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- Kshirsagar, Nilima A.; Gogtay, N. J.; Garg, B. S.; Deshmukh, P. R.; Rajgor, D. D.; Kadam, V. S.; Thakur, P. A.; Gupta, A.; Ingole, N. S.; Lazdins-Helds, J. K.
- Parasitology research 2017 v.116 no.10 pp. 2683-2694
- filariasis, etc ; adults; albendazole; antigens; children; diethylcarbamazine; drugs; morbidity; socioeconomic development; India; Show all 10 Subjects
- ... Lymphatic filariasis (LF) affects 73 countries, causes morbidity and impedes socioeconomic development. We had found no difference in safety and micro (Mf) and macro filarial action of single-dose diethylcarbamazine (DEC) and DEC + albendazole (ABZ) in an F01 study done in India (year 2000). There was a programmatic need to evaluate safety and efficacy of multiple annual treatments (F02). Subjects ...
- Chauhan, Nikhil; Banerjee, Priyankana; Khatri, Vishal K.; Canciamille, Andrew; Gilles, Jessica; Kalyanasundaram, Ramaswamy
- Parasitology research 2017 v.116 no.10 pp. 2821-2830
- filariasis, etc ; Macaca mulatta; T-lymphocytes; adjuvants; adults; alum; animal models; antigens; chitosan; immune response; immunization; interferon-gamma; interleukin-17; interleukin-4; patients; rodents; vaccines; vector control; Show all 18 Subjects
- ... Mass drug administration (MDA) is the current strategy for interrupting the transmission of lymphatic filariasis (LF) infection and control of the disease in endemic areas. However, subject non-compliance has resulted in the presence of several “transmission hotspots” in the endemic regions threatening the reemergence of LF. This situation is further complicated by the fact that the drugs used in ...
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