U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Journal name Pesticide biochemistry and physiology Remove constraint Journal name: Pesticide biochemistry and physiology Publication year rev 7987-2013 Remove constraint Publication year rev: 7987-2013 Source 2013 v.106 no.3 Remove constraint Source: 2013 v.106 no.3
Start Over

Search

15  Search Results

1 - 15 of 15
Number of results to display per page

Search Results

1. Diamide insecticides: Global efforts to address insect resistance stewardship challenges

Author:
Luís A. Teixeira; John T. Andaloro
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 76-78
ISSN:
0048-3575
Subject:
biochemistry; business enterprises; evolution; flubendiamide; growers; insecticide resistance; insecticides; insects; pests; physiology; resistance management; risk; trademarks
Abstract:
... The diamides are the most recent addition to the limited number of insecticide classes with specific target site activity that are highly efficacious, control a wide pest spectrum, and have a favorable toxicological profile. Currently available diamide insecticides include chlorantraniliprole and flubendiamide, with cyantraniliprole already being sold in some countries as launch progresses. Fluben ...
DOI:
10.1016/j.pestbp.2013.01.010

2. Evaluation of novel carbamate insecticides for neurotoxicity to non-target species

Author:
Ying Jiang; Daniel Swale; Paul R. Carlier; Joshua A. Hartsel; Ming Ma; Fredrik Ekström; Jeffrey R. Bloomquist
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 156-161
ISSN:
0048-3575
Subject:
Anopheles gambiae; Daphnia magna; acetylcholinesterase; bendiocarb; bioassays; birds; carbofuran; disease prevalence; inhibitory concentration 50; insecticides; malaria; mammals; neurotoxicity; nontarget organisms; physiology; propoxur; vector control
Abstract:
... Malaria is an urgent world health concern and vector control is one important option for reducing disease prevalence. Increased reports of pyrethroid-resistant mosquito strains have amplified the need for new vector-control chemicals. We compared three commercially available carbamate insecticides (carbofuran, bendiocarb, and propoxur) to eight experimental compounds 1–8 for activity against Anoph ...
DOI:
10.1016/j.pestbp.2013.03.006

3. Human lice: Past, present and future control

Author:
J. Marshall Clark; K.S. Yoon; S.H. Lee; B.R. Pittendrigh
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 162-171
ISSN:
0048-3575
Subject:
Pediculus humanus capitis; biochemistry; diagnostic techniques; genes; humans; ivermectin; lice; louse control; people; pesticides; physiology; resistance management
Abstract:
... Human lice represent one of the longest ectoparasitic relationships associated with mankind. Whereas the body louse vectors bacterial diseases that have killed millions, the head louse does not but represents an economic and social concern worldwide. A crisis exists in the control of lice due to the availability of only a few new pediculicides and the occurrence of resistance. In this review, we s ...
DOI:
10.1016/j.pestbp.2013.03.008

4. Indoxacarb, metaflumizone, and other sodium channel inhibitor insecticides: Mechanism and site of action on mammalian voltage-gated sodium channels

Author:
Richard T. von Stein; Kristopher S. Silver; David M. Soderlund
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 101-112
ISSN:
0048-3575
Subject:
Xenopus laevis; anticonvulsants; indoxacarb; local anesthetics; mammals; mechanism of action; metaflumizone; oocytes; pain; site-directed mutagenesis; sodium channels
Abstract:
... Sodium channel inhibitor (SCI) insecticides were discovered almost four decades ago but have only recently yielded important commercial products (e.g., indoxacarb and metaflumizone). SCI insecticides inhibit sodium channel function by binding selectively to slow-inactivated (non-conducting) sodium channel states. Characterization of the action of SCI insecticides on mammalian sodium channels using ...
DOI:
10.1016/j.pestbp.2013.03.004
PubMed:
24072940
PubMed Central:
PMC3780446

5. Mini review: Mode of action of mosquito repellents

Author:
Joseph C. Dickens; Jonathan D. Bohbot
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 149-155
ISSN:
0048-3575
Subject:
biochemistry; insect repellents; mechanism of action; pesticides; physiology
Abstract:
... The mode of action of mosquito repellents remains a controversial topic. However, electrophysiological studies and molecular approaches have provided a better understanding of how repellents exert their effects. Here, we briefly discuss various theories of repellent action and present the current status of knowledge of the effects of repellents on olfactory and gustatory processes. These findings ...
DOI:
10.1016/j.pestbp.2013.02.006

6. Acetylcholinesterase of Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi: Gene identification, expression, and biochemical properties of recombinant proteins

Author:
Kevin B. Temeyer; Pia U. Olafson; Danett K. Brake; Alexander P. Tuckow; Andrew Y. Li; Adalberto A. Pérez de León
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 118-123
ISSN:
0048-3575
Subject:
ticks; acetylcholinesterase; babesiosis; humans; Rhipicephalus microplus; Phlebotomus papatasi; cattle; metabolic detoxification; anaplasmosis; leishmaniasis; gene silencing; mutation; recombinant proteins; acaricides; genes
Abstract:
... The southern cattle tick Rhipicephalus (Boophilus) microplus (Bm) is a vector of bovine babesiosis and anaplasmosis. Tick resistance to organophosphate (OP) acaricide involves acetylcholinesterase (AChE) insensitivity to OP and metabolic detoxification. Sequencing and in vitro expression of Bm genes encoding AChE allowed biochemical characterization of three BmAChEs expressed in tick synganglion. ...
DOI:
10.1016/j.pestbp.2013.01.005

7. Diversity and convergence of sodium channel mutations involved in resistance to pyrethroids

Author:
Frank D. Rinkevich; Yuzhe Du; Ke Dong
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 93-100
ISSN:
0048-3575
Subject:
arthropod pests; disease vectors; genetic markers; human health; monitoring; mutation; nervous system; physiology; pyrethrins; pyrethroid insecticides; sodium channels
Abstract:
... Pyrethroid insecticides target voltage-gated sodium channels, which are critical for electrical signaling in the nervous system. The intensive use of pyrethroids in controlling arthropod pests and disease vectors has led to many instances of pyrethroid resistance around the globe. In the past two decades, studies have identified a large number of sodium channel mutations that are associated with r ...
DOI:
10.1016/j.pestbp.2013.02.007
PubMed:
24019556
PubMed Central:
PMC3765034

8. Effects of anticholinesterases on catalysis and induced conformational change of the peripheral anionic site of murine acetylcholinesterase

Author:
Fan Tong; Rafique M. Islam; Paul R. Carlier; Ming Ma; Fredrik Ekström; Jeffrey R. Bloomquist
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 79-84
ISSN:
0048-3575
Subject:
acetylcholinesterase; catalytic activity; enzyme inhibition; ethidium; fluorescence; inhibitory concentration 50; insecticides; insects; mice; pest control; pests; physiology; propidium
Abstract:
... Conventional insecticides targeting acetylcholinesterase (AChE) typically show high mammalian toxicities and because there is resistance to these compounds in many insect species, alternatives to established AChE inhibitors used for pest control are needed. Here we used a fluorescence method to monitor interactions between various AChE inhibitors and the AChE peripheral anionic site, which is a no ...
DOI:
10.1016/j.pestbp.2013.04.001
PubMed:
24003261
PubMed Central:
PMC3758491

9. In silico screening for compounds that match the pharmacophore of omega-hexatoxin-Hv1a leads to discovery and optimization of a novel class of insecticides

Author:
H. William Tedford; Bruce A. Steinbaugh; Lin Bao; Bradley D. Tait; Anna Tempczyk-Russell; Whitney Smith; Gary L. Benzon; Chad A. Finkenbinder; Robert M. Kennedy
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 124-140
ISSN:
0048-3575
Subject:
venoms; triazines; insecticides; neurons; calcium channels; Spodoptera exigua; calcium; mutagenesis; models; Aedes aegypti; pharmacology; insect larvae; screening; insects; databases; Blattodea
Abstract:
... Previously, scanning mutagenesis studies of the insecticidal peptide omega-hexatoxin-Hv1a identified a set of structural features used by the omega-hexatoxin-1 family to modulate insect calcium channels. These structural features were re-purposed as a 3D search term (i.e., a pharmacophore model) for mining commercially available compound databases, and screening of 1370 of the resultant candidate ...
DOI:
10.1016/j.pestbp.2013.01.009

10. Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi

Author:
Daniel R. Swale; Fan Tong; Kevin B. Temeyer; Andrew Li; Polo C-H. Lam; Maxim M. Totrov; Paul R. Carlier; Adalberto A. Pérez de León; Jeffrey R. Bloomquist
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 85-92
ISSN:
0048-3575
Subject:
ticks; acetylcholinesterase; disease vectors; lethal dose 50; humans; Rhipicephalus microplus; Phlebotomus papatasi; cattle; models; mutation; physiology; tryptophan; mice; pharmacology; vector control; Anopheles gambiae; active sites; malaria; pesticides
Abstract:
... The cattle tick, Rhipicephalus (Boophilus) microplus (Bm), and the sand fly, Phlebotomus papatasi (Pp), are disease vectors to cattle and humans, respectively. The purpose of this study was to characterize the inhibitor profile of acetylcholinesterases from Bm (BmAChE1) and Pp (PpAChE) compared to human and bovine AChE, in order to identify divergent pharmacology that might lead to selective inhib ...
DOI:
10.1016/j.pestbp.2013.03.005
PubMed:
24187393
PubMed Central:
PMC3811934

11. Insecticide-treated rodent baits for sand fly control

Author:
T.M. Mascari; R.W. Stout; J.W. Clark; S.W. Gordon; J.D. Bast; L.D. Foil
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 113-117
ISSN:
0048-3575
Subject:
Leishmania major; Phlebotomus duboscqi; adults; baiting; baits; blood; females; field experimentation; fluorescence; insecticidal properties; insecticides; ivermectin; parasites; pesticide application; rodents; Kenya
Abstract:
... Rodent baits containing systemic insecticides are potential tools to interrupt the cycle of transmission of Leishmania parasites by killing sand flies that take bloodmeals from rodents as adults. Bio-indicators that can be used in conjunction with rodent-targeted sand fly control methods also have been developed to demonstrate that the insecticide treatments are reaching the targeted life stages o ...
DOI:
10.1016/j.pestbp.2013.04.006

12. Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides

Author:
Catherine A. Hill; Jason M. Meyer; Karin F.K. Ejendal; Diego F. Echeverry; Emma G. Lang; Larisa V. Avramova; Jason M. Conley; Val J. Watts
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 141-148
ISSN:
0048-3575
Subject:
Aedes aegypti; Anopheles gambiae; Culex quinquefasciatus; Ixodes scapularis; agonists; antagonists; dopamine receptors; insect control; insecticides; larvae; mortality; screening; ticks; toxicity; vector control; vertebrates
Abstract:
... G protein-coupled receptors (GPCRs) comprise a large family of membrane-bound molecules that mediate critical physiological roles in both vertebrates and invertebrates. GPCRs are widely exploited targets of the pharmaceutical industry; approximately 50% of human drugs interact with these receptors. GPCRs are also candidate targets for next-generation insecticides and provide opportunities to disco ...
DOI:
10.1016/j.pestbp.2013.02.008

13. Robust cuticular penetration resistance in the common bed bug (Cimex lectularius L.) correlates with increased steady-state transcript levels of CPR-type cuticle protein genes

Author:
Reina Koganemaru; Dini M. Miller; Zach N. Adelman
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 190-197
ISSN:
0048-3575
Subject:
Cimex lectularius; amino acid composition; biochemistry; consensus sequence; gene expression regulation; genes; insecticide resistance; oxidation; physiology; proteome; pyrethroid insecticides; quantitative polymerase chain reaction; resistance to penetration; site-directed mutagenesis; transcriptome
Abstract:
... Bed bug (Cimex lectularius L.) populations are increasing worldwide, with resistance to insecticides thought to be a major contributor. Several recent reports have documented widespread kdr-type mutations at the target site for pyrethroid insecticides, and there is substantial published evidence for metabolic resistance mediated through cytochrome P450-mediated oxidation. Here we report that resis ...
DOI:
10.1016/j.pestbp.2013.01.001

14. The bed bug problem: Past, present, and future control methods

Author:
Reina Koganemaru; Dini M. Miller
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 177-189
ISSN:
0048-3575
Subject:
ABC transporters; Cimicidae; DDT (pesticide); caves; cleaning; cooperative research; dust formulations; ectoparasites; fumigation; humans; insecticide resistance; integrated pest management; malathion; physiology; powders; pyrethroid insecticides
Abstract:
... Bed bugs are wingless hematophagous ectoparasites that have co-existed with humans since they first appeared in the caves of Mediterranean and Middle Eastern regions approximately 65 million years ago. Bed bugs are not known to transmit diseases, most probably due to the lack of sylvatic cycles. Historical control methods include some remedies, but also many useful control methods such as communit ...
DOI:
10.1016/j.pestbp.2013.05.005

15. The genomics of human lice: From the genome to the potential for future control strategies

Author:
B.R. Pittendrigh; B.P. Olds; K.S. Yoon; S.H. Lee; W. Sun; J.M. Clark
Source:
Pesticide biochemistry and physiology 2013 v.106 no.3 pp. 172-176
ISSN:
0048-3575
Subject:
Pediculus humanus capitis; RNA interference; bacterial infections; biochemistry; genome; genomics; human diseases; human population; humans; hygiene; insect control; insects; lice; pesticide resistance; pesticides; physiology
Abstract:
... Human lice represent a unique ectoparasitic relationship with humans. Head lice, which do not vector human diseases, exist in many human populations where they represent a considerable nuisance. However, body lice tend to appear when social economic conditions that allow opportunities for significantly reduced hygiene in individuals or populations and they vector human bacterial diseases. There ar ...
DOI:
10.1016/j.pestbp.2013.03.010