Ulrich, Michael, et al. ; Kryda, Kristina; Six, Robert H.; Walsh, Kelly F.; Holzmer, Susan J.; Chapin, Sara; Mahabir, Sean P.; Myers, Melanie; Inskeep, Tammy; Rugg, Jady; Cundiff, Blair; Pullins, Aleah; McCall, John W.; McTier, Tom L.; Maeder, Steven J.; Show all 15 Authors
Dirofilaria immitis; adults; antigens; dirofilariasis; dog diseases; dogs; heartworms; ivermectin; larvae; moxidectin; necropsy; oral administration; pyrantel; valleys; veterinary clinics; United States
... BACKGROUND: Dirofilaria immitis is a filarial parasite of dogs that can cause serious or fatal cardiopulmonary disease. Three studies were conducted to evaluate the efficacy and safety of monthly treatment with moxidectin in a chewable tablet product in combination with sarolaner and pyrantel to prevent heartworm disease in dogs after experimental challenge and in a clinical field study in the USA ...