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- Wiszniewsky, Anna; Ritter, Manuel; Krupp, Vanessa; Schulz, Sandy; Arndts, Kathrin; Weighardt, Heike; Wanji, Samuel; Hoerauf, Achim; Layland, Laura E.
- Parasitology research 2019 v.118 no.2 pp. 539-549
- thoracic cavity, etc ; Bancroftian filariasis; Brugia malayi; CD8-positive T-lymphocytes; Litomosoides sigmodontis; Wuchereria bancrofti; cytokines; eosinophils; immune response; in vitro studies; macrophages; male genitalia; mice; Show all 13 Subjects
- ... Worldwide approximately 68 million people are infected with lymphatic filariasis (Lf), provoked by Wuchereria bancrofti, Brugia malayi and Brugia timori. This disease can lead to massive swelling of the limbs (elephantiasis) and disfigurement of the male genitalia (hydrocele). Filarial induced immune regulation is characterised by dominant type 2 helper T cell and regulatory immune responses. In v ...