice; neoplasms; nitric oxide; omega-3 fatty acids; prostaglandin synthase; risk; transcription (genetics)
Abstract:
... A large body of evidence suggests that dietary n-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), contribute to a reduced inflammatory tone thereby lowering the risk for several chronic and degenerative diseases. Different mechanisms have been proposed to explain these anti-inflammatory effects, including those involving endocannabinoids ...
DOI:
10.3390/nu11092247

16. Iron Fortification and Bioavailability of Chickpea (<i>Cicer arietinum</i> L.) Seeds and Flour

Author:
Jahan, Tamanna A.; Vandenberg, Albert; Glahn, Raymond P.; Tyler, Robert T.; Reaney, Martin J. T.; Tar’an, Bunyamin
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Cicer arietinum; EDTA (chelating agent); bioavailability; chickpeas; consumer acceptance; diet-related diseases; drying; ferritin; ferrous sulfate; flour; hedonic scales; iron; nutrient deficiencies; seeds; sensory evaluation; sodium; soups; spraying
Abstract:
... Iron (Fe) deficiency is one of the most common nutritional disorders, and is mainly due to insufficient intake of bioavailable Fe. Chickpea (Cicer arietinum L.) was examined as a potential vehicle for Fe fortification. Fortificants (FeSO4·7H2O (ferrous sulfate hepta-hydrate), FeSO4·H2O (ferrous sulfate mono-hydrate) and NaFeEDTA (ethylenedi ...
DOI:
10.3390/nu11092240

17. Plant Bioactives and the Prevention of Prostate Cancer: Evidence from Human Studies

Author:
Livingstone, Tracey L.; Beasy, Gemma; Mills, Robert D.; Plumb, Jenny; Needs, Paul W.; Mithen, Richard; Traka, Maria H.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
Brassicaceae; bioactive compounds; carotenoids; clinical trials; epidemiological studies; etiology; food groups; garlic; green tea; humans; males; men; nutrition; pathogenesis; phytochemicals; plant-based foods; polyphenols; pomegranates; prostatic neoplasms; risk reduction; tomatoes; United Kingdom
Abstract:
... Prostate cancer has become the most common form of non-cutaneous (internal) malignancy in men, accounting for 26% of all new male visceral cancer cases in the UK. The aetiology and pathogenesis of prostate cancer are not understood, but given the age-adjusted geographical variations in prostate cancer incidence quoted in epidemiological studies, there is increasing interest in nutrition as a relev ...
DOI:
10.3390/nu11092245

18. Serum ‘Vitamin-Mineral’ Profiles: Associations with Postmenopausal Breast Cancer Risk Including Dietary Patterns and Supplementation. A Case-Control Study

Author:
Krusinska, Beata; Wadolowska, Lidia; Biernacki, Maciej; Slowinska, Malgorzata Anna; Drozdowski, Marek
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
biomarkers; blood serum; body mass index; breast neoplasms; calcium; case-control studies; confidence interval; contraceptives; etiology; fasting; females; folic acid; hormone replacement therapy; iron; magnesium; menarche; minerals; monitoring; nutrition risk assessment; odds ratio; physical activity; postmenopause; pregnancy; principal component analysis; regression analysis; smoking (habit); socioeconomic status; vitamin B12; vitamin D; women; Poland
Abstract:
... Breast cancer is the most prevalent cancer in females worldwide. Studies evaluating the blood vitamins and minerals status in the breast cancer etiology are limited, and the results are inconclusive. This study analyzed the association between serum vitamin-mineral profiles (V-MPs) and breast cancer (BC) risk with including dietary patterns (DPs) and the use of supplements. This case-control study ...
DOI:
10.3390/nu11092244

19. The Clinical Importance of 21-Day Combined Parenteral and Enteral Nutrition in Active Inflammatory Bowel Disease Patients

Author:
Mańkowska-Wierzbicka, Dorota; Karczewski, Jacek; Swora-Cwynar, Ewelina; Dobrowolska, Agnieszka; Stelmach-Mardas, Marta
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
adiponectin; blood serum; colitis; creatinine; energy; enteral feeding; guidelines; hospitals; leptin; lipid composition; parenteral feeding; patients; thyrotropin; tumor necrosis factor-alpha; vitamin B12
Abstract:
... The aim of the study was to show the clinical magnitude of short-term feeding: enteral nutrition (EN) combined with parenteral nutrition (PN) in active Crohn’s disease and ulcerative colitis patients. Among 122 eligible inflammatory bowel disease (IBD) patients, 65 met the inclusion criteria. Combined EN and PN was administered for 21 days, wherein over the first 3–5 days of treatment, ...
DOI:
10.3390/nu11092246

20. The Impact of Nutrition Education Intervention with and Without a Mobile Phone Application on Nutrition Knowledge Among Young Endurance Athletes

Author:
Heikkilä, Maria; Lehtovirta, Mikko; Autio, Ossi; Fogelholm, Mikael; Valve, Raisa
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
athletes; carbohydrates; educational planning; energy intake; food intake; food records; learning; mobile telephones; nutrition education; nutrition knowledge; questionnaires
Abstract:
... Athletes often have significant gaps in their nutrition knowledge. Thus, the aim of this study was to investigate whether young Finnish endurance athletes’ nutrition knowledge and dietary intake can be improved through an education intervention with or without a mobile food application. Seventy-nine endurance athletes, 18.0 years (SD: 1.4), participated in this randomized, controlled interve ...
DOI:
10.3390/nu11092249