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- Tatucu-Babet, Oana A.; Forsyth, Adrienne; Owen, Emma; Navarro-Perez, Diana; Radcliffe, Jessica; Benheim, Devin; Mendis, Himasha; Jois, Markandeya; Itsiopoulos, Catherine; Tierney, Audrey C.
- Nutrition research 2020 v.78 pp. 82-92
- C-reactive protein; adults; biomarkers; blood serum; body composition; body mass index; enzyme-linked immunosorbent assay; females; intestines; lipopolysaccharides; males; permeability; waist circumference
- ... The association between intestinal permeability (IP) and body composition remains unclear. The gold standard differential sugar-absorption test is arduous to complete, with zonulin being increasingly used as an independent biomarker of IP. This pilot study aimed to explore the association between small IP, zonulin concentrations, and body composition in healthy adults. The urinary lactulose-rhamno ...
- Zhu, Chenghao; Sawrey-Kubicek, Lisa; Bardagjy, Allison S.; Houts, Hannah; Tang, Xinyu; Sacchi, Romina; Randolph, Jody M.; Steinberg, Francene M.; Zivkovic, Angela M.
- Nutrition research 2020 v.78 pp. 36-41
- betaine; blood; breakfast; cardiovascular diseases; carnitine; choline; cross-over studies; eggs; fasting; hypercholesterolemia; intestinal microorganisms; intestines; lipid metabolism; liver; metabolites; overweight; postmenopause; risk; trimethylamine; women
- ... As a crucial part of the symbiotic system, the gut microbiome is metabolically connected to many diseases and conditions, including cardiovascular diseases (CVD). Trimethylamine (TMA) is produced by gut bacteria from dietary choline, betaine, or L-carnitine, and is then converted in the liver to Trimethylamine N-oxide (TMAO), which in turn affects hepatic and intestinal lipid metabolism. Circulati ...