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51. Faecal Short Chain Fatty Acids Profile is Changed in Polish Depressive Women

Author:
Skonieczna-Żydecka, Karolina; Grochans, Elżbieta; Maciejewska, Dominika; Szkup, Małgorzata; Schneider-Matyka, Daria; Jurczak, Anna; Łoniewski, Igor; Kaczmarczyk, Mariusz; Marlicz, Wojciech; Czerwińska-Rogowska, Maja; Pełka-Wysiecka, Justyna; Dec, Karolina; Stachowska, Ewa
Source:
Nutrients 2018 v.10 no.12
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; acetates; acetic acid; butyric acid; byproducts; cognition; drug therapy; drugs; fatty acid composition; fermentation; food frequency questionnaires; gas chromatography; hexanoic acid; inventories; isobutyric acid; mental depression; microorganisms; phenotype; polysaccharides; propionic acid; thyroid diseases; valeric acid; women;     Show all 23 Subjects
Abstract:
... Short chain fatty acids (SCFAs) being produced during fermentation of non-digestible polysaccharides are regulatory compounds with the potential to influence inflammatory, as well as emotional state and cognition through the gut–brain axis. We analyzed the association between stool concentration of SCFAs (acetic acid (C 2:0), propionic acid (C 3:0), isobutyric acid (C 4:0 i), butyric acid (C ...
DOI:
10.3390/nu10121939

52. Dietary Composition and Cardiovascular Risk: A Mediator or a Bystander?

Author:
Korakas, Emmanouil; Dimitriadis, George; Raptis, Athanasios; Lambadiari, Vaia
Source:
Nutrients 2018 v.10 no.12
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Mediterranean diet; atherosclerosis; cardioprotective effect; carotenoids; diabetes; eating habits; glucose; high fat diet; homeostasis; intestinal microorganisms; obesity; omega-3 fatty acids; oxidative stress; pathogenesis; polyphenols; polyunsaturated fatty acids; risk factors; vitamins;     Show all 19 Subjects
Abstract:
... The role of nutrition in the pathogenesis of cardiovascular disease has long been debated. The established notion of the deleterious effects of fat is recently under question, with numerous studies demonstrating the benefits of low-carbohydrate, high-fat diets in terms of obesity, diabetes, dyslipidemia, and metabolic derangement. Monounsaturated and polyunsaturated fatty acids, especially n-3 PUF ...
DOI:
10.3390/nu10121912

53. Role of Synbiotics Containing <span style="font-variant: small-caps">d</span>-Allulose in the Alteration of Body Fat and Hepatic Lipids in Diet-Induced Obese Mice

Author:
Choi, Bo-Ra; Kwon, Eun-Young; Kim, Hye-Jin; Choi, Myung-Sook
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Lactobacillus sakei; Leuconostoc kimchii; adiponectin; adiposity; animal disease models; fatty acids; food industry; high fat diet; interleukin-1beta; interleukin-6; leptin; lipid metabolism; mice; obesity; prebiotics; probiotics; psicose; resistin; synergism; triacylglycerols; white adipose tissue;     Show all 22 Subjects
Abstract:
... The effects of allulose and two probiotic species on diet-induced obese (DIO) mice were investigated. Lactobacillus sakei LS03 (109 cfu/day) and Leuconostoc kimchii GJ2 (109 cfu/day) were used as probiotics, and allulose (AL) as a prebiotic. The synergistic effect of prebiotics and probiotics in improving obesity was evaluated. Orally fed Lactobacillus sakei LS03 (LS) or Leuconostoc kimchii GJ2 (G ...
DOI:
10.3390/nu10111797

54. ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners

Author:
Iizuka, Katsumi; Takao, Ken; Kato, Takehiro; Horikawa, Yukio; Takeda, Jun
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; 3-hydroxybutyric acid; Adenoviridae; beta oxidation; carbohydrates; dissociation; fatty liver; fibroblast growth factors; free fatty acids; gene expression; green fluorescent protein; lipid composition; lipogenesis; lipolysis; liver; messenger RNA; mice; protein content; triacylglycerols; very low density lipoprotein; white adipose tissue;     Show all 21 Subjects
Abstract:
... Carbohydrate response element-binding protein (ChREBP) has an important role in the carbohydrate-mediated regulation of hepatic de novo lipogenesis, but the mechanism for how it regulates plasma triacylglycerol (TAG) levels has not been established. This study aimed to clarify the role of ChREBP in regulation of plasma TAG levels. We analyzed the metabolic changes in mice infected with an adenovir ...
DOI:
10.3390/nu10111699

55. Association between Cardiac Remodeling and Metabolic Alteration in an Experimental Model of Obesity Induced by Western Diet

Author:
Ferron, Artur Junio Togneri; Francisqueti, Fabiane Valentini; Minatel, Igor Otávio; Silva, Carol Cristina Vágula de Almeida; Bazan, Silméia Garcia Zanati; Kitawara, Koody André Hassemi; Garcia, Jéssica Leite; Corrêa, Camila Renata; Moreto, Fernando; Ferreira, Ana Lucia A.
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Western diets; ad libitum feeding; blood glucose; cholesterol; echocardiography; energy intake; feed conversion; glucose; high density lipoprotein; high fat diet; hypertension; insulin; laboratory animals; lipid composition; models; obesity; rats; sucrose; systolic blood pressure; triacylglycerols; uric acid; weight gain;     Show all 23 Subjects
Abstract:
... The high consumption of fat and sugar contributes to the development of obesity and co-morbidities, such as dyslipidemia, hypertension, and cardiovascular disease. The aim of this study was to evaluate the association between dyslipidemia and cardiac dysfunction induced by western diet consumption. Wistar rats were randomly divided into two experimental groups and fed ad libitum for 20 weeks with ...
DOI:
10.3390/nu10111675

56. Effects of Metformin Combined with Lactoferrin on Lipid Accumulation and Metabolism in Mice Fed with High-Fat Diet

Author:
Min, Qing-Qing; Qin, Li-Qiang; Sun, Zhen-Zhen; Zuo, Wen-Ting; Zhao, Lin; Xu, Jia-Ying
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adipocytes; biosynthesis; blood serum; body mass index; cholesterol; drinking water; energy; enzymes; glucose; high fat diet; histology; homeostasis; lactoferrin; lipid composition; lipid metabolism; liver; metformin; mice; obesity; protein synthesis; visceral fat; weight control;     Show all 23 Subjects
Abstract:
... Metformin (Met) and lactoferrin (Lf) both exhibit beneficial effects on body weight management and lipid accumulation. However, the synergistical action of Met and Lf remains unclear. In this study, 64 mice were divided into five groups, namely, the control group, high-fat diet (HFD group), HFD with Met (Met group), Lf (Lf group), and a combination of Met and Lf (Met + Lf group). Met (200 mg/kg bo ...
DOI:
10.3390/nu10111628

57. Achacha (<em>Garcinia humilis</em>) Rind Improves Cardiovascular Function in Rats with Diet-Induced Metabolic Syndrome

Author:
John, Oliver D.; Wanyonyi, Stephen; Mouatt, Peter; Panchal, Sunil K.; Brown, Lindsay
Source:
Nutrients 2018 v.10 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Garcinia; animal models; body composition; byproducts; cardioprotective effect; citric acid; collagen; corn starch; fatty liver; fruits; glucose tolerance; high fat diet; hypertension; laboratory animals; males; metabolic syndrome; obesity; phytochemicals; procyanidins; pulp; rats; systolic blood pressure; Australia; Bolivia; Brazil; Peru;     Show all 27 Subjects
Abstract:
... Garcinia humilis is a fruit known as achachairú. It is native to South American countries such as Bolivia, Peru, and Brazil, but it is also cultivated as achacha in northern Australia. The aim of this study was to determine the phytochemicals in achacha rind and pulp and to investigate these components as potential treatments for the symptoms of metabolic syndrome. Both rind and pulp contain procy ...
DOI:
10.3390/nu10101425

58. NADH Dehydrogenase Subunit-2 237 Leu/Met Polymorphism Influences the Association of Coffee Consumption with Serum Chloride Levels in Male Japanese Health Checkup Examinees: An Exploratory Cross-Sectional Analysis

Author:
Kokaze, Akatsuki; Ishikawa, Mamoru; Matsunaga, Naomi; Karita, Kanae; Yoshida, Masao; Ochiai, Hirotaka; Shirasawa, Takako; Yoshimoto, Takahiko; Minoura, Akira; Oikawa, Kosuke; Satoh, Masao; Hoshino, Hiromi; Takashima, Yutaka
Source:
Nutrients 2018 v.10 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Japanese people; NAD (coenzyme); NADH dehydrogenase; alcohol drinking; blood serum; body mass index; confidence interval; cross-sectional studies; drug therapy; electrolytes; genotype; genotyping; glucose tolerance; green tea; hospitals; hypertension; leucine; males; men; methionine; mortality; odds ratio; standard deviation;     Show all 24 Subjects
Abstract:
... Background: Nicotinamide adenine dinucleotide (NADH) dehydrogenase subunit-2 237 leucine/methionine (ND2-237 Leu/Met) polymorphism has been shown to modify the association of coffee consumption with the risk of hypertension, dyslipidemia, and abnormal glucose tolerance, and low serum chloride levels have been shown to be associated with all-cause and cardiovascular disease mortality. Therefore, th ...
DOI:
10.3390/nu10101344

59. Moderate Beer Intake and Cardiovascular Health in Overweight Individuals

Author:
Padro, Teresa; Muñoz-García, Natàlia; Vilahur, Gemma; Chagas, Patricia; Deyà, Alba; Antonijoan, Rosa Maria; Badimon, Lina
Source:
Nutrients 2018 v.10 no.9
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; alcohol drinking; antioxidant activity; beers; biomarkers; blood serum; body mass index; cholesterol; cross-over studies; high density lipoprotein; hypertension; kidneys; liver; macrophages; men; metabolic syndrome; noninsulin-dependent diabetes mellitus; overweight; prospective studies; renal function; risk factors; women;     Show all 22 Subjects
Abstract:
... Consistent epidemiological evidence indicates that low-to-moderate alcohol consumption is inversely associated with cardiovascular event presentation, while high levels of alcohol intake are associated to increased cardiovascular risk. Little is known on the effects of moderate beer intake in the metabolic syndrome. The aim of this study is to investigate the effects of moderate and regular daily ...
DOI:
10.3390/nu10091237

60. Red Blood Cell Aggregation-Associated Dietary Pattern Predicts Hyperlipidemia and Metabolic Syndrome

Author:
Lin, Pei; Chang, Chun-Chao; Yuan, Kuo-Ching; Yeh, Hsing-Jung; Fang, Sheng-Uei; Cheng, Tiong; Teng, Kai-Tse; Chao, Kuo-Ching; Tang, Jui-Hsiang; Kao, Wei-Yu; Lin, Pao-Ying; Liu, Ju-Shian; Chang, Jung-Su
Source:
Nutrients 2018 v.10 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adults; blood serum; body mass index; dairy products; eating habits; erythrocytes; food frequency questionnaires; food groups; fried foods; hepcidin; iron; metabolic syndrome; noodles; nutrition risk assessment; raw foods; regression analysis; rice; seafoods; transferrin; vegetables;     Show all 21 Subjects
Abstract:
... Red blood cell (RBC) aggregation and iron status are interrelated and strongly influenced by dietary factors, and their alterations pose a great risk of dyslipidemia and metabolic syndrome (MetS). Currently, RBC aggregation-related dietary patterns remain unclear. This study investigated the dietary patterns that were associated with RBC aggregation and their predictive effects on hyperlipidemia a ...
DOI:
10.3390/nu10081127

61. A Review on the Protective Effects of Honey against Metabolic Syndrome

Author:
Ramli, Nur Zuliani; Chin, Kok-Yong; Zarkasi, Khairul Anwar; Ahmad, Fairus
Source:
Nutrients 2018 v.10 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; antioxidant activity; atherogenesis; blood glucose; cholesterol; diabetes mellitus; glycemic index; high density lipoprotein; honey; hypertension; insulin resistance; lipid metabolism; low density lipoprotein; metabolic syndrome; obesity; oxidative stress; pancreas; protective effect; risk reduction; therapeutics; triacylglycerols; weight gain;     Show all 22 Subjects
Abstract:
... Metabolic syndrome (MetS) is a cluster of diseases comprising of obesity, diabetes mellitus, dyslipidemia, and hypertension. There are numerous pre-clinical as well as human studies reporting the protective effects of honey against MetS. Honey is a nutritional food low in glycemic index. Honey intake reduces blood sugar levels and prevents excessive weight gain. It also improves lipid metabolism b ...
DOI:
10.3390/nu10081009

62. French Recommendations for Sugar Intake in Adults: A Novel Approach Chosen by ANSES

Author:
Tappy, Luc; Morio, Béatrice; Azzout-Marniche, Dalila; Champ, Martine; Gerber, Mariette; Houdart, Sabine; Mas, Emmanuel; Rizkalla, Salwa; Slama, Gérard; Mariotti, François; Margaritis, Irène
Source:
Nutrients 2018 v.10 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adults; blood; body weight changes; cardiovascular diseases; cohort studies; diabetes; energy intake; experts; fatty liver; fructose; honey; hyperuricemia; insulin resistance; nutrition risk assessment; obesity; randomized clinical trials; sucrose; syrups; systematic review; triacylglycerols; uric acid;     Show all 22 Subjects
Abstract:
... This article presents a systematic review of the scientific evidence linking sugar consumption and health in the adult population performed by a group of experts, mandated by the French Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement, et du travail (ANSES). A literature search was performed by crossing search terms for overweight/obesity, diabetes/insulin resistance, d ...
DOI:
10.3390/nu10080989

63. Luteolin-Enriched Artichoke Leaf Extract Alleviates the Metabolic Syndrome in Mice with High-Fat Diet-Induced Obesity

Author:
Kwon, Eun-Young; Kim, So Young; Choi, Myung-Sook
Source:
Nutrients 2018 v.10 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adiposity; artichokes; beta oxidation; enzymes; excretion; fatty liver; gastric inhibitory polypeptide; high fat diet; inflammation; insulin resistance; interleukin-1beta; interleukin-6; leaf extracts; leaves; lipogenesis; luteolin; metabolic syndrome; mice; obesity; plasminogen activator inhibitors; sterols;     Show all 22 Subjects
Abstract:
... This current study aimed to elucidate the effects and possible underlying mechanisms of long-term supplementation with dietary luteolin (LU)-enriched artichoke leaf (AR) in high-fat diet (HFD)-induced obesity and its complications (e.g., dyslipidemia, insulin resistance, and non-alcoholic fatty liver disease) in C57BL/6N mice. The mice were fed a normal diet, an HFD, or an HFD plus AR or LU for 16 ...
DOI:
10.3390/nu10080979

64. The Association of Dietary Cholesterol and Fatty Acids with Dyslipidemia in Chinese Metropolitan Men and Women

Author:
Zhu, Zhenni; Wu, Fan; Lu, Ye; Wang, Zhengyuan; Zang, Jiajie; Yu, Huiting; Guo, Changyi; Jia, Xiaodong; Shen, Xianbiao; Ding, Gangqiang
Source:
Nutrients 2018 v.10 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; National Cholesterol Education Program; adults; blood lipids; blood serum; cholesterol; dietary fat; fatty acids; females; food intake; health surveys; males; men; nutrition risk assessment; women; China; United States;     Show all 17 Subjects
Abstract:
... Background: The associations between dietary cholesterol and fatty acids and serum lipids are controversial. This study is to examine the association of dietary cholesterol and fatty acids with serum lipids and dyslipidemia in Chinese metropolitan male and female adults. Methods: 3850 participants in the Shanghai Diet and Health Survey were investigated during the period 2012–2013. Informati ...
DOI:
10.3390/nu10080961

65. High-Glucose or -Fructose Diet Cause Changes of the Gut Microbiota and Metabolic Disorders in Mice without Body Weight Change

Author:
Do, Moon Ho; Lee, Eunjung; Oh, Mi-Jin; Kim, Yoonsook; Park, Ho-Young
Source:
Nutrients 2018 v.10 no.6
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Bacteroidetes; Proteobacteria; Western blotting; blood glucose; diet; endotoxemia; endotoxins; fatty liver; fructose; glucose; histology; inflammation; insulin tolerance test; intestinal microorganisms; intestines; lipids; mice; obesity; permeability; proteins; ribosomal RNA; tight junctions;     Show all 23 Subjects
Abstract:
... High fat diet-induced changes in gut microbiota have been linked to intestinal permeability and metabolic endotoxemia, which is related to metabolic disorders. However, the influence of a high-glucose (HGD) or high-fructose (HFrD) diet on gut microbiota is largely unknown. We performed changes of gut microbiota in HGD- or HFrD-fed C57BL/6J mice by 16S rRNA analysis. Gut microbiota-derived endotoxi ...
DOI:
10.3390/nu10060761

66. Ferulic Acid Supplementation Improves Lipid Profiles, Oxidative Stress, and Inflammatory Status in Hyperlipidemic Subjects: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Author:
Bumrungpert, Akkarach; Lilitchan, Supathra; Tuntipopipat, Siriporn; Tirawanchai, Nednapis; Komindr, Surat
Source:
Nutrients 2018 v.10 no.6
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; anti-inflammatory activity; biomarkers; cardiovascular diseases; cholesterol; ferulic acid; inflammation; lipid composition; oxidation; oxidative stress; placebos; randomized clinical trials; risk factors; small cereal grains; triacylglycerols; tumor necrosis factor-alpha; vegetables;     Show all 17 Subjects
Abstract:
... Ferulic acid is the most abundant phenolic compound found in vegetables and cereal grains. In vitro and animal studies have shown ferulic acid has anti-hyperlipidemic, anti-oxidative, and anti-inflammatory effects. The objective of this study is to investigate the effects of ferulic acid supplementation on lipid profiles, oxidative stress, and inflammatory status in hyperlipidemia. The study desig ...
DOI:
10.3390/nu10060713

67. ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion

Author:
Niwa, Hiroyuki; Iizuka, Katsumi; Kato, Takehiro; Wu, Wudelehu; Tsuchida, Hiromi; Takao, Ken; Horikawa, Yukio; Takeda, Jun
Source:
Nutrients 2018 v.10 no.3
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Adenoviridae; binding proteins; carbohydrates; fatty liver; gene overexpression; genes; hepatocytes; liver; messenger RNA; mice; pathogenesis; protein content; pyruvate kinase; rats; secretion; transcription (genetics); triacylglycerols; very low density lipoprotein;     Show all 19 Subjects
Abstract:
... The regulation of hepatic very-low-density lipoprotein (VLDL) secretion plays an important role in the pathogenesis of dyslipidemia and fatty liver diseases. VLDL is controlled by hepatic microsomal triglyceride transfer protein (MTTP). Mttp is regulated by carbohydrate response element binding protein (ChREBP) and small heterodimer partner (SHP). However, it is unclear whether both coordinately r ...
DOI:
10.3390/nu10030321

68. Chronic Fructose Ingestion as a Major Health Concern: Is a Sedentary Lifestyle Making It Worse? A Review

Author:
Bidwell, Amy J.
Source:
Nutrients 2017 v.9 no.6
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adiposity; animal models; diabetes; diet; energy balance; exercise; fructose; glucose; glucose tolerance; high fat foods; hypertension; insulin resistance; lipids; metabolic syndrome; obesity; risk factors; sedentary lifestyle;     Show all 18 Subjects
Abstract:
... Obesity contributes to metabolic abnormalities such as insulin resistance, dyslipidemia, hypertension, and glucose intolerance, all of which are risk factors associated with metabolic syndrome. The growing prevelance of metabolic syndrome seems to be an end result of our current lifestyle which promotes high caloric, high-fat foods and minimal physical activity, resulting in a state of positive en ...
DOI:
10.3390/nu9060549

69. Bioactive Compounds and Their Neuroprotective Effects in Diabetic Complications

Author:
Oh, Yoon Sin
Source:
Nutrients 2016 v.8 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; bioactive compounds; clinical trials; diabetic neuropathy; flavonoids; hyperglycemia; insulin; mechanism of action; morbidity; mortality; neuroprotective effect; patients; therapeutics; vitamins;     Show all 14 Subjects
Abstract:
... Hyperglycemia, hyperlipidemia and impaired insulin signaling during the development of diabetes can cause diabetic complications, such as diabetic neuropathy, resulting in significant morbidity and mortality. Although various therapeutics are available for the treatment of diabetic neuropathy, no absolute cure exists, and additional research is necessary to comprehensively understand the underlyin ...
DOI:
10.3390/nu8080472

70. Gut Microbiota and Endothelial Dysfunction Markers in Obese Mexican Children and Adolescents

Author:
Nirmalkar, Khemlal; Murugesan, Selvasankar; Pizano-Zárate, María Luisa; Villalobos-Flores, Loan Edel; García-González, Cristina; Morales-Hernández, Rosa María; Nuñez-Hernández, Jorge Arturo; Hernández-Quiroz, Fernando; Romero-Figueroa, María del Socorro; Hernández-Guerrero, César; Hoyo-Vadillo, Carlos; García-Mena, Jaime
Source:
Nutrients 2018 v.10 no.12
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Bacteroides; C-reactive protein; Collinsella; Lactobacillus; Mexicans; Prevotella; Ruminococcus; Veillonellaceae; adiponectin; adolescents; bioactive compounds; blood sampling; childhood obesity; children; cholesterol; digestive system; high-throughput nucleotide sequencing; homeostasis; inflammation; insulin; insulin resistance; intercellular adhesion molecule-1; intestinal microorganisms; leptin; metabolic syndrome; models; multivariate analysis; ribosomal DNA; triacylglycerols; vascular cell adhesion molecules;     Show all 31 Subjects
Abstract:
... Obesity is a metabolic disease characterized by low-grade inflammation and accompanied by dyslipidemia and up-regulation of other bioactive molecules, creating a predisposition to endothelial dysfunction and metabolic syndrome. We studied the association between gut microbiota diversity and endothelial dysfunction (EDF) markers in obese Mexican children and adolescents. We examined clinical data i ...
DOI:
10.3390/nu10122009

71. Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets

Author:
Santos-López, Jorge Arturo; Garcimartín, Alba; Bastida, Sara; Bautista-Ávila, Mirandeli; González-Muñoz, María José; Benedí, Juana; Sánchez-Muniz, Francisco José
Source:
Nutrients 2018 v.10 no.12
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adipose tissue; alpha-linolenic acid; antioxidants; blood lipids; cholesterol; experimental diets; feed intake; free fatty acids; freeze drying; functional foods; genes; ingredients; laboratory animals; lard; low density lipoprotein; males; mixing; phospholipids; pork; protein metabolism; rats; saturated fats; tissue weight; triacylglycerols; very low density lipoprotein;     Show all 26 Subjects
Abstract:
... Restructuring pork (RP) by adding new functional ingredients, like Chia oil (one of the richest natural source of α-linolenic acid) or hydroxytyrosol (HxT) (potent antioxidant), both with hypolipidemic activities, is one of the strategies that may help to reduce the potential negative effects of high meat products consumption. The aim of this study was to evaluate the Chia oil- or HxT-enrich ...
DOI:
10.3390/nu10121830

72. <i>Ishige okamurae</i> Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice

Author:
Seo, Young-Jin; Lee, Kippeum; Song, Ji-Hyeon; Chei, Sungwoo; Lee, Boo-Yong
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Ishige okamurae; animal disease models; atherosclerosis; beta oxidation; blood serum; diacylglycerol acyltransferase; fasting; fatty acid composition; fatty liver; fatty-acid synthase; free fatty acids; gene expression regulation; genes; high fat diet; hyperglycemia; liver; mice; noninsulin-dependent diabetes mellitus; obesity; peroxisome proliferator-activated receptor gamma; protein synthesis; sterols; triacylglycerol lipase; triacylglycerols; white adipose tissue;     Show all 26 Subjects
Abstract:
... Obesity is caused by the expansion of white adipose tissue (WAT), which stores excess triacylglycerol (TG), this can lead to disorders including type 2 diabetes, atherosclerosis, metabolic diseases. Ishige okamurae extract (IOE) is prepared from a brown alga and has anti-oxidative properties. We investigated the detailed mechanisms of the anti-obesity activity of IOE. Treatment with IOE blocked li ...
DOI:
10.3390/nu10111802

73. Gender and Age Stratified Analyses of Nutrient and Dietary Pattern Associations with Circulating Lipid Levels Identify Novel Gender and Age-Specific Correlations

Author:
Jin, Huifeng; Nicodemus-Johnson, Jessie
Source:
Nutrients 2018 v.10 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; age; cardiovascular diseases; children; diet; eating habits; energy intake; fat intake; females; high density lipoprotein cholesterol; low density lipoprotein cholesterol; magnesium; males; nationalities and ethnic groups; nutrient content; nutrients; physical activity; polyunsaturated fatty acids; regression analysis; saturated fatty acids; socioeconomic status; sugars; triacylglycerols; vitamin A;     Show all 24 Subjects
Abstract:
... Dyslipidemia is a precursor to a myriad of cardiovascular diseases in the modern world. Age, gender, and diet are known modifiers of lipid levels, however they are not frequently investigated in subset analyses. Food and nutrient intakes from National Health and Nutrition Examination Study 2001–2013 were used to assess the correlation between lipid levels (high-density lipoprotein (HDL) chol ...
DOI:
10.3390/nu10111760

74. High Fat/High Glucose Diet Induces Metabolic Syndrome in an Experimental Rat Model

Author:
Moreno-Fernández, Silvia; Garcés-Rimón, Marta; Vera, Gema; Astier, Julien; Landrier, Jean François; Miguel, Marta
Source:
Nutrients 2018 v.10 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; ad libitum feeding; animal models; biomarkers; developed countries; energy expenditure; etiology; fructose; genes; glucose; glucose tolerance; high fat diet; hypertension; insulin; laboratory animals; metabolic syndrome; mitochondria; obesity; oxidative stress; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; triacylglycerols;     Show all 23 Subjects
Abstract:
... Metabolic syndrome (MetS) is defined as a constellation of many metabolic disorders such as hypertension, impaired glucose tolerance, dyslipidemia and obesity, being this last disorder a key factor in the etiology of the syndrome. The widespread of MetS in actual society, mainly in developed countries, is becoming an important health problem and is increasing the need to develop new treatments aga ...
DOI:
10.3390/nu10101502

75. Novel Anti-Obesity Properties of <em>Palmaria mollis</em> in Zebrafish and Mouse Models

Author:
Nakayama, Hiroko; Shimada, Yasuhito; Zang, Liqing; Terasawa, Masahiro; Nishiura, Kaoru; Matsuda, Koichi; Toombs, Charles; Langdon, Chris; Nishimura, Norihiro
Source:
Nutrients 2018 v.10 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Danio rerio; Palmaria; Western diets; adipocytes; adipose tissue; adiposity; animal models; beta oxidation; dietary supplements; fatty liver; functional foods; gene expression; gene expression regulation; genes; lipemic effect; lipogenesis; liver; mice; obesity; obesity-related diseases; peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor gamma; taste;     Show all 24 Subjects
Abstract:
... (1) Background: The red seaweed Palmaria mollis (PM), which has a bacon-like taste, is increasingly being included in Western diets. In this study, we evaluate anti-obesity effects of PM using diet-induced obese (DIO) zebrafish and mice models. (2) Methods: We fed PM-containing feed to DIO-zebrafish and mice, and evaluated the anti-obesity effects We also analyzed gene expression changes in their ...
DOI:
10.3390/nu10101401

76. Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects

Author:
Samkani, Amirsalar; Skytte, Mads J.; Thomsen, Mads N.; Astrup, Arne; Deacon, Carolyn F.; Holst, Jens J.; Madsbad, Sten; Rehfeld, Jens F.; Krarup, Thure; Haugaard, Steen B.
Source:
Nutrients 2018 v.10 no.9
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; acute effects; adults; appetite; blood glucose; body mass index; breakfast; cholecystokinin; cross-over studies; dietary carbohydrate; energy; free fatty acids; glucagon; glucagon-like peptide 1; glucose; hemoglobin; hyperinsulinemia; insulin; insulin secretion; islets of Langerhans; lunch; males; noninsulin-dependent diabetes mellitus; satiety; triacylglycerols;     Show all 25 Subjects
Abstract:
... Postprandial responses to food are highly dependent on the macronutrient composition of the diet. We investigated the acute effects of transition from the recommended moderately high carbohydrate (HC) diet towards a carbohydrate-reduced high-protein (CRHP) diet on postprandial glycemia, insulinemia, lipemia, and appetite-regulating hormones in non-diabetic adults. Fourteen subjects, including five ...
DOI:
10.3390/nu10091285

77. The Inhibitory Effect of Ojeoksan on Early and Advanced Atherosclerosis

Author:
Han, Byung Hyuk; Seo, Chang Seob; Yoon, Jung Joo; Kim, Hye Yoom; Ahn, You Mee; Eun, So Young; Hong, Mi Hyeon; Lee, Jae Geon; Shin, Hyeun Kyoo; Lee, Ho Sub; Lee, Yun Jung; Kang, Dae Gill
Source:
Nutrients 2018 v.10 no.9
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; GTP cyclohydrolase I; adhesion; apolipoprotein E; atherosclerosis; blood pressure; endothelial nitric oxide synthase; eosin; glucose; human umbilical vein endothelial cells; hypertension; inflammation; metalloproteinases; mice; microRNA; nitric oxide; non-specific serine/threonine protein kinase; phosphorylation; protective effect; staining; therapeutics; tumor necrosis factor-alpha;     Show all 22 Subjects
Abstract:
... Atherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the beneficial effects of OJS on atherosclerosis in vitro and in vivo. Western-diet-fed apolipoprotein-E gene-deficient mice (ApoE &min ...
DOI:
10.3390/nu10091256

78. Aged Oolong Tea Reduces High-Fat Diet-Induced Fat Accumulation and Dyslipidemia by Regulating the AMPK/ACC Signaling Pathway

Author:
Yuan, Erdong; Duan, Xuefei; Xiang, Limin; Ren, Jiaoyan; Lai, Xingfei; Li, Qiuhua; Sun, Lingli; Sun, Shili
Source:
Nutrients 2018 v.10 no.2
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Western blotting; adipocytes; beta oxidation; blood chemistry; blood serum; energy expenditure; eosin; epididymis; fatty acids; fatty liver; fatty-acid synthase; hepatocytes; high density lipoprotein cholesterol; high fat diet; immunohistochemistry; inducible nitric oxide synthase; inflammation; low density lipoprotein cholesterol; mice; obesity; oolong tea; phosphorylation; signal transduction; triacylglycerols; tumor necrosis factor-alpha; weight loss;     Show all 27 Subjects
Abstract:
... While oolong tea (OT) has been shown to induce weight loss and reduce fat accumulation, the mechanisms remain poorly defined, especially for aged OT. In this study, five groups of mice (n = 9/group) were used including a normal diet with vehicle treatment, and a high-fat diet (HFD) with vehicle or the water extracts from aged OTs (EAOTs, three different storage years) by oral gavage at 1000 mg/kg· ...
DOI:
10.3390/nu10020187

79. A Randomized Double-Blinded, Placebo-Controlled Trial Investigating the Effect of Fish Oil Supplementation on Gene Expression Related to Insulin Action, Blood Lipids, and Inflammation in Gestational Diabetes Mellitus-Fish Oil Supplementation and Gestational Diabetes

Author:
Jamilian, Mehri; Samimi, Mansooreh; Mirhosseini, Naghmeh; Afshar Ebrahimi, Faraneh; Aghadavod, Esmat; Taghizadeh, Mohsen; Asemi, Zatollah
Source:
Nutrients 2018 v.10 no.2
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; blood lipids; cardiovascular diseases; chronic diseases; docosahexaenoic acid; eicosapentaenoic acid; fish oils; gene expression; gene expression regulation; gestational diabetes; inflammation; insulin; insulin resistance; interleukin-1; interleukin-8; low density lipoprotein; low density lipoprotein receptors; mononuclear leukocytes; neoplasms; noninsulin-dependent diabetes mellitus; patients; peroxisome proliferator-activated receptor gamma; placebos; pregnancy; reverse transcriptase polymerase chain reaction; risk reduction; tumor necrosis factor-alpha; women;     Show all 28 Subjects
Abstract:
... Gestational diabetes mellitus (GDM) is a common complication of pregnancy, and it is mostly associated with postpartum diabetes, insulin resistance, and dyslipidemia. Fish oil (omega-3) supplementation has been shown to reduce the risk of different chronic diseases such as cardiovascular disease, type 2 diabetes, and cancers, though the evidence of its impact on gestational diabetes is scarce. Our ...
DOI:
10.3390/nu10020163

80. Effects of Melatonin on Glucose Homeostasis, Antioxidant Ability, and Adipokine Secretion in ICR Mice with NA/STZ-Induced Hyperglycemia

Author:
Lo, Chung-Cheng; Lin, Shyh-Hsiang; Chang, Jung-Su; Chien, Yi-Wen
Source:
Nutrients 2017 v.9 no.11
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adiponectin; antioxidant activity; body weight; diabetes; enzyme activity; glucose; hemostasis; high density lipoprotein cholesterol; homeostasis; hyperglycemia; insulin; leptin; liver; low density lipoprotein cholesterol; malondialdehyde; melatonin; mice; neoplasms; nicotinamide; oxidative stress; secretion; streptozotocin; superoxide dismutase; triacylglycerols;     Show all 25 Subjects
Abstract:
... Diabetes is often associated with decreased melatonin level. The aim was to investigate the effects of different dosage of melatonin on glucose hemostasis, antioxidant ability and adipokines secretion in diabetic institute for cancer research (ICR) mice. Forty animals were randomly divided into five groups including control (C), diabetic (D), low-dosage (L), medium-dosage (M), and high-dosage (H) ...
DOI:
10.3390/nu9111187

81. Fatty Acids Consumption: The Role Metabolic Aspects Involved in Obesity and Its Associated Disorders

Author:
Silva Figueiredo, Priscila; Carla Inada, Aline; Marcelino, Gabriela; Maiara Lopes Cardozo, Carla; de Cássia Freitas, Karine; de Cássia Avellaneda Guimarães, Rita; Pereira de Castro, Alinne; Aragão do Nascimento, Valter; Aiko Hiane, Priscila
Source:
Nutrients 2017 v.9 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adiponectin; atherosclerosis; dietary supplements; docosahexaenoic acid; dysbiosis; eating habits; eicosapentaenoic acid; fatty liver; gene expression; glucose; high density lipoprotein; high fat diet; inflammation; insulin resistance; intestinal microorganisms; lipid metabolism; monounsaturated fatty acids; obesity; palmitic acid; triacylglycerols;     Show all 21 Subjects
Abstract:
... Obesity and its associated disorders, such as insulin resistance, dyslipidemia, metabolic inflammation, dysbiosis, and non-alcoholic hepatic steatosis, are involved in several molecular and inflammatory mechanisms that alter the metabolism. Food habit changes, such as the quality of fatty acids in the diet, are proposed to treat and prevent these disorders. Some studies demonstrated that saturated ...
DOI:
10.3390/nu9101158

82. Could Pomegranate Juice Help in the Control of Inflammatory Diseases?

Author:
Danesi, Francesca; Ferguson, Lynnette R.
Source:
Nutrients 2017 v.9 no.9
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; animal models; anti-inflammatory activity; anti-inflammatory agents; antioxidants; atherosclerosis; clinical trials; diabetes; disease control; fruits; humans; inflammatory bowel disease; neurodegenerative diseases; polyphenols; pomegranate juice; pomegranates; prostatic neoplasms; respiratory tract diseases; rheumatoid arthritis; therapeutics;     Show all 20 Subjects
Abstract:
... Fruits rich in polyphenols, such as pomegranates, have been shown to have health benefits relating to their antioxidant and anti-inflammatory properties. Using data obtained from PubMed and Scopus, this article provides a brief overview of the therapeutic effects of pomegranate on chronic inflammatory diseases (CID) such as inflammatory bowel disease (IBD), rheumatoid arthritis (RA), metabolic and ...
DOI:
10.3390/nu9090958

83. Flavonoid-Rich Extract of <em>Paulownia fortunei</em> Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway

Author:
Liu, Chanmin; Ma, Jieqiong; Sun, Jianmei; Cheng, Chao; Feng, Zhaojun; Jiang, Hong; Yang, Wei
Source:
Nutrients 2017 v.9 no.9
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Paulownia fortunei; animal disease models; blood serum; body weight changes; enzyme activity; enzymes; fatty liver; flowers; glucose; high fat diet; human cell lines; insulin; insulin resistance; lipemic effect; lipid metabolism; lipids; liver; males; mice; obesity; phosphorylation; protective effect;     Show all 23 Subjects
Abstract:
... The flavonoid-rich extract from Paulownia fortunei flowers (EPF) has been reported to prevent obesity and other lipid metabolism disease. However, the mechanism of its protective effects is not yet clear. The objective of this study was to investigate molecular factors involved in the hypoglycemic and hypolipidemic effects of EPF in obese mice fed a high-fat diet (HFD). Male h ICR (Institute of Ca ...
DOI:
10.3390/nu9090959

84. Ferulic Acid on Glucose Dysregulation, Dyslipidemia, and Inflammation in Diet-Induced Obese Rats: An Integrated Study

Author:
Salazar-López, Norma Julieta; Astiazarán-García, Humberto; González-Aguilar, Gustavo A.; Loarca-Piña, Guadalupe; Ezquerra-Brauer, Josafat-Marina; Domínguez Avila, J. Abraham; Robles-Sánchez, Maribel
Source:
Nutrients 2017 v.9 no.7
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; abdominal fat; animal disease models; antioxidant activity; antioxidants; biomarkers; blood lipids; blood serum; body weight changes; ferulic acid; glucose; high fat diet; hyperplasia; hypertrophy; inflammation; laboratory animals; lard; males; obesity; rats; tissues;     Show all 21 Subjects
Abstract:
... Obesity is considered to be a low-grade chronic inflammatory process, which is associated with cardiovascular and metabolic diseases. An integral evaluation of the effects of ferulic acid on biomarkers of glucose dysregulation, dyslipidemia, inflammation, and antioxidant potential induced by a high-fat diet (HFD) in rats was carried out. Three groups of male Wistar rats (six per group) consumed a ...
DOI:
10.3390/nu9070675

85. Seabuckthorn Leaves Extract and Flavonoid Glycosides Extract from Seabuckthorn Leaves Ameliorates Adiposity, Hepatic Steatosis, Insulin Resistance, and Inflammation in Diet-Induced Obesity

Author:
Kwon, Eun-Young; Lee, Jeonghyeon; Kim, Ye Jin; Do, Ara; Choi, Ji-Young; Cho, Su-Jung; Jung, Un Ju; Lee, Mi-Kyung; Park, Yong Bok; Choi, Myung-Sook
Source:
Nutrients 2017 v.9 no.6
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Hippophae rhamnoides; absorption; adipose tissue; adiposity; beta oxidation; cytokines; energy expenditure; enzyme activity; fatty liver; flavonoids; glycosides; high fat diet; inflammation; insulin resistance; leaf extracts; leaves; lipids; lipogenesis; mice; obesity; resistin;     Show all 22 Subjects
Abstract:
... The aim of the current study was to elucidate the effect of seabuckthorn leaves (SL) extract and flavonoid glycosides extract from seabuckthorn leaves (SLG) on diet-induced obesity and related metabolic disturbances, and additionally, to identify whether flavonoid glycosides and other components in SL can exert a possible interaction for the prevention of metabolic diseases by comparing the effect ...
DOI:
10.3390/nu9060569

86. Compliance with Nutritional and Lifestyle Recommendations in 13,000 Patients with a Cardiometabolic Disease from the Nutrinet-Santé Study

Author:
Adriouch, Solia; Lelong, Hélène; Kesse-Guyot, Emmanuelle; Baudry, Julia; Lampuré, Aurélie; Galan, Pilar; Hercberg, Serge; Touvier, Mathilde; Fezeu, Léopold K.
Source:
Nutrients 2017 v.9 no.6
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adults; alcohols; compliance; dairy products; diabetes; dietary recommendations; eating habits; fish; food intake; fruits; healthy diet; hypertension; lifestyle; lipids; patients; physical activity; processed meat; seafoods; sodium; tobacco; vegetables; whole grain foods;     Show all 23 Subjects
Abstract:
... Background: A healthy diet has been shown to prevent cardiovascular diseases complications. The objective of this study was to assess dietary intakes and compliance with nutritional and lifestyle recommendations in French adults diagnosed with hypertension, diabetes, dyslipidaemia or cardiovascular disease compared with healthy individuals. Methods: Data was collected from 26,570 subjects aged 35 ...
DOI:
10.3390/nu9060546

87. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease

Author:
Testai, Lara; Calderone, Vincenzo
Source:
Nutrients 2017 v.9 no.5
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Citrus; bioavailability; citrus juices; clinical trials; coronary vessels; death; dietary supplements; epidemiological studies; fruits; glycosylation; grapefruits; hesperetin; lemons; mechanism of action; medicine; mortality; myocardial infarction; naringenin; oranges; risk factors; signal transduction; therapeutics;     Show all 23 Subjects
Abstract:
... Background- Cardiovascular diseases, including myocardial infarction, dyslipidaemia and coronary artery pathology, are a major cause of illness and death in Western countries. Therefore, identifying effective therapeutic approaches and their cellular signalling pathways is a challenging goal for medicine. In this regard, several epidemiological studies demonstrate a relationship between the intake ...
DOI:
10.3390/nu9050502

88. Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome

Author:
Legeza, Balázs; Marcolongo, Paola; Gamberucci, Alessandra; Varga, Viola; Bánhegyi, Gábor; Benedetti, Angiolo; Odermatt, Alex
Source:
Nutrients 2017 v.9 no.5
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; 11-beta-hydroxysteroid dehydrogenase; NADP (coenzyme); adipocytes; adipose tissue; adiposity; beverages; food intake; fructose; glucocorticoids; health effects assessments; high fructose corn syrup; inflammation; insulin resistance; lifestyle; metabolic syndrome; metabolism; noninsulin-dependent diabetes mellitus; overeating;     Show all 19 Subjects
Abstract:
... The modern Western society lifestyle is characterized by a hyperenergetic, high sugar containing food intake. Sugar intake increased dramatically during the last few decades, due to the excessive consumption of high-sugar drinks and high-fructose corn syrup. Current evidence suggests that high fructose intake when combined with overeating and adiposity promotes adverse metabolic health effects inc ...
DOI:
10.3390/nu9050426

89. Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders

Author:
Peyrol, Julien; Riva, Catherine; Amiot, Marie Josèphe
Source:
Nutrients 2017 v.9 no.3
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Mediterranean diet; adiposity; bioactive compounds; bioavailability; blood glucose; body weight; cell culture; clinical trials; health promotion; hyperglycemia; hypertension; inflammation; insulin resistance; intestinal microorganisms; intestines; lipid composition; metabolic syndrome; oleic acid; oxidative stress; polyphenols; rodents; virgin olive oil;     Show all 23 Subjects
Abstract:
... Virgin olive oil (VOO) constitutes the main source of fat in the Mediterranean diet. VOO is rich in oleic acid, displaying health-promoting properties, but also contains minor bioactive components, especially phenolic compounds. Hydroxytyrosol (HT), the main polyphenol of olive oil, has been reported to be the most bioactive component. This review aims to compile the results of clinical, animal an ...
DOI:
10.3390/nu9030306

90. An  Exercise‐Only Intervention in Obese Fathers Restores Glucose and Insulin Regulation in Conjunction with the Rescue of Pancreatic Islet Cell Morphology and MicroRNA Expression in Male Offspring

Author:
McPherson, Nicole O.; Lane, Michelle; Sandeman, Lauren; Owens, Julie A.; Fullston, Tod
Source:
Nutrients 2017 v.9 no.2
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; adiposity; blood lipids; cell structures; conception; exercise; fathers; females; free fatty acids; glucose; high fat diet; insulin; insulin resistance; islets of Langerhans; lipid content; males; metabolic syndrome; mice; microRNA; muscle tissues; obesity; progeny;     Show all 22 Subjects
Abstract:
... Paternal obesity programs metabolic syndrome in offspring. Low‐impact exercise in obese males improves the metabolic health of female offspring, however whether this occurred in male offspring remained unknown. C57BL/6NHsd (Harlan) mice were fed a control diet (CD; 6% fat, n = 7) or a high‐fat diet (HFD; 21% fat, n = 16) for 18 weeks. After 9 weeks, HFD‐fed mice either remained sedentary (HH, n = ...
DOI:
10.3390/nu9020122

91. Impact of Flavonols on Cardiometabolic Biomarkers: A Meta‐Analysis of Randomized Controlled Human Trials to Explore the Role of Inter‐Individual Variability

Author:
Menezes, Regina; Rodriguez‐Mateos, Ana; Kaltsatou, Antonia; González‐Sarrías, Antonio; Greyling, Arno; Giannaki, Christoforos; Andres‐Lacueva, Cristina; Milenkovic, Dragan; Dumont, Eileen R. Gibney Julie; Schär, Manuel; Garcia‐Aloy, Mar; Palma‐Duran, Susana Alejandra; Ruskovska, Tatjana; Maksimova, Viktorija; Combet, Emilie; Pinto, Paula
Source:
Nutrients 2017 v.9 no.2
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; biomarkers; blood glucose; blood lipids; blood pressure; cardiovascular diseases; epidemiological studies; fasting; flavonols; health status; high density lipoprotein cholesterol; humans; low density lipoprotein cholesterol; meta-analysis; models; normal values; nutrients; physiological response; randomized clinical trials; risk reduction; triacylglycerols; Asia;     Show all 22 Subjects
Abstract:
... Several epidemiological studies have linked flavonols with decreased risk of cardiovascular disease (CVD). However, some heterogeneity in the individual physiological responses to the consumption of these compounds has been identified. This meta‐analysis aimed to study the effect of flavonol supplementation on biomarkers of CVD risk such as, blood lipids, blood pressure and plasma glucose, as well ...
DOI:
10.3390/nu9020117

92. Selection of the Optimal Herbal Compositions of Red Clover and Pomegranate According to Their Protective Effect against Climacteric Symptoms in Ovariectomized Mice

Author:
Kang, Su Jin; Choi, Beom Rak; Kim, Seung Hee; Yi, Hae Yeon; Park, Hye Rim; Song, Chang Hyun; Ku, Sae Kwang; Lee, Young Joon
Source:
Nutrients 2016 v.8 no.8
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Trifolium pratense; abdominal fat; blood serum; bone density; climacteric fruits; estradiol; fatty liver; femur; mice; obesity; osteocalcin; osteoporosis; ovariectomy; pomegranates; protective effect; uterus;     Show all 17 Subjects
Abstract:
... This study aimed to ascertain the optimal range of red clover dry extracts (RC) and dried pomegranate concentrate powder (PCP) to induce anti-climacteric effects. Thus, the dose ranges showing protective effect of mixed formulae consisting of RC and PCP were examined in ovariectomized mice. At 28 days after bilateral ovariectomy (OVX), mixed herbal compositions (RC:PCP = 1:1, 1:2, 1:4, 1:8, 2:1, 4 ...
DOI:
10.3390/nu8080447

93. Impact of Diabetes-Specific Nutritional Formulas versus Oatmeal on Postprandial Glucose, Insulin, GLP-1 and Postprandial Lipidemia

Author:
Mottalib, Adham; Mohd-Yusof, Barakatun-Nisak; Shehabeldin, Mohamed; Pober, David M.; Mitri, Joanna; Hamdy, Osama
Source:
Nutrients 2016 v.8 no.7
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; amino acids; blood sampling; diet therapy; free fatty acids; glucagon-like peptide 1; glucose; glycemic control; insulin; insulin secretion; noninsulin-dependent diabetes mellitus; oatmeal; overweight; patients; triacylglycerols;     Show all 15 Subjects
Abstract:
... Diabetes-specific nutritional formulas (DSNFs) are frequently used as part of medical nutrition therapy for patients with diabetes. This study aims to evaluate postprandial (PP) effects of 2 DSNFs; Glucerna (GL) and Ultra Glucose Control (UGC) versus oatmeal (OM) on glucose, insulin, glucagon-like peptide-1 (GLP-1), free fatty acids (FFA) and triglycerides (TG). After an overnight fast, 22 overwei ...
DOI:
10.3390/nu8070443

94. Nigerian Honey Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Rats

Author:
Erejuwa, Omotayo O.; Nwobodo, Ndubuisi N.; Akpan, Joseph L.; Okorie, Ugochi A.; Ezeonu, Chinonyelum T.; Ezeokpo, Basil C.; Nwadike, Kenneth I.; Erhiano, Erhirhie; Abdul Wahab, Mohd S.; Sulaiman, Siti A.
Source:
Nutrients 2016 v.8 no.3
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; animal disease models; cardiovascular diseases; diabetes; glucose; glycosylation; hemoglobin; high density lipoprotein cholesterol; honey; hyperglycemia; lipemic effect; patients; rats; triacylglycerols; very low density lipoprotein;     Show all 15 Subjects
Abstract:
... Diabetic dyslipidemia contributes to an increased risk of cardiovascular disease. Hence, its treatment is necessary to reduce cardiovascular events. Honey reduces hyperglycemia and dyslipidemia. The reproducibility of these beneficial effects and their generalization to honey samples of other geographical parts of the world remain controversial. Currently, data are limited and findings are inconcl ...
DOI:
10.3390/nu8030095

95. Impact of Nutrition on Cerebral Circulation and Cognition in the Metabolic Syndrome

Author:
Mellendijk, Laura; Wiesmann, Maximilian; Kiliaan, Amanda J.
Source:
Nutrients 2015 v.7 no.11 pp. 9416-9439
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; brain; cognition; cognitive disorders; dementia; disease outbreaks; hyperglycemia; hypertension; metabolic syndrome; noninsulin-dependent diabetes mellitus; nutrition; obesity; stroke;     Show all 13 Subjects
Abstract:
... The increasing prevalence of Metabolic Syndrome (MetS), defined as the clustering of abdominal obesity, dyslipidemia, hypertension, and hyperglycemia, appears to be driving the global epidemics cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Nutrition has a major impact on MetS and plays an important role in the prevention, development, and treatment of its features. Structural a ...
DOI:
10.3390/nu7115477

96. High Consumption of Iron Exacerbates Hyperlipidemia, Atherosclerosis, and Female Sterility in Zebrafish via Acceleration of Glycation and Degradation of Serum Lipoproteins

Author:
Kim, So-Hee; Yadav, Dhananjay; Kim, Suk-Jeong; Kim, Jae-Ryong; Cho, Kyung‐Hyun
Source:
Nutrients 2017 v.9 no.7
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Danio rerio; antioxidant activity; atherosclerosis; blood glucose; blood serum; body weight; cell senescence; cholesterol; diabetes; embryo (animal); fatty liver; female fertility; females; fibroblasts; follicular development; fructose; glycation; high fat diet; hyperglycemia; iron; low density lipoprotein; macrophages; phagocytosis; protein degradation; risk factors; triacylglycerols;     Show all 27 Subjects
Abstract:
... Elevated serum iron level is linked with an increased risk of diabetes and atherosclerosis. However, the pathological mechanism by which iron affects serum lipoprotein levels is unknown. To elucidate the mechanism, a high dose of ferrous ion was applied (final 60 µM, 120 µM) to human serum lipoproteins, macrophages, and human dermal fibroblast (HDF) cells. Iron-treated lipoproteins showed loss of ...
DOI:
10.3390/nu9070690

97. NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet

Author:
Amato, Antonella; Caldara, Gaetano-Felice; Nuzzo, Domenico; Baldassano, Sara; Picone, Pasquale; Rizzo, Manfredi; Mulè, Flavia; Di Carlo, Marta
Source:
Nutrients 2017 v.9 no.5
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Curcuma longa; angiotensinogen; anti-inflammatory activity; aorta; atherogenesis; atherosclerosis; carotid arteries; chlorogenic acid; curcumin; dietary supplements; enzyme-linked immunosorbent assay; fatty liver; free fatty acids; gene expression; gene expression regulation; genes; high fat diet; histology; inflammation; inulin; lipid metabolism; mechanism of action; messenger RNA; mice; oral administration; quantitative polymerase chain reaction; renin-angiotensin system; silymarin;     Show all 29 Subjects
Abstract:
... Non-alcoholic fatty liver disease (NAFLD) confers an increased risk of cardiovascular diseases. NAFDL is associated with atherogenic dyslipidemia, inflammation and renin-angiotensin system (RAS) imbalance, which in turn lead to atherosclerotic lesions. In the present study, the impact of a natural dietary supplement (NDS) containing Curcuma longa, silymarin, guggul, chlorogenic acid and inulin on ...
DOI:
10.3390/nu9050492

98. <em>Plantago asiatica</em> L. Ameliorates Puromycin Aminonucleoside-Induced Nephrotic Syndrome by Suppressing Inflammation and Apoptosis

Author:
Kho, Min Chul; Park, Ji Hun; Han, Byung Hyuk; Tan, Rui; Yoon, Jung Joo; Kim, Hye Yoom; Ahn, You Mee; Lee, Yun Jung; Kang, Dae Gill; Lee, Ho Sub
Source:
Nutrients 2017 v.9 no.4
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; proteinuria; nephrotic syndrome; Plantago asiatica; chemokine CCL2; renoprotective effect; phosphorylation; mitogen-activated protein kinase; mechanism of action; nucleoproteins; intercellular adhesion molecule-1; apoptosis; caspase-3; traditional medicine; blood lipids; ascites; histology; tumor necrosis factor-alpha; adhesion; rats; hypoalbuminemia; intravenous injection; inflammation; laboratory animals; puromycin; animal models; Asia;     Show all 27 Subjects
Abstract:
... Objective: Nephrotic syndrome, a kidney disease with a variety of causes, is mainly characterized by heavy proteinuria, hypoproteinemia, and ascites. This study was designed to evaluate the underlying mechanism of action of Plantago asiatica L. (PAL) in treating nephrotic syndrome induced by puromycin aminonucleoside. Methods: PAL has been used in Asia as a traditional medicine and dietary health ...
DOI:
10.3390/nu9040386

99. Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD)

Author:
Chen, Qian; Wang, Tingting; Li, Jian; Wang, Sijian; Qiu, Feng; Yu, Haiyang; Zhang, Yi; Wang, Tao
Source:
Nutrients 2017 v.9 no.2
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; acetyl-CoA carboxylase; adenosine monophosphate; beverages; binding proteins; cell communication; curcumin; fatty liver; fatty-acid synthase; fructose; insulin resistance; leptin; lipogenesis; liver; metabolic syndrome; mitochondria; mitogen-activated protein kinase; new drugs; peroxisome proliferator-activated receptor alpha; phosphatidylinositol 3-kinase; processed foods; resveratrol; stearoyl-CoA desaturase; sterols; transcription factor NF-kappa B; tumor necrosis factor-alpha;     Show all 26 Subjects
Abstract:
... As a sugar additive, fructose is widely used in processed foods and beverages. Excessive fructose consumption can cause hepatic steatosis and dyslipidemia, leading to the development of metabolic syndrome. Recent research revealed that fructose-induced nonalcoholic fatty liver disease (NAFLD) is related to several pathological processes, including: (1) augmenting lipogenesis; (2) leading to mitoch ...
DOI:
10.3390/nu9020096

100. Prevalence of Metabolic Syndrome among Korean Adolescents According to the National Cholesterol Education Program, Adult Treatment Panel III and International Diabetes Federation

Author:
Kim, Seonho; So, Wi-Young
Source:
Nutrients 2016 v.8 no.10
ISSN:
2072-6643
Subject:
hyperlipidemia,   etc   ; Koreans; National Cholesterol Education Program; adolescents; adults; children; descriptive studies; females; high density lipoprotein cholesterol; hypertension; insulin resistance; males; metabolic syndrome; noninsulin-dependent diabetes mellitus; nutrition; obesity; risk factors; triacylglycerols; Korean Peninsula;     Show all 19 Subjects
Abstract:
... In both adults and children, metabolic syndrome (MetS) has been attributed to risk factors for type 2 diabetes and cardiovascular disease such as insulin resistance, abdominal obesity, hypertension, and dyslipidemia. This descriptive study aimed to compare the prevalence of MetS and diagnostic components according to the National Cholesterol Education Program, Adult Treatment Panel III (NCEP-ATP I ...
DOI:
10.3390/nu8100588