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You searched for: Journal Nutrition and cancer Remove constraint Journal: Nutrition and cancer Publication Year 2015 Remove constraint Publication Year: 2015 Source 2015 v.67 no.3 Remove constraint Source: 2015 v.67 no.3
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1. Akt Signaling Is Associated with the Berberine-Induced Apoptosis of Human Gastric Cancer Cells

Author:
Yi, Tingting; Zhuang, Luhua; Song, Gang; Zhang, Bing; Li, Guideng; Hu, Tianhui
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 523-531
ISSN:
1532-7914
Subject:
NAD ADP-ribosyltransferase; antineoplastic agents; apoptosis; berberine; caspase-3; humans; membrane potential; mice; mitochondrial membrane; neoplasm cells; stomach neoplasms
Abstract:
... Despite extensive studies on the antitumor properties of berberine, a small molecule derived from Coptidis rhizoma (Huanglian in Chinese) and many other plants, the underlying mechanism remains poorly understood. Here, we found that berberine-induced cell apoptosis in human gastric cancer cells with the increase of the expression level of cleaved poly ADP-ribose polymerase and caspase-3, and the i ...
DOI:
10.1080/01635581.2015.1004733

2. Breastfeeding and Nutrition to 2 Years of Age and Risk of Childhood Acute Lymphoblastic Leukemia and Brain Tumors

Author:
Greenop, Kathryn R.; Bailey, Helen D.; Miller, Margaret; Scott, Rodney J.; Attia, John; Ashton, Lesley J.; Downie, Peter; Armstrong, Bruce K.; Milne, Elizabeth
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 431-441
ISSN:
1532-7914
Subject:
bottle feeding; brain; breast feeding; case-control studies; childhood; confidence interval; diet; etiology; infant feeding; lymphocytic leukemia; mothers; odds ratio; questionnaires; regression analysis; risk; risk reduction
Abstract:
... Acute lymphoblastic leukemia (ALL) and childhood brain tumors (CBT) are 2 of the most common forms of childhood cancer, but little is known of their etiology. In 2 nationwide case-control studies we investigated whether breastfeeding, age of food introduction, or early diet are associated with the risk of these cancers. Cases aged 0–14 years were identified from Australian pediatric oncology units ...
DOI:
10.1080/01635581.2015.998839

3. Coffee Consumption and Prostate Cancer Risk: A Meta-Analysis of Cohort Studies

Author:
Liu, Huan; Hu, Guang-Hui; Wang, Xing-Chun; Huang, Tian-Bao; Xu, Liang; Lai, Peng; Guo, Zhui-Feng; Xu, Yun-Fei
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 392-400
ISSN:
1532-7914
Subject:
risk; prospective studies; dose response; meta-analysis; confidence interval; prostatic neoplasms; risk reduction
Abstract:
... This meta-analysis was conducted to assess the association between coffee consumption and prostate cancer risk. Thirteen cohort studies with 34,105 cases and 539,577 participants were included in the meta-analysis. The summary relative risks (RRs) with 95% confidence intervals (CIs) for different coffee intake levels were calculated. Dose-response relationship was assessed using generalized least ...
DOI:
10.1080/01635581.2015.1004727

4. Comparing Two Classifications of Cancer Cachexia and Their Association with Survival in Patients with Unresected Pancreatic Cancer

Author:
Wesseltoft-Rao, Nima; Hjermstad, Marianne J.; Ikdahl, Tone; Dajani, Olav; Ulven, Stine M.; Iversen, Per Ole; Bye, Asta
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 472-480
ISSN:
1532-7914
Subject:
C-reactive protein; anorexia; body mass index; cachexia; computed tomography; food intake; men; pancreatic neoplasms; patients; sarcopenia; weight loss
Abstract:
... There is no universally accepted definition of cancer cachexia. Two classifications have been proposed; the 3-factor classification requiring ≥2 of 3 factors; weight loss ≥10%, food intake ≤1500 kcal/day, and C-reactive protein ≥10 mg/l, and the consensus classification requiring weight loss >5% the past 6 mo, or body mass index <20 kg/m ² or sarcopenia, both with ongoing weight loss >2%. Precache ...
DOI:
10.1080/01635581.2015.1004728

5. 2-Deoxyglucose Induces Cell Cycle Arrest and Apoptosisin Colorectal Cancer Cells Independent of Its Glycolysis Inhibition

Author:
Muley, Pratik; Olinger, Alex; Tummala, Hemachand
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 514-522
ISSN:
1532-7914
Subject:
2-deoxyglucose; adenosine triphosphate; antineoplastic agents; apoptosis; cell cycle checkpoints; colorectal neoplasms; drug therapy; glycolysis; hexokinase; interphase; neoplasm cells
Abstract:
... 2-Deoxyglucose (2DG) is an anticancer drug with excellent safety profile. Because of its higher dose requirements, its potential is yet to translate into a monotherapy. However, recently, 2DG has been tested as an adjunct in established chemotherapeutic regimens. 2DG enhanced the potency of several chemotherapeutic agents but not all. The rationale selection of known chemotherapeutic agents to use ...
DOI:
10.1080/01635581.2015.1002626

6. Effects of Caffeic and 5-Caffeoylquinic Acids on Cell Viability and Cellular Uptake in Human Colon Adenocarcinoma Cells

Author:
Murad, Luana Dalbem; Soares, Nathalia da Costa Pereira; Brand, Camila; Monteiro, Mariana Costa; Teodoro, Anderson Junger
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 532-542
ISSN:
1532-7914
Subject:
adenocarcinoma; apoptosis; caffeic acid; cell cycle; cell growth; cell viability; chronic diseases; colon; colorectal neoplasms; diet; flow cytometry; high performance liquid chromatography; humans; isomerization; morbidity; mortality; risk reduction
Abstract:
... Colorectal cancer is a major cause of morbidity and mortality throughout the world. Issues related to the role of diet in cancer prevention and treatment are featured each year, and, in this context, consumption of hydroxycinanmic acids is associated with reduced risk of chronic diseases including cancer. Therefore, the aim of this study was to evaluate the cellular uptake of caffeic and 5-caffeoy ...
DOI:
10.1080/01635581.2015.1004736

7. Effects of Zinc Sulfate Supplementation on Cell-Mediated Immune Response in Head and Neck Cancer Patients Treated with Radiation Therapy

Author:
Sangthawan, Duangjai; Phungrassami, Temsak; Sinkitjarurnchai, Wattana
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 449-456
ISSN:
1532-7914
Subject:
T-lymphocytes; adverse effects; cell-mediated immunity; head; neck; neoplasms; nutrient deficiencies; patients; placebos; radiotherapy; zinc; zinc sulfate
Abstract:
... Zinc deficiency is an important factor that impairs cellular immunity and contributes to low T lymphocyte counts in head and neck cancers. Persistent T lymphopenia is clinically relevant in terms of tumor persistence and/or recurrence. The primary objective was to evaluate the impact of zinc sulfate supplementation on the absolute numbers of circulating T lymphocytes and T lymphocyte subpopulation ...
DOI:
10.1080/01635581.2015.1004735

8. Individuals with Hematological Malignancies Before Undergoing Chemotherapy Present Oxidative Stress Parameters and Acute Phase Proteins Correlated with Nutritional Status

Author:
Camargo, Carolina de Quadros; Borges, Dayanne da Silva; Oliveira, Paula Fernanda de; Chagas, Thayz Rodrigues; Del Moral, Joanita Angela Gonzaga; Durigon, Giovanna Steffanello; Dias, Bruno Vieira; Vieira, André Guedes; Gaspareto, Patrick; Trindade, Erasmo Benício Santos de Moraes; Nunes, Everson Araújo
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 463-471
ISSN:
1532-7914
Subject:
C-reactive protein; albumins; blood cells; body mass index; catalase; correlation; diet counseling; drug therapy; leukemia; lipid peroxidation; lymphoma; normal values; nutritional status; overweight; oxidative stress; patients; risk; superoxide anion
Abstract:
... Hematological malignancies present abnormal blood cells that may have altered functions. This study aimed to evaluate nutritional status, acute phase proteins, parameters of cell's functionality, and oxidative stress of patients with hematological malignancies, providing a representation of these variables at diagnosis, comparisons between leukemias and lymphomas and establishing correlations. Nut ...
DOI:
10.1080/01635581.2015.1004732

9. L- Arginine Pretreatment Reduces Intestinal Mucositis as Induced by 5-FU in Mice

Author:
Leocádio, Paola C. L.; Antunes, Maísa M.; Teixeira, Lílian G.; Leonel, Alda J.; Alvarez-Leite, Jacqueline I.; Machado, Denise C. C.; Generoso, Simone V.; Cardoso, Valbert N.; Correia, Maria Isabel T. D.
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 486-493
ISSN:
1532-7914
Subject:
adverse effects; arginine; body weight; diarrhea; drug therapy; fluorouracil; histopathology; immune response; inflammation; males; mice; myeloperoxidase; nausea; nutritional status; oxidative stress; pain; patients; permeability; small intestine; vomiting; weight loss
Abstract:
... Beneficial effects of L-arginine on immune responses and bowel function have been reported. Mucositis is a side effect of chemotherapy treatment that affects approximately 40% of patients. This complication is characterized by inflammation that affects the gastrointestinal tract, increasing permeability and causing abdominal pain, nausea, vomiting, and diarrhea, which worsen the patient's nutritio ...
DOI:
10.1080/01635581.2015.1004730

10. Low Pretherapeutic Serum Albumin as a Risk Factor for Poor Outcome in Esophageal Squamous Cell Carcinomas

Author:
Wu, Ning; Chen, Gang; Hu, Huoli; Pang, Liewen; Chen, Zhiming
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 481-485
ISSN:
1532-7914
Subject:
arrhythmia; carcinoma; comorbidity; confidence interval; esophageal neoplasms; females; inflammation; malnutrition; multivariate analysis; patients; risk factors; sepsis (infection); serum albumin; survival rate
Abstract:
... The number of esophageal cancer patients is increasing worldwide and lots of patients suffer from malnutrition and hypoalbuminemic. Serum albumin is a widely acceptable method of assessing nutritional and inflammation status in cancer patients. But whether serum albumin has prognostic value with regard to short-term and long-term outcomes in patients who undergo esophagectomy for cancer is still u ...
DOI:
10.1080/01635581.2015.1004726

11. Natural Grape Extracts Regulate Colon Cancer Cells Malignancy

Author:
Signorelli, Paola; Fabiani, Carlotta; Brizzolari, Andrea; Paroni, Rita; Casas, Josefina; Fabriàs, Gemma; Rossi, Dario; Ghidoni, Riccardo; Caretti, Anna
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 494-503
ISSN:
1532-7914
Subject:
anthocyanins; antioxidants; cadherins; cell cycle checkpoints; colorectal neoplasms; digestive tract; drug therapy; epithelium; freeze drying; grapes; homeostasis; inflammation; neoplasm cells; polyphenols; red wines; sphingolipids; transcription factors; transcriptional activation
Abstract:
... Natural dietary components are evolutionary-selected molecules able to control inflammation and cancerous transformation and progression. Because many studies assessed the beneficial properties of key molecules extracted from grapes, we aimed at investigating the properties of Liofenol™, a natural red wine lyophilized extract, devoid of alcohol and composed by a miscellaneous of components (polyph ...
DOI:
10.1080/01635581.2015.1004591

12. Natural Product Modulators to Overcome Multidrug Resistance In Cancer

Author:
Cort, Aysegul; Ozben, Tomris
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 411-423
ISSN:
1532-7914
Subject:
ABC transporters; active sites; binding agents; cytotoxicity; drug therapy; drugs; mechanism of action; multiple drug resistance; nanoparticles; neoplasms; researchers
Abstract:
... Multidrug resistance (MDR) is a condition that makes cells simultaneously unresponsive to different drugs, unrelated to their chemical structure and mechanism of action. MDR caused by the presence and overexpression of ABC transporters makes obstacles in cancer treatment and lower the effectiveness of chemotherapy. Natural products are investigated by many researchers as MDR modulators for their l ...
DOI:
10.1080/01635581.2015.1002624

13. Nutrient and Nonnutrient Components of Legumes, and Its Chemopreventive Activity: A Review

Author:
Sánchez-Chino, Xariss; Jiménez-Martínez, Cristian; Dávila-Ortiz, Gloria; Álvarez-González, Isela; Madrigal-Bujaidar, Eduardo
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 401-410
ISSN:
1532-7914
Subject:
absorption; animal models; antilipemic agents; antineoplastic agents; antioxidants; azoxymethane; carbohydrates; carcinogenesis; carcinogens; chemoprevention; chickpeas; colon; colorectal neoplasms; diet; essential amino acids; hypoglycemic agents; lentils; limiting amino acids; mechanism of action; nutrients; proteins; seeds; soybeans; therapeutics
Abstract:
... Legumes in combination with other products are the staple food for a large part of the world population, especially the low-income fragment, because their seeds provide valuable amounts of carbohydrates, fiber, and proteins, and have an important composition of essential amino acids, the sulphured amino acids being the limiting ones. Furthermore, legumes also have nonnutritional compounds that may ...
DOI:
10.1080/01635581.2015.1004729

14. Perioperative Synbiotics Decrease Postoperative Complications in Periampullary Neoplasms: A Randomized, Double-Blind Clinical Trial

Author:
Sommacal, Heloisa Martins; Bersch, Vivian Pierri; Vitola, Santo Pascoal; Osvaldt, Alessandro Bersch
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 457-462
ISSN:
1532-7914
Subject:
Bifidobacterium bifidum; Lactobacillus acidophilus; Lactobacillus casei; Lactobacillus rhamnosus; antibiotics; clinical trials; fructooligosaccharides; hospitals; morbidity; mortality; neoplasms; nutritional status; patients; postoperative complications; prebiotics; probiotics; prognosis; risk; surgery
Abstract:
... Periampullary neoplasms are rapidly progressive tumors with a poor prognosis and high morbidity and mortality rates, which have a negative influence on patient outcomes. Some probiotics and prebiotics have the ability to protect the intestinal barrier and prevent bacterial translocation, infection, and postoperative complications. We evaluated the use of synbiotics in a prospective, double-blind s ...
DOI:
10.1080/01635581.2015.1004734

15. Serum 25-Hydroxy Vitamin D and Survival in Advanced Colorectal Cancer: A Retrospective Analysis

Author:
Wesa, Kathleen M.; Segal, Neil H.; Cronin, Angel M.; Sjoberg, Daniel D.; Jacobs, Gria N.; Coleton, Marci I.; Fleisher, Martin; Dnistrian, Ann M.; Saltz, Leonard B.; Cassileth, Barrie R.
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 424-430
ISSN:
1532-7914
Subject:
albumins; antigens; blood serum; clinical trials; colorectal neoplasms; confidence interval; patients; regression analysis; repletion; retrospective studies; vitamin D; vitamin D deficiency
Abstract:
... Higher serum 25-hydroxy vitamin D [25(OH)D] levels are associated with decreased colorectal cancer (CRC) incidence. In this retrospective study of Stage IV CRC patients, we evaluate whether 25(OH)D levels at diagnosis correlate with survival. Stored sera from carcinoembryonic antigen (CEA) measurements obtained between February 2005 and March 2006 were screened. The first 250 patients with CEA ±30 ...
DOI:
10.1080/01635581.2015.998838
PubMed:
25646565
PubMed Central:
PMC4385477

16. The Association Between Circulating Total Folate and Folate Vitamers With Overall Survival After Postmenopausal Breast Cancer Diagnosis

Author:
McEligot, Archana Jaiswal; Ziogas, Argyrios; Pfeiffer, Christine M.; Fazili, Zia; Anton-Culver, Hoda
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 442-448
ISSN:
1532-7914
Subject:
alcohols; body mass index; breast neoplasms; confidence interval; diet; energy intake; hormone replacement therapy; models; postmenopause; prognosis; relative risk; tetrahydrofolic acid; women
Abstract:
... We studied the relationship between plasma total folate and folate vitamer concentrations [5-methyltetrahydrofolic acid, pteroylglutamic acid (folic acid) and tetrahydrofolic acid] with overall survival after breast cancer diagnosis. A secondary aim was to assess the relationship between folic acid supplement use with circulating total folate and folate vitamer concentrations. Participants were po ...
DOI:
10.1080/01635581.2015.1002623
PubMed:
25647689
PubMed Central:
PMC4385432

17. The Chemopreventive Effect of the Dietary Compound Kaempferol on the MCF-7 Human Breast Cancer Cell Line Is Dependent on Inhibition of Glucose Cellular Uptake

Author:
Azevedo, Cláudia; Correia-Branco, Ana; Araújo, João R.; Guimarães, João T.; Keating, Elisa; Martel, Fátima
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 504-513
ISSN:
1532-7914
Subject:
breast neoplasms; chemoprevention; cytochalasin B; cytotoxicity; genistein; glucose; humans; inhibitory concentration 50; kaempferol; lactate dehydrogenase; messenger RNA; myricetin; neoplasm cells; phloridzin; polyphenols; resveratrol
Abstract:
... Our aim was to investigate the effect of several dietary polyphenols on glucose uptake by breast cancer cells. Uptake of ³H-deoxy-D-glucose (³H-DG) by MCF-7 cells was time-dependent, saturable, and inhibited by cytochalasin B plus phloridzin. In the short-term (26 min), myricetin, chrysin, genistein, resveratrol, kaempferol, and xanthohumol (10–100 µM) inhibited ³H-DG uptake. Kaempferol was found ...
DOI:
10.1080/01635581.2015.1002625

18. The Impact of Complementary and Alternative Medicines on Cancer Symptoms, Treatment Side Effects, Quality of Life, and Survival in Women With Breast Cancer—A Systematic Review

Author:
Leggett, S.; Koczwara, B.; Miller, M.
Source:
Nutrition and cancer 2015 v.67 no.3 pp. 373-391
ISSN:
1532-7914
Subject:
Ganoderma lucidum; adverse effects; breast neoplasms; databases; dietitians; glutamine; mortality; oral administration; powders; quality of life; randomized clinical trials; systematic review; toxicity; women
Abstract:
... Breast cancer is the most common form of cancer amongst women. Women with breast cancer frequently consult dietitians for advice, and increasingly advice on complementary alternative medicines (CAM). The aim of this systematic review was to evaluate evidence of CAM administered orally on cancer-related outcomes. Databases were searched for studies recruiting women with a history of breast cancer r ...
DOI:
10.1080/01635581.2015.1004731