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- Dary, Omar
- Nutrition reviews 2009 v.67 no.4 pp. 235-244
- humans; folic acid; nutrient requirements; nutrient excess; nutrient deficiencies; food fortification; nutritional intervention; risk assessment; adverse effects; blood chemistry; homocysteine; deficiency diseases; metabolism; Tolerable Upper Intake Level
- ... Folate is an essential micronutrient, and its nutritional inadequacy is widespread; hence, programs to increase its intake are necessary. However, many concerns about possible adverse effects due to excesses have been raised. Serum folate levels are directly correlated with intake and, when low, are associated with neural tube defects (NTD), high blood homocysteine levels, and megaloblastic anemia ...