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- Tan, Chung-Wei; Jesudhasan, Palmy; Woo, Patrick T. K.
- Parasitology research 2008 v.102 no.2 pp. 265-275
- Cryptobia, etc ; Oncorhynchus mykiss; Salmo salar; blood; cysteine proteinases; fish; genes; hematocrit; metalloproteinases; parasitemia; pathogens; plasmid vectors; plasmids; recombinant vaccines; Show all 14 Subjects
- ... Cysteine protease is a metabolic enzyme, whereas metalloprotease is the virulent factor in cryptobiosis caused by Cryptobia salmositica. Recombinant DNA vaccines were produced with the insertion of either the metalloprotease or cysteine protease gene of C. salmositica into plasmid vectors (pEGFP-N). As expected, fishes (Oncorhynchus mykiss and Salmo salar) injected intramuscularly with the metallo ...