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- Dahl, Wendy J.; Hung, Wei-Lun; Ford, Amanda L.; Suh, Joon Hyuk; Auger, Jerémié; Nagulesapillai, Varuni; Wang, Yu
- Nutrition research 2020 v.78 pp. 72-81
- bioavailability; blood serum; cardiovascular diseases; carnitine; dementia; excretion; fermentation; food intake; genes; high protein diet; intestinal microorganisms; liquid chromatography; metabolites; prebiotics; probiotics; proteolysis; red meat; ribosomal RNA; risk; sequence analysis; sulfates; tandem mass spectrometry; trimethylamine; women
- ... Diets including red meat and other animal-sourced foods may increase proteolytic fermentation and microbial-generated trimethylamine (TMA) and, subsequently, trimethylamine-N-oxide (TMAO), a metabolite associated with increased risk of cardiovascular disease and dementia. It was hypothesized that compared to usual dietary intake, a maintenance-energy high-protein diet (HPD) would increase products ...