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1. Development of a recombinase polymerase amplification (RPA) fluorescence assay for the detection of Schistosoma haematobium

Author:
Rostron, Penelope; Pennance, Tom; Bakar, Faki; Rollinson, David; Knopp, Stefanie; Allan, Fiona; Kabole, Fatma; Ali, Said M.; Ame, Shaali M.; Webster, Bonnie L.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 514
ISSN:
1756-3305
Subject:
Zanzibar,   etc   ; DNA; Schistosoma haematobium; batteries; diagnostic techniques; eggs; fluorescence; genomics; monitoring; pathogens; patients; scanners; schistosomiasis haematobia; school children; urine;     Show all 15 Subjects
Abstract:
... BACKGROUND: Accurate diagnosis of urogenital schistosomiasis is vital for surveillance and control programmes. While a number of diagnostic techniques are available there is a need for simple, rapid and highly sensitive point-of-need (PON) tests in areas where infection prevalence and intensity are low. Recombinase Polymerase Amplification (RPA) is a sensitive isothermal molecular diagnostic techn ...
DOI:
10.1186/s13071-019-3755-6
PubMed:
31685024
PubMed Central:
PMC6827214