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- Author:
- Biel, Rita K.; Friedenreich, Christine M.; Csizmadi, Ilona; Robson, Paula J.; McLaren, Lindsay; Faris, Peter; Courneya, Kerry S.; Magliocco, Anthony M.; Cook, Linda S.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 673-686
- ISSN:
- 1532-7914
- Subject:
- body mass index; case-control studies; eating habits; endometrium; food analysis; food frequency questionnaires; meat; models; nutrients; overweight; regression analysis; risk; risk reduction; sweets; variance; women; Alberta
- Abstract:
- ... Dietary patterns, rather than intakes of specific foods or nutrients, may influence risk of endometrial cancer (EC). This population-based case-control study in Canada (2002–2006) included incident EC cases (n = 506) from the Alberta Cancer Registry and controls frequency age-matched to cases (n = 981). Past-year dietary patterns were defined using factor analysis of food frequency questionnaire d ...
- DOI:
- 10.1080/01635581.2011.563025
-
http://dx.doi.org/10.1080/01635581.2011.563025
- Author:
- De Stefani, Eduardo; Ronco, Alvaro L.; Deneo-Pellegrini, Hugo; Correa, Pelayo; Boffetta, Paolo; Acosta, Gisele; Mendilaharsu, María
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 699-706
- ISSN:
- 1532-7914
- Subject:
- adenocarcinoma; case-control studies; diet study techniques; eating habits; food analysis; food groups; lung neoplasms; males; men; milk; risk; vegetables; Uruguay
- Abstract:
- ... In the period 1996–2004, a hospital-based case-control study on diet and adenocarcinoma of the lung in men was conducted in Montevideo, Uruguay. The study included 200 cases and 800 controls, frequency matched on age, residence, and interviewers. Factor analysis (principal components) was used to identify the major food patterns associated with adenocarcinoma. The analysis of food groups led to th ...
- DOI:
- 10.1080/01635581.2011.563033
-
http://dx.doi.org/10.1080/01635581.2011.563033
- Author:
- Tam, Carolyn Y.; Hislop, Gregory; Hanley, Anthony J.; Minkin, Salomon; Boyd, Norman F.; Martin, Lisa J.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 687-698
- ISSN:
- 1532-7914
- Subject:
- Canadians; Whites; fish; nutrients; alcohols; beverages; sweets; women; biomarkers; food recalls; postmenopause; energy; meat; risk factors; grains; dairy products; cross-sectional studies; food intake; vegetables; breast neoplasms; Canada; China
- Abstract:
- ... International differences in breast cancer rates and diet, and studies in migrants, suggest that diet may be a modifiable risk factor for breast cancer. The goal of this cross-sectional study was to examine the dietary intakes of women from populations considered to be at different risks for breast cancer. We collected four 24-h food recalls in 3 groups of postmenopausal Canadian women: Caucasians ...
- DOI:
- 10.1080/01635581.2011.563026
-
http://dx.doi.org/10.1080/01635581.2011.563026
- Author:
- Wirfält, Elisabet; Li, Cairu; Manjer, Jonas; Ericson, Ulrika; Sonestedt, Emily; Borgquist, Signe; Landberg, Göran; Olsson, Håkan; Gullberg, Bo
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 722-733
- ISSN:
- 1532-7914
- Subject:
- breast neoplasms; eggs; estrogen receptors; food intake; margarine; milk; multivariate analysis; postmenopause; progesterone receptors; risk; sauces; soups; women; yogurt
- Abstract:
- ... We examined associations between food intakes and incident breast cancer, defined by estrogen receptor (ER) and progesterone receptor (PR) status in the Malmö Diet and Cancer cohort (∼17,000 women aged 45–73 yr). The hazard ratios (HRs) of ER+PR+ (n = 270), ER+PR− (n = 87), and ER−PR− (n = 61) tumors and all cancer (n = 544) were estimated after 10 yr of follow-up. In multivariate analysis of ER+P ...
- DOI:
- 10.1080/01635581.2011.570897
-
http://dx.doi.org/10.1080/01635581.2011.570897
- Author:
- Hajizadeh, Bahareh; Jessri, Mahsa; Moasheri, Seyed Majid; Houshiar Rad, Anahita; Rashidkhani, Bahram
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 707-713
- ISSN:
- 1532-7914
- Subject:
- bananas; body mass index; case-control studies; confidence interval; education; food frequency questionnaires; food groups; fruit consumption; fruits; interviews; oranges; patients; regression analysis; risk; risk reduction; squamous cell carcinoma; tobacco; vegetable consumption; Iran
- Abstract:
- ... The authors examined the association of food group intakes and the risk of esophageal squamous cell carcinoma (SCC) in a hospital-based case-control study in Iran. In total, 47 patients with esophageal SCC and 96 controls underwent face-to-face private interviews. Usual dietary intake was assessed using a semiquantitative food frequency questionnaire. Multivariate logistic regression was used to e ...
- DOI:
- 10.1080/01635581.2011.563028
-
http://dx.doi.org/10.1080/01635581.2011.563028
- Author:
- Zheng, Jusheng; Yang, Bin; Huang, Tao; Yu, Yinghua; Yang, Jing; Li, Duo
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 663-672
- ISSN:
- 1532-7914
- Subject:
- Asians; black tea; case-control studies; cohort studies; confidence interval; databases; green tea; meta-analysis; models; observational studies; prostatic neoplasms; protective effect; risk; Asia
- Abstract:
- ... Observational studies on tea consumption and prostate cancer (PCa) risk are still inconsistent. The authors conducted a meta-analysis to investigate the association between green tea and black tea consumption with PCa risk. Thirteen studies providing data on green tea or black tea consumption were identified by searching PubMed and ISI Web of Science databases and secondary referencing qualified f ...
- DOI:
- 10.1080/01635581.2011.570895
-
http://dx.doi.org/10.1080/01635581.2011.570895
- Author:
- Arthur, Anna E.; Duffy, Sonia A.; Sanchez, Gloria I.; Gruber, Stephen B.; Terrell, Jeffrey E.; Hebert, James R.; Light, Emily; Bradford, Carol R.; D’Silva, Nisha J.; Carey, Thomas E.; Wolf, Gregory T.; Peterson, Karen E.; Rozek, Laura S.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 734-742
- ISSN:
- 1532-7914
- Subject:
- Papillomaviridae; beta-carotene; body mass index; diet; drinking; energy intake; folic acid; genotyping; head; humans; iron; mouth; patients; pharynx; prognosis; regression analysis; squamous cell carcinoma; vitamin A; vitamin E; Michigan
- Abstract:
- ... No studies have investigated dietary differences between head and neck squamous cell carcinoma (HNSCC) patients with human papillomavirus (HPV)-positive tumors and patients with HPV-negative tumors. This study was designed to investigate the relationship between diet and HPV status in HNSCC patients. Cases of HNSCC were recruited from 2 clinical centers participating in the University of Michigan ...
- DOI:
- 10.1080/01635581.2011.570894
- PubMed:
- 21667401
- PubMed Central:
- PMC3391594
-
http://dx.doi.org/10.1080/01635581.2011.570894
- Author:
- Inoue, Akiko; Takitani, Kimitaka; Koh, Maki; Kawakami, Chihiro; Kuno, Tomoko; Tamai, Hiroshi
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 763-770
- ISSN:
- 1532-7914
- Subject:
- anti-inflammatory activity; anticarcinogenic activity; antioxidants; apoptosis; carcinoma; caspases; cytochrome c; cytotoxicity; gamma-tocotrienol; humans; leukemia; patients
- Abstract:
- ... Tocotrienols (Toc3) have been suggested to possess anticancer effects besides antioxidant and antiinflammatory effects. Previous studies have demonstrated that Toc3 induce apoptosis in epithelial carcinoma. However, the effects of Toc3 on malignant hematopoietic cells have not yet been thoroughly investigated. We investigated Toc3-induced apoptosis in human hematological cancer cell lines. α-, δ-, ...
- DOI:
- 10.1080/01635581.2011.563030
-
http://dx.doi.org/10.1080/01635581.2011.563030
- Author:
- Agrawal, Satyam Kumar; Agrawal, Madhunika; Sharma, Parduman Raj; Gupta, Bishan Datt; Arora, Saroj; Saxena, Ajit Kumar
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 802-813
- ISSN:
- 1532-7914
- Subject:
- mitochondrial membrane; cell cycle; DNA fragmentation; Erythrina; caspase-9; cell viability; fluorescence microscopy; humans; leukemia; membrane potential; cell proliferation; cytochrome c; shrinkage; chromatin; bark; apoptosis; caspase-3
- Abstract:
- ... In this study, the apoptosis-inducing effect of an alcoholic extract from Erythrina suberosa stem bark (ESB) was investigated using human promyelocytic leukemia HL60 cells. Cell viability was estimated by MTT assay. We found that the ESB inhibited cell proliferation in a dose- and time-dependent manner. A series of well-documented morphological changes, such as cell shrinkage, condensation of nucl ...
- DOI:
- 10.1080/01635581.2011.573900
-
http://dx.doi.org/10.1080/01635581.2011.573900
- Author:
- Saati, George E.; Archer, Michael C.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 790-794
- ISSN:
- 1532-7914
- Subject:
- Brassica; anticarcinogenic activity; breast neoplasms; epithelial cells; fatty-acid synthase; humans; indoles; lipogenesis; stomach; transcription factors; vegetables
- Abstract:
- ... The putative cancer preventive agent 3,3′-diindolylmethane (DIM) is formed in the acidic environment of the stomach following consumption of indole-3-carbinol (I3C), which is present in vegetables of the Brassica genus. We have recently shown that the transcription factor Sp1 is involved in the regulation of both proliferation and de novo lipogenesis in cancer cells. Here we show that DIM inhibits ...
- DOI:
- 10.1080/01635581.2011.570896
-
http://dx.doi.org/10.1080/01635581.2011.570896
- Author:
- Pink, Ryan C.; Bailey, Tracey A.; Iputo, Jehu E.; Sammon, Alastair M.; Woodman, Anthony C.; Carter, David R.F.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 714-721
- ISSN:
- 1532-7914
- Subject:
- Africans; carcinoma; cell division; cell proliferation; corn; diet; disease incidence; esophageal neoplasms; esophagus; gastric juice; linoleic acid; prostaglandins; risk factors; South Africa
- Abstract:
- ... The incidence of squamous cancer of the esophagus varies up to a hundredfold in different regions of the world. In Transkei, South Africa, a particularly high incidence of the disease is observed. We have previously proposed an association between a maize-rich diet and elevated levels of intragastric prostaglandin E2 production (PGE₂). Here we investigate the molecular mechanisms by which a high-m ...
- DOI:
- 10.1080/01635581.2011.570893
-
http://dx.doi.org/10.1080/01635581.2011.570893
- Author:
- Zhang, Jinhui; Wang, Lei; Li, Guangxun; Anderson, Lorraine B.; Xu, Yanji; Witthuhn, Bruce; Lü, Junxuan
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 778-789
- ISSN:
- 1532-7914
- Subject:
- energy metabolism; fatty-acid synthase; heat stress; mice; models; prostatic neoplasms; proteome; risk; risk reduction; selenium; selenomethionine; vimentin
- Abstract:
- ... We have shown that, in contrast to selenomethionine (SeMet) or selenite, methylseleninic acid (MSeA) and Se-methylselenocysteine (MSeC) exert prostate cancer (PCa) inhibitory effect in preclinical models. Here we investigated the prostate proteome signatures of mice treated with each selenium (Se) form for hypothesis generation concerning their potential in vivo molecular targets and cancer risk m ...
- DOI:
- 10.1080/01635581.2011.563029
-
http://dx.doi.org/10.1080/01635581.2011.563029
- Author:
- Friedrichs, William; Ruparel, Shivani B.; Marciniak, Robert A.; deGraffenried, Linda
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 771-777
- ISSN:
- 1532-7914
- Subject:
- androgen receptors; arachidonic acid; cell growth; docosahexaenoic acid; eicosapentaenoic acid; models; nutritional intervention; omega-3 fatty acids; prostatic neoplasms; signal transduction
- Abstract:
- ... Currently, progression of prostate cancer to androgen independence remains the primary obstacle to improved survival. In order to improve overall survival, novel treatment strategies that are based upon specific molecular mechanisms that prolong the androgen-dependent state and that are useful for androgen-independent disease need to be identified. Both epidemiological as well as preclinical data ...
- DOI:
- 10.1080/01635581.2011.570892
-
http://dx.doi.org/10.1080/01635581.2011.570892
- Author:
- Shadfar, Scott; Couch, Marion E.; McKinney, Kibwei A.; Weinstein, Lisa J.; Yin, Xiaoying; Rodríguez, Jessica E.; Guttridge, Denis C.; Willis, Monte
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 749-762
- ISSN:
- 1532-7914
- Subject:
- transcription factors; grapes; interleukin-1; heart failure; adenocarcinoma; cachexia; muscular dystrophy; interleukin-6; proteolysis; muscular atrophy; sarcomeres; skeletal muscle; therapeutics; animal models; resveratrol; receptors; phytoalexins
- Abstract:
- ... The mechanism by which cancer mediates muscle atrophy has been delineated in the past 3 decades and includes a prominent role of tumor-derived cytokines, such as IL-6, TNFα, and IL-1. These cytokines interact with their cognate receptors on muscle to activate the downstream transcription factor NF-κB and induce sarcomere proteolysis. Experimentally, inhibiting NF-κB signaling largely prevents canc ...
- DOI:
- 10.1080/01635581.2011.563032
- PubMed:
- 21660860
- PubMed Central:
- PMC3623008
-
http://dx.doi.org/10.1080/01635581.2011.563032
- Author:
- Dai, Yumin; Hogan, Shelly; Schmelz, Eva M.; Ju, Young H.; Canning, Corene; Zhou, Kequan
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 795-801
- ISSN:
- 1532-7914
- Subject:
- apoptosis; breast neoplasms; cell cycle; diet; drug resistance; epidermal growth factor receptors; epithelial cells; fruit extracts; gene overexpression; growth retardation; humans; inhibitory concentration 50; messenger RNA; mice; mitogen-activated protein kinase; models; nutritional intervention; oncogenes; prognosis; protective effect; protein synthesis; signal transduction; women
- Abstract:
- ... The epidermal growth factor receptor (EGFR) is an oncogene frequently overexpressed in breast cancer (BC), and its overexpression has been associated with poor prognosis and drug resistance. EGFR is therefore a rational target for BC therapy development. This study demonstrated that a graviola fruit extract (GFE) significantly downregulated EGFR gene expression and inhibited the growth of BC cells ...
- DOI:
- 10.1080/01635581.2011.563027
-
http://dx.doi.org/10.1080/01635581.2011.563027
- Author:
- Teas, Jane; Irhimeh, Mohammad R.; Druker, Susan; Hurley, Thomas G.; Hébert, James R.; Savarese, Todd M.; Kurzer, Mindy S.
- Source:
- Nutrition and cancer 2011 v.63 no.5 pp. 743-748
- ISSN:
- 1532-7914
- Subject:
- Alaria; adults; blood serum; body weight; breast neoplasms; clinical trials; fasting; foods; insulin-like growth factor I; isoflavones; macroalgae; nutritional status; postmenopause; protein isolates; risk; women
- Abstract:
- ... Insulin-like growth factor 1 (IGF-1) is an anabolic hormone important for growth and development. However, high-circulating serum concentrations in adults are associated with increased risk of postmenopausal breast cancer. Nutritional status and specific foods influence serum IGF-1 concentrations. Breast cancer incidence is typically low in Asian countries where soy is commonly consumed. Paradoxic ...
- DOI:
- 10.1080/01635581.2011.579383
- PubMed:
- 21711174
- PubMed Central:
- PMC3150209
-
http://dx.doi.org/10.1080/01635581.2011.579383