An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
cross-sectional studies; diet recall; malnutrition; nutrition research; nutritional status; protein intake; quality of life; regression analysis; risk; sarcopenia; skeletal muscle
Abstract:
... Sarcopenia, which is characterized by an age-related decline in skeletal muscle mass, strength, and function, is an important geriatric syndrome that is closely related to the nutritional status and quality of life (QoL) of older adults. The aim of this study was to compare the nutritional status and QoL of nursing home residents according to sarcopenia. We hypothesized that a daily protein intake ...
... Severe acute malnutrition (SAM), due to poor energy and/or protein intake, is associated with poor growth, depressed immune function, and long-term impacts on metabolic function. As the liver is a major metabolic organ and malnutrition poses metabolic stress, we hypothesize that SAM will be associated with alterations in the hepatic metabolome reflective of oxidative stress, gluconeogenesis, and k ...
C-reactive protein; National Health and Nutrition Examination Survey; body mass index; cross-sectional studies; hand strength; mental depression; nutrition research; odds ratio; protein intake; quality of life; questionnaires; sarcopenia; weight control; weight loss; Korean Peninsula
Abstract:
... The hypothesis of this study is that weight-related behaviors such as weight perception and weight control efforts may be related to health indicators such as grip strength as an indicator of muscle strength. This cross-sectional study aimed to prove this hypothesis by assessment of the associations of perceived weight status, weight misperceptions, and weight control efforts with grip strength. A ...
... Blood pressure (BP) responses to exercise yield prognostic information beyond resting BP. While habitual higher dietary protein intake is associated with reduced resting BP, few studies have assessed the impact of high-protein meals on acute BP and vasoactive biomarker responses to exercise. To test the hypothesis that consuming a higher-protein, lower fat meal (HP; 30 g protein, 17 g fat, 52 g ca ...
creatinine; excretion; men; protein intake; standard deviation; t-test; urea nitrogen; urine; women; Japan
Abstract:
... In this study, we hypothesized that spot urine can be used to predict protein intake at both group and individual levels. Participants (n = 369) of this study were recruited from all 47 prefectures in Japan. Sex-specific formulas were developed based on the ratio of urea nitrogen to creatinine concentration obtained from 3 spot urine samples. Validity of the formulas was examined against two 24-ho ...
body weight; calorimetry; energy intake; food records; malnutrition; metabolism; nutrition research; protein intake; sarcopenia; Australia; Netherlands
Abstract:
... To individualize nutritional interventions for the prevention and treatment of malnutrition and sarcopenia, it is required to understand the nutritional needs of older adults. This study explores the nutritional needs of geriatric outpatients. We hypothesized that inadequate energy and protein intake is common in geriatric outpatients. Data were retrieved from 2 cohort studies encompassing communi ...
Japanese people; actigraphy; adolescents; copper; cross-sectional studies; dietary minerals; eating habits; elderly; energy intake; food frequency questionnaires; food intake; food quality; health status; iron; lifestyle; magnesium; mental health; physical activity; potassium; protein intake; riboflavin; sleep; tryptophan; vitamin K; women; zinc
Abstract:
... Literature reports suggest that subjective sleep quality is associated with nutrient intake in elderly people and workers. However, few studies have suggested an association between objective sleep quality and dietary intake in adolescents and young women. We hypothesized that objective sleep quality is associated with dietary intake in adolescents and young women. We evaluated the association bet ...
amino acids; antioxidant activity; bone health; bone resorption; calcium; dietary protein; glucose; glycemic index; microgravity; models; muscle tissues; muscles; nutritional intervention; protein intake; proteins; risk; space flight; vitamin D; vitamin K
Abstract:
... Bed rest is necessary for many medical conditions but also used as a ground-based model for space flight (along with head-down tilt to simulate fluid shifts in microgravity). The purpose of this review is to examine nutritional interventions during bed rest and spaceflight for prevention of muscle and strength loss, glucose intolerance, bone resorption, and cardiovascular problems. Increased dieta ...
Internet; National Institutes of Health; adults; alcohol drinking; body mass index; carbohydrate intake; energy intake; fat intake; females; food frequency questionnaires; food intake; males; microbiome; observational studies; protein intake
Abstract:
... Minimal recent research explores how alcohol use disorder (AUD) affects dietary intake during periods of alcohol consumption. Therefore, we aimed to assess the feasibility and utility of a computerized food frequency questionnaire, the Diet History Questionnaire II (DHQ II), to quantify dietary intake in adults with AUD. Participants were adult men and women seeking treatment for AUD at the Nation ...
AMP-activated protein kinase; amino acids; autophagy; dietary protein; eating habits; energy; exercise; fibroblast growth factors; glycolysis; immune response; immunosuppression; inflammation; insulin; mitochondria; muscle protein; obesity; protein intake; protein synthesis; quality of life; rapamycin; risk reduction; skeletal muscle; transcription (genetics)
Abstract:
... Exercise is considered to be the best approach to improve quality of life, and together with a healthy and adequate dietary pattern, exercise represents the best strategy to reduce the risk of chronic metabolic and inflammatory diseases, such as those related to obesity. The regularity and intensity of exercise is modulated at the molecular level in the skeletal muscle by two protein kinases, the ...
Paula Bresciani Leite; Ana Raimunda Dâmaso; Vanessa Schoenardie Poli; Ricardo Badan Sanches; Stephan Garcia Andrade Silva; João Pedro Novo Fidalgo; Maythe Amaral Nascimento; Camila Aparecida Machado de Oliveira; Danielle Arisa Caranti
adults; binge eating disorder; binging; blood glucose; body composition; body mass index; carbohydrates; comorbidity; diastolic blood pressure; high density lipoprotein; metabolic syndrome; obesity; protein intake; risk factors; sodium; systolic blood pressure; therapeutics; triacylglycerols; waist circumference
Abstract:
... Obesity-associated comorbidities greatly impact the quality and expectancy of life. Binge eating disorder (BED) is the most prevalent eating disorder and it is an important risk factor for obesity and metabolic syndrome (MetS). For these reasons, we aimed to assess the effect of an interdisciplinary therapy on the symptoms of BED and the prevalence of MetS in obese adults. It was hypothesized that ...
cell transplantation; diet; energy intake; globulins; leukemia; muscle protein; muscle strength; muscles; patients; protein energy malnutrition; protein intake; protein synthesis; serum albumin; skeletal muscle; stem cells
Abstract:
... Severe protein-energy malnutrition (PEM) and skeletal muscle wasting are commonly observed in patients with acute leukemia. Recently, the ingestion of a soy-whey protein blend has been shown to promote muscle protein synthesis (MPS). Thus, we tested the hypothesis that the ingestion of a soy-whey blended protein (BP) may improve the PEM status and muscle mass in acute leukemia patients. In total, ...
food intake; malnutrition; albumins; energy intake; fractional synthesis rate; males; chronic diseases; casein; low protein diet; protein intake; oxidation; rats
Abstract:
... The reduced/oxidized state of plasma albumin is influenced by many factors, including chronic diseases and strenuous training. Recently, the reduced/oxidized state has also been shown to be associated with dietary protein and energy intakes in rats. We hypothesized that dietary protein intake may modulate the reduced/oxidized state of plasma albumin by altering the rate of albumin synthesis and th ...
adults; blood lipids; body composition; body mass index; dairy protein; dieting; energy; high density lipoprotein cholesterol; immune response; low density lipoprotein cholesterol; monocytes; obesity; protein intake; protein isolates; triacylglycerols; weight loss
Abstract:
... Monocytes are involved in immune responses, and specific monocyte subpopulations (MS) that express intermediate to high levels of CD16 are associated with obesity and cardiovascular events. Consuming high protein (HP) when dieting improves body composition and cardiometabolic health outcomes, but whether HP affects MS during weight loss remains unknown. We assessed the effect of HP on energy restr ...
alanine; amino acid composition; body mass index; children; choline; cysteine; cystic fibrosis; dietary protein; energy; glycine (amino acid); histidine; homocysteine; lean body mass; lipid content; lipids; metabolism; methionine; placebos; protein intake; threonine; valine
Abstract:
... The present study determined the plasma amino acid status in children with cystic fibrosis (CF) and pancreatic insufficiency (PI) in the modern medical and nutritional care setting and investigated the effect of choline supplementation on amino acid status. A total of 110 children aged 5 to 18 years with CF and PI were randomized to receive choline-enriched structured lipid (LYM-X-SORB) or placebo ...
... Maternal nutritional stress during pregnancy acts to program offspring metabolism. We hypothesized that the nutritional stress caused by maternal fructose or low protein intake during pregnancy would program the offspring to develop metabolic aberrations that would be exacerbated by a diet rich in fructose or fat during adult life. The objective of this study was to characterize and compare the fe ...
consciousness; correlation; dietitians; females; food frequency questionnaires; nutrients; nutrition assessment; nutrition knowledge; potassium; protein intake; sodium; urine; Japan
Abstract:
... To investigate the hypothesis that misreporting observed in dietary assessments would be associated with nutrition knowledge and health consciousness, we compared the degree of misreporting between 99 female dietitians and 117 nondietitians who worked at welfare facilities in Japan. Sodium, potassium, and protein intake were assessed by two 24-hour urine collections, 4-day semiweighed dietary reco ...
... Whey protein (WP) is known for its nutritional value and antioxidant properties. The aim of this study was to evaluate whether the antioxidant properties of WP could contribute to muscle weight gain in response to resistance exercise (RE). We hypothesized that WP ingestion could increase muscle weight gain in rats subjected to an RE program, through inhibition of oxidative effects induced by high- ...
Lenka Dušátková; Hana Zamrazilová; Irena Aldhoon-Hainerová; Barbora Sedláčková; Josef Včelák; Petr Hlavatý; Běla Bendlová; Marie Kunešová; Vojtěch Hainer
adiposity; adolescents; alleles; body mass index; calcium; carbohydrates; energy intake; food intake; homeostasis; hypothalamus; obesity; protein intake; risk; waist circumference
Abstract:
... Specific targets for most obesity candidate genes discovered by genomewide association studies remain unknown. Such genes are often highly expressed in the hypothalamus, indicating their role in energy homeostasis. We aimed to evaluate the associations of selected gene variants with adiposity and dietary traits. Anthropometric parameters, fat mass, dietary intake (total energy, fat, protein, carbo ...
National Health and Nutrition Examination Survey; ascorbic acid; body composition; body mass index; calcium; elderly; females; high density lipoprotein; homeostasis; insulin; insulin resistance; males; men; models; muscles; nutrients; nutritional intervention; nutritional status; obesity; protein intake; sarcopenia; skeletal muscle; triacylglycerols; vitamin D; women; young adults; Korean Peninsula
Abstract:
... In this study, we examined the relationship between sarcopenic obesity (SO) and nutrition status, according to sex in Korean adults who were 60 years or older. Body composition was categorized as SO, sarcopenic nonobesity, nonsarcopenic obesity, and nonsarcopenic nonobesity. Obesity was defined by body mass index. Sarcopenia was defined as an appendicular skeletal muscle mass divided by weight (Wt ...
... The aim of this study was to investigate the association between dietary protein (PRO) intake and maximal and rapid strength of the leg flexors in blue collar (BC) working men. Twenty-four young (age, 23.2 ± 2.1 years) and 19 older (age, 52.8 ± 5.2 years) men employed in BC occupations completed a 3-day dietary record and isometric strength testing of the leg flexors. Food logs were analyzed for t ...
Canadians; Dietary Reference Intakes; body mass index; correlation; dairy products; dietary protein; fetal development; food frequency questionnaires; infants; low birth weight; pregnancy outcome; pregnant women; protein intake; protein sources; weight gain; British Columbia
Abstract:
... Adequate dietary protein intake throughout pregnancy is essential to ensure healthy fetal development. Insufficient and excessive maternal dietary protein intakes are both associated with intrauterine growth restriction, resulting in low birth weight infants. The aim of this study was to analyze the dietary protein intake patterns of healthy pregnant women in Vancouver, British Columbia, during ea ...
adults; correlation; diabetes mellitus; eating habits; energy intake; food frequency questionnaires; food records; nutrients; nutrition assessment; patients; protein intake; risk; saturated fats; volunteers
Abstract:
... Food frequency questionnaires (FFQs) provide an inexpensive tool for dietary assessment. Given the scarcity of data on their validity for nutritional analysis in persons with overt diabetes mellitus or with increased risk of diabetes (relatives of patients with diabetes), this study tests the hypothesis that an FFQ, adapted to local dietary habits, yields a reliable estimate of nutrient intake whe ...
body weight; dietary protein; dual-energy X-ray absorptiometry; elderly; energy intake; food records; lean body mass; physical activity; protein intake
Abstract:
... Lean body mass (LBM) is important to maintain physical function during aging. We hypothesized that dietary protein intake and leisure-time physical activity are associated with LBM in community-dwelling older adults. To test the hypothesis, participants (n = 237; age, 65-92 years) did 3-day weighed food records and reported physical activity. Body composition was assessed using dual-energy x-ray a ...
... The mainstream of phenylketonuria (PKU) management is lifelong restriction of protein intake; however, this dietary restriction may be accompanied by insufficient dietary intake of long-chain polyunsaturated fatty acids (LCPUFA). The objective of this review was to assess whether significant depletion of LCPUFA can be detected in PKU patients on low-protein diet and whether LCPUFA supplementation ...
HIV infections; anemia; children; cognition; confidence interval; equations; growth performance; hemoglobin; odds ratio; prospective studies; protein intake; South Africa
Abstract:
... Anemia is a common complication of pediatric HIV infection and is associated with suboptimal cognitive performance and growth failure. Routine iron supplementation is not provided to South African HIV-infected children. We hypothesized that dietary iron intake without supplementation is sufficient to protect against iron deficiency (ID) in HIV-infected children receiving highly active antiretrovir ...
adults; body measurements; bone density; lean body mass; legs; low calorie diet; men; overweight; protein intake; proteins; weight loss; women
Abstract:
... Secondary analyses of data from 2 studies were used to assess the effects of protein intake and sex on diet-induced changes in body composition. The primary hypothesis was that the changes of body composition via energy restriction (ie, lean body mass [LBM], fat mass [FM], and bone) would be sex and diet specific. For 12 weeks, 43 male (study 1) and 45 female (study 2) overweight and obese adults ...
blood glucose; body mass index; elderly; glucose; glucose tolerance; lean body mass; muscle strength; parathyroid hormone; protein intake; strength training; vitamin D
Abstract:
... We assessed the influence of serum 25-hydroxyvitamin D (25[OH]D) and parathyroid hormone (PTH) concentrations on oral glucose tolerance, body composition, and muscle strength in older, nondiabetic adults who performed resistance exercise training (RT) while consuming diets with either 0.9 or 1.2 g protein kg⁻¹ d⁻¹. We hypothesized that individuals with insufficient 25(OH)D and/or high PTH would ha ...
adults; blood glucose; body mass index; diastolic blood pressure; dietary protein; food frequency questionnaires; glucose; high density lipoprotein; linear models; men; protein content; protein intake; risk factors; triacylglycerols; waist circumference; women
Abstract:
... In this study, we investigated the hypothesis that dietary protein content and type are related to cardiometabolic risk factors including body mass index, waist circumference (WC), serum triglycerides, high-density lipoprotein cholesterol (HDL-C), serum fasting glucose, and blood pressure. This population-based study was conducted on 2537 subjects aged 19 to 70 years and selected from among partic ...
correlation; diet history; dietary protein; energy intake; energy requirements; excretion; nutrient density; nutrients; potassium; protein intake; proteins; questionnaires; sodium; women
Abstract:
... It is unclear whether misreporting of nutrient intakes differs according to energy reporting status. We examined misreporting of dietary protein, potassium, and sodium in under-, acceptable, and over-reporters of energy intake. Our hypothesis was that degree of misreporting of these three nutrients differs among under-, acceptable, and over-reporters. Participants were 1043 Japanese women aged 18 ...
Dietary Reference Intakes; Estimated Average Requirement; World Health Organization; anemia; calcium; child growth; diet recall; energy; foods; growth retardation; hematologic tests; hemoglobin; iron; lipids; malnutrition; preschool children; protein intake; underweight; vitamin A; wasting syndrome; zinc; China
Abstract:
... This study documented the relationships among dietary intake, growth failure, and anemia in a convenience sample of 172 children aged 1 to 5 years in rural Yunnan Province, China. We hypothesized that most children would have suboptimal intakes of key nutrients associated with child growth and anemia and that undernutrition would be more common in children with poor growth and in those who were an ...
African Americans; adiposity; body mass index; calcium; carbohydrates; correlation; cross-sectional studies; dual-energy X-ray absorptiometry; lipids; obesity; protein intake; vitamin D; women
Abstract:
... Calcium and vitamin D are associated with obesity. We hypothesized that African American women with higher calcium and vitamin D intakes would have lower body fat compared with women with lower calcium and vitamin D intakes. This cross-sectional study included 100 premenopausal African American women aged 18 to 40 years with a spectrum of body mass indices (17.3-46.7 kg/m²). Dietary information wa ...
... We hypothesized that soy protein (S)–based diets fed during pregnancy and lactation increase food intake and the presence of characteristics of the metabolic syndrome to a lesser extent in female than in male rats. Soy protein– and casein (C)-based American Institute of Nutrition–93G diets were fed to 2 groups (n = 12 per group) of pregnant Wistar rats from day 3 of gestation and throughout lactat ...
adults; body composition; dual-energy X-ray absorptiometry; food intake; lipids; protein intake; protein sources; renin-angiotensin system; resting energy expenditure; satiety; systolic blood pressure; weight loss; whey; whey protein
Abstract:
... We hypothesized that a whey protein diet would result in greater weight loss and improved body composition compared with standard weight loss diets. Weight change, body composition, and renin-angiotensin aldosterone system activity in midlife adults were compared between diet groups. Eighteen subjects enrolled in a 5-month study of 8-week controlled food intake followed by 12-weeks ad libitum inta ...
food intake; Japanese people; pasta; energy intake; Chinese people; gender; human resources; data collection; nutritional adequacy; automation; cafeterias; lunch; principal component analysis; data analysis; protein intake; food choices; computer software; food records
Abstract:
... The Smart-card-based Automatic Meal Record system for company cafeterias (AutoMealRecord system) was recently developed and used to monitor employee eating habits. The system could be a unique nutrition assessment tool for automatically monitoring the meal purchases of all employees, although it only focuses on company cafeterias and has never been validated. Before starting an interventional stud ...
... Dietary proteins can influence colonic carcinogenesis; some proteins have a promotional effect, whereas others exhibit a preventive effect. Dietary egg yolk proteins have been reported to suppress the expression of colon tumors in rats. In this study, we investigated the effect of consumption egg yolk proteins on cell proliferation in a rat model of azoxymethane (AOM)-induced colon cancer. We hypo ...
... The molecular mechanisms responsible for alterations in lysine α-ketoglutarate reductase (LKR) activity are unknown. Therefore, the aim of these studies was to discern the mechanism(s) responsible for induction of hepatic LKR activity in rodents fed excess dietary protein. Four studies were conducted that used 84 mice. Mice were fed either a high-protein (50% casein) or adequate-protein (20% casei ...
sociodemographic characteristics; dietary protein; eating habits; African Americans; arginine; protein deficiencies; lifestyle; risk factors; inflammation; young adults; smoking (habit); essential amino acids; protein intake; portal hypertension; National Health and Nutrition Examination Survey; Hispanic Americans; oxidative stress
Abstract:
... Little is known regarding the patterns of dietary intake of the amino acid l-arginine in the general population and, particularly, whether intake varies according to race or the presence of cardiovascular risk factors. This study is an analysis of adults 18 years and older who participated in the Third National Health and Nutrition Examination Survey, a national public-use nutrition survey of noni ...
whey protein; digestible protein; elderly; nitrogen balance; muscle contraction; muscle protein; protein supplements; free amino acids; nutrient availability; essential amino acids; contractile proteins; elderly nutrition; protein intake; clinical nutrition; phenylalanine; amino acid metabolism; protein deposition; lean body mass
Abstract:
... It is recognized that both whey protein (WY) and essential amino acids (EAA) are stimuli for muscle protein anabolism. The aim of the present study was to determine if the effects of WY ingestion on muscle protein accrual in elderly persons are due solely to its constituent EAA content. Fifteen elderly persons were randomly assigned to ingest a bolus of either 15 g of WY, 6.72 g of EAA, or 7.57 g ...
dietary protein; nutritional status; copper; nutrient deficiencies; hemoglobin; dietary nutrient sources; beef; animal models; protein intake; ferrous sulfate; rats; iron deficiency anemia; heme iron
Abstract:
... This experiment was designed to determine whether dietary hemoglobin (Hgb) iron (Fe) could sustain normal Fe status in growing rats adequate or deficient in copper (Cu). Forty-eight weanling rats were divided into 3 groups, each consisting of 16 animals. One group was fed a diet containing 40 mg Fe/kg as ferrous sulfate (FeSO4). A second and a third group were fed 40 and 70 mg Fe/kg, respectively, ...
high protein diet; casein; casein hydrolysates; glycemic effect; glycemic control; rats; animal models; protein intake; glucose tolerance; insulin secretion; glucagon; hypoglycemia
Abstract:
... The aim of this study was to explore, in normal rats, the effects upon selected metabolic and hormonal variables of both the rapid intake or long-term administration of a diet containing 13% protein (wt/wt; control diet) and enriched with 40% (wt/wt) casein. The response to the intake of the control and casein diet was examined in meal-trained rats given access to these diets for 15 minutes. A glu ...
WIC Program; rural areas; infant feeding; breast feeding; infants; dietary protein; protein intake; dietary minerals; phosphorus; vitamin E; blood serum; lead; heme iron; iron deficiency anemia; maternal nutrition
Abstract:
... The objectives were to document blood lead levels (BLLs) in a group of rural infants aged 5 to 26 months, measure the relationship between BLL and iron status, and identify nutrients associated with BLL. Dietary intake was measured using 2 multiple-pass 24-hour intakes of 57 infants who participated in the WIC program. The mean BLL was 30 ± 16 μg/L. Twelve infants, all older than 12 months, were i ...
... The well-fed free-living adult subjects in this study show evidence of skeletal muscle loss, evaluated from the increased levels of plasma alanine (p < 0.0001) and decreased urinary levels of isoleucine, leucine, lysine, glycine and alanine (all p values <0.005). Plasma fatty acid analysis showed low percentages of cis-linoleic acid associated with high percentages of both trans-linoleic acid and ...
body fat; body mass index; calcium; cholesterol; eating habits; energy intake; fat intake; food frequency questionnaires; iodine; minerals; protein intake; saturated fatty acids; school children; selenium; vitamin D; Croatia
Abstract:
... The aim of this study was to assess the quality of children's daily diet and some nutritional habits with regard to fat, cholesterol and saturated fatty acid (SFA) intake. Food Frequency Questionnaire (FFQ) with weight, height, Body Mass Index (BMI) and body fat as anthropometric parameter was used in children aged 7-10 years. The average energy intake in almost all subgroups was below the Recomme ...
breast feeding; carbohydrates; children; eating habits; fat intake; food industry; food intake; obesity; parents; protein intake; television; weaning
Abstract:
... The increased prevalence of obesity highlights the need of programs for its prevention. In the obesity prevention programs calorie and nutrient intake, emotional and social cues related to food intake must be considered. Thus, in order to prevent development of obesity modifying the nutritional factors it would be necessary: increasing breast-feeding in terms of percentage and duration; modifying ...