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- Lim, Sun Ha; Kim, Min Ji; Lee, Jongwon
- Nutrition research 2019 v.67 pp. 27-39
- animal models; apoptosis; arabinoxylan; atherosclerosis; autophagy; blood; carotid arteries; clinical trials; cognitive disorders; dementia; hyperlipidemia; neuroglia; psyllium gum; rats; risk factors; risk reduction
- ... Vascular dementia (VaD) develops through a pre-VaD step during which blood vessels narrow due to atherosclerosis attributed to risk factors, including hyperlipidemia. This is followed by a VaD progression step during which inadequate blood supply results in white matter damage and consequent cognitive impairment. Furthermore, administration of arabinoxylan attenuated white matter damage in a rat m ...
- In Kim, Hye; Kim, Jeon-Kyung; Kim, Jae-Young; Jang, Se-Eun; Han, Myung Joo; Kim, Dong-Hyun
- Nutrition research 2019 v.67 pp. 78-89
- AMP-activated protein kinase; Bifidobacterium longum; Lactobacillus plantarum; Proteobacteria; alanine transaminase; anti-inflammatory activity; aspartate transaminase; blood; cholesterol; colitis; colon; endotoxemia; fatty liver; high fat diet; human cell lines; inflammation; intestinal microorganisms; lipopolysaccharides; liver; membrane permeability; mice; obesity; occludins; oral administration; probiotics; transcription factor NF-kappa B; triacylglycerols
- ... Long-term feeding of a high-fat diet (HFD) induces endotoxemia and gastrointestinal inflammation by disturbing gut microbiota composition and membrane permeability, resulting in the acceleration of obesity. Some probiotics exhibit anti-inflammatory effects in vitro and in vivo. Therefore, we hypothesized that anti-inflammatory probiotics could lead to the simultaneous attenuation of endotoxemia, l ...