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1. Risk factors for lymphatic filariasis in two villages of the Democratic Republic of the Congo

Author:
Boussinesq, Michel,   et al.   ; Chesnais, Cédric B.; Awaca-Uvon, Naomi-Pitchouna; Vlaminck, Johnny; Tambwe, Jean-Paul; Weil, Gary J.; Pion, Sébastien D.;     Show all 7 Authors
Source:
Parasites & vectors 2019 v.12 no.1 pp. 162
ISSN:
1756-3305
Subject:
Bancroftian filariasis; Culicidae; Wuchereria bancrofti; bed nets; blood; drugs; epidemiology; farmers; levamisole; males; population density; regression analysis; risk factors; risk reduction; rivers; villages; Democratic Republic of the Congo
Abstract:
... BACKGROUND: Little is known regarding risk factors for lymphatic filariasis (LF) in Central Africa. To expand on what is known, we studied the epidemiology of LF in two endemic villages in the Democratic Republic of the Congo. METHODS: Dependent variables were Wuchereria bancrofti antigenaemia detected with filarial test strips (FTS) and microfilaraemia detected by night blood smears. The followin ...
DOI:
10.1186/s13071-019-3428-5

2. Impact of 19 years of mass drug administration with ivermectin on epilepsy burden in a hyperendemic onchocerciasis area in Cameroon

Author:
Boussinesq, Michel,   et al.   ; Boullé, Charlotte; Njamnshi, Alfred K.; Dema, Fidèle; Mengnjo, Michel K.; Siewe Fodjo, Joseph Nelson; Bissek, Anne-Cécile Zoung-Kanyi; Suykerbuyk, Patrick; Lenou-Nanga, Cédric G.; Nana-Djeunga, Hugues C.; Kamgno, Joseph; Chesnais, Cédric B.; Colebunders, Robert;     Show all 13 Authors
Source:
Parasites & vectors 2019 v.12 no.1 pp. 114
ISSN:
1756-3305
Subject:
Onchocerca volvulus; drugs; endemic diseases; epilepsy; household surveys; households; ivermectin; microfilariae; onchocerciasis; questionnaires; screening; villages; Cameroon
Abstract:
... BACKGROUND: Surveys conducted in 1991–1992 in the Mbam Valley (Cameroon) revealed that onchocerciasis was highly endemic, with community microfilarial loads (CMFL) > 100 microfilariae/snip in some villages. Also in 1991–1992, a survey of suspected cases of epilepsy (SCE) found 746 SCE using a questionnaire administered to individuals identified by key informants, with prevalences reaching 13.6% in ...
DOI:
10.1186/s13071-019-3345-7

3. Still mesoendemic onchocerciasis in two Cameroonian community-directed treatment with ivermectin projects despite more than 15 years of mass treatment

Author:
Boussinesq, Michel,   et al.   ; Kamga, Guy-Roger; Dissak-Delon, Fanny N.; Nana-Djeunga, Hugues C.; Biholong, Benjamin D.; Mbigha-Ghogomu, Stephen; Souopgui, Jacob; Zoure, Honorat G. M.; Kamgno, Joseph; Robert, Annie;     Show all 10 Authors
Source:
Parasites & vectors 2016 v.9 no.1 pp. 581
ISSN:
1756-3305
Subject:
compliance; cross-sectional studies; gender; indigenous species; ivermectin; littoral zone; microfilariae; onchocerciasis; statistical analysis; Cameroon
Abstract:
... BACKGROUND: After more than a decade of community-directed treatment with ivermectin (CDTI) in Centre and Littoral Regions of Cameroon, onchocerciasis endemicity was still high in some communities according to the 2011 epidemiological evaluations. Some corrective measures were undertaken to improve the CDTI process and therefore reduce the burden of the disease. The objective of the present study ...
DOI:
10.1186/s13071-016-1868-8
PubMed:
27842567
PubMed Central:
PMC5109673

4. Impact of repeated ivermectin treatments against onchocerciasis on the transmission of loiasis: an entomologic evaluation in central Cameroon

Author:
Boussinesq, Michel,   et al.   ; Kouam, Marc K; Tchatchueng-Mbougua, Jules B; Demanou, Maurice; Pion, Sébastien DS; Kamgno, Joseph;     Show all 6 Authors
Source:
Parasites & vectors 2013 v.6 no.1 pp. 283
ISSN:
1756-3305
Subject:
Chrysops silacea; Loa loa; head; ivermectin; larvae; onchocerciasis; people; risk; Cameroon
Abstract:
... BACKGROUND: Annual community-directed treatment with ivermectin (CDTI) have been carried out since 1999 in the Lekie division (central region of Cameroon where most cases of Loa-related post ivermectin severe adverse events were reported) as part of the joined activities of the African Programme for Onchocerciasis Control (APOC) and Mectizan® Donation Program (MDP). As large-scale administration o ...
DOI:
10.1186/1756-3305-6-283
PubMed:
24289520
PubMed Central:
PMC3849770

5. A case study of risk factors for lymphatic filariasis in the Republic of Congo

Author:
Boussinesq, Michel,   et al.   ; Chesnais, Cédric B; Missamou, François; Pion, Sébastien D; Bopda, Jean; Louya, Frédéric; Majewski, Andrew C; Fischer, Peter U; Weil, Gary J;     Show all 9 Authors
Source:
Parasites & vectors 2014 v.7 no.1 pp. 300
ISSN:
1756-3305
Subject:
Culicidae; Wuchereria bancrofti; anthelmintics; bed nets; blood; case studies; children; correlation; epidemiology; females; filariasis; fish; males; men; multivariate analysis; protective effect; regression analysis; risk; risk factors; women; Republic of the Congo
Abstract:
... BACKGROUND: Little is known regarding risk factors for lymphatic filariasis (LF) in Central Africa. We studied the epidemiology of LF in an endemic village in the Republic of Congo. METHODS: Dependent variables were Wuchereria bancrofti antigenemia (ICT card test) and microfilaremia (night blood smears). The following factors were investigated: sex, age, bed net, latrines, source of water, uptake ...
DOI:
10.1186/1756-3305-7-300
PubMed:
24984769
PubMed Central:
PMC4089930