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1. Comparing Two Classifications of Cancer Cachexia and Their Association with Survival in Patients with Unresected Pancreatic Cancer

Author:
Wesseltoft-Rao, Nima; Hjermstad, Marianne J.; Ikdahl, Tone; Dajani, Olav; Ulven, Stine M.; Iversen, Per Ole; Bye, Asta
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 472-480
ISSN:
1532-7914
Subject:
C-reactive protein; anorexia; body mass index; cachexia; computed tomography; food intake; men; pancreatic neoplasms; patients; sarcopenia; weight loss
Abstract:
... There is no universally accepted definition of cancer cachexia. Two classifications have been proposed; the 3-factor classification requiring ≥2 of 3 factors; weight loss ≥10%, food intake ≤1500 kcal/day, and C-reactive protein ≥10 mg/l, and the consensus classification requiring weight loss >5% the past 6 mo, or body mass index <20 kg/m ² or sarcopenia, both with ongoing weight loss >2%. Precache ...
DOI:
10.1080/01635581.2015.1004728

2. Effects of Zinc Sulfate Supplementation on Cell-Mediated Immune Response in Head and Neck Cancer Patients Treated with Radiation Therapy

Author:
Sangthawan, Duangjai; Phungrassami, Temsak; Sinkitjarurnchai, Wattana
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 449-456
ISSN:
1532-7914
Subject:
T-lymphocytes; adverse effects; cell-mediated immunity; head; neck; neoplasms; nutrient deficiencies; patients; placebos; radiotherapy; zinc; zinc sulfate
Abstract:
... Zinc deficiency is an important factor that impairs cellular immunity and contributes to low T lymphocyte counts in head and neck cancers. Persistent T lymphopenia is clinically relevant in terms of tumor persistence and/or recurrence. The primary objective was to evaluate the impact of zinc sulfate supplementation on the absolute numbers of circulating T lymphocytes and T lymphocyte subpopulation ...
DOI:
10.1080/01635581.2015.1004735

3. Individuals with Hematological Malignancies Before Undergoing Chemotherapy Present Oxidative Stress Parameters and Acute Phase Proteins Correlated with Nutritional Status

Author:
Camargo, Carolina de Quadros; Borges, Dayanne da Silva; Oliveira, Paula Fernanda de; Chagas, Thayz Rodrigues; Del Moral, Joanita Angela Gonzaga; Durigon, Giovanna Steffanello; Dias, Bruno Vieira; Vieira, André Guedes; Gaspareto, Patrick; Trindade, Erasmo Benício Santos de Moraes; Nunes, Everson Araújo
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 463-471
ISSN:
1532-7914
Subject:
C-reactive protein; albumins; blood cells; body mass index; catalase; correlation; diet counseling; drug therapy; leukemia; lipid peroxidation; lymphoma; normal values; nutritional status; overweight; oxidative stress; patients; risk; superoxide anion
Abstract:
... Hematological malignancies present abnormal blood cells that may have altered functions. This study aimed to evaluate nutritional status, acute phase proteins, parameters of cell's functionality, and oxidative stress of patients with hematological malignancies, providing a representation of these variables at diagnosis, comparisons between leukemias and lymphomas and establishing correlations. Nut ...
DOI:
10.1080/01635581.2015.1004732

4. L- Arginine Pretreatment Reduces Intestinal Mucositis as Induced by 5-FU in Mice

Author:
Leocádio, Paola C. L.; Antunes, Maísa M.; Teixeira, Lílian G.; Leonel, Alda J.; Alvarez-Leite, Jacqueline I.; Machado, Denise C. C.; Generoso, Simone V.; Cardoso, Valbert N.; Correia, Maria Isabel T. D.
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 486-493
ISSN:
1532-7914
Subject:
adverse effects; arginine; body weight; diarrhea; drug therapy; fluorouracil; histopathology; immune response; inflammation; males; mice; myeloperoxidase; nausea; nutritional status; oxidative stress; pain; patients; permeability; small intestine; vomiting; weight loss
Abstract:
... Beneficial effects of L-arginine on immune responses and bowel function have been reported. Mucositis is a side effect of chemotherapy treatment that affects approximately 40% of patients. This complication is characterized by inflammation that affects the gastrointestinal tract, increasing permeability and causing abdominal pain, nausea, vomiting, and diarrhea, which worsen the patient's nutritio ...
DOI:
10.1080/01635581.2015.1004730

5. Low Pretherapeutic Serum Albumin as a Risk Factor for Poor Outcome in Esophageal Squamous Cell Carcinomas

Author:
Wu, Ning; Chen, Gang; Hu, Huoli; Pang, Liewen; Chen, Zhiming
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 481-485
ISSN:
1532-7914
Subject:
arrhythmia; carcinoma; comorbidity; confidence interval; esophageal neoplasms; females; inflammation; malnutrition; multivariate analysis; patients; risk factors; sepsis (infection); serum albumin; survival rate
Abstract:
... The number of esophageal cancer patients is increasing worldwide and lots of patients suffer from malnutrition and hypoalbuminemic. Serum albumin is a widely acceptable method of assessing nutritional and inflammation status in cancer patients. But whether serum albumin has prognostic value with regard to short-term and long-term outcomes in patients who undergo esophagectomy for cancer is still u ...
DOI:
10.1080/01635581.2015.1004726

6. Perioperative Synbiotics Decrease Postoperative Complications in Periampullary Neoplasms: A Randomized, Double-Blind Clinical Trial

Author:
Sommacal, Heloisa Martins; Bersch, Vivian Pierri; Vitola, Santo Pascoal; Osvaldt, Alessandro Bersch
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 457-462
ISSN:
1532-7914
Subject:
Bifidobacterium bifidum; Lactobacillus acidophilus; Lactobacillus casei; Lactobacillus rhamnosus; antibiotics; clinical trials; fructooligosaccharides; hospitals; morbidity; mortality; neoplasms; nutritional status; patients; postoperative complications; prebiotics; probiotics; prognosis; risk; surgery
Abstract:
... Periampullary neoplasms are rapidly progressive tumors with a poor prognosis and high morbidity and mortality rates, which have a negative influence on patient outcomes. Some probiotics and prebiotics have the ability to protect the intestinal barrier and prevent bacterial translocation, infection, and postoperative complications. We evaluated the use of synbiotics in a prospective, double-blind s ...
DOI:
10.1080/01635581.2015.1004734

7. Serum 25-Hydroxy Vitamin D and Survival in Advanced Colorectal Cancer: A Retrospective Analysis

Author:
Wesa, Kathleen M.; Segal, Neil H.; Cronin, Angel M.; Sjoberg, Daniel D.; Jacobs, Gria N.; Coleton, Marci I.; Fleisher, Martin; Dnistrian, Ann M.; Saltz, Leonard B.; Cassileth, Barrie R.
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 424-430
ISSN:
1532-7914
Subject:
albumins; antigens; blood serum; clinical trials; colorectal neoplasms; confidence interval; patients; regression analysis; repletion; retrospective studies; vitamin D; vitamin D deficiency
Abstract:
... Higher serum 25-hydroxy vitamin D [25(OH)D] levels are associated with decreased colorectal cancer (CRC) incidence. In this retrospective study of Stage IV CRC patients, we evaluate whether 25(OH)D levels at diagnosis correlate with survival. Stored sera from carcinoembryonic antigen (CEA) measurements obtained between February 2005 and March 2006 were screened. The first 250 patients with CEA ±30 ...
DOI:
10.1080/01635581.2015.998838
PubMed:
25646565
PubMed Central:
PMC4385477