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- Author:
- Abbasi-Maleki, Saeid; Maleki, Seyyed Gholamreza
- Source:
- PharmaNutrition 2021 v.15 pp. 100241
- ISSN:
- 2213-4344
- Subject:
- Foeniculum vulgare; albino; antidepressants; essential oils; fennel; fluoxetine; forced swimming test; haloperidol; locomotion; yohimbine
- Abstract:
- ... Fennel (Foeniculum vulgare) is widely used in food and pharmaceutical industries. Animal models also showed the antidepressant-like effect of the methanolic extract of fennel. Accordingly, the antidepressant potential of Foeniculum vulgare essential oil (FVEO) and the contribution of monoaminergic systems to this effect were evaluated in mice using the forced swim test (FST).The albino mice (22−27 ...
- DOI:
- 10.1016/j.phanu.2020.100241
-
https://dx.doi.org/10.1016/j.phanu.2020.100241
- Author:
- Shatylo, Valerii; Antoniuk-Shcheglova, Ivanna; Naskalova, Svitlana; Bondarenko, Olena; Havalko, Anna; Krasnienkov, Dmytro; Zabuga, Oksana; Kukharskyy, Vitaliy; Guryanov, Vitaly; Vaiserman, Alexander
- Source:
- PharmaNutrition 2021 v.15 pp. 100250
- ISSN:
- 2213-4344
- Subject:
- blood serum; body mass index; body weight; cholesterol metabolism; clinical trials; diastolic blood pressure; elderly; glucose; glucose tolerance tests; glutathione; insulin; low density lipoprotein cholesterol; metabolic syndrome; oxidative stress; placebos; quercetin; systolic blood pressure; telomeres
- Abstract:
- ... Quercetin is regarded as a promising phytochemical in treating metabolic syndrome (MetS).Present study is a randomized, placebo-controlled, double-blind clinical trial aimed at evaluating effects of quercetin on different aspects of MetS in patients aged 60 + . Study participants consumed two quercetin-containing or placebo tablets 3 times per day (daily dose = 240 mg) during 3 months.Quercetin ad ...
- DOI:
- 10.1016/j.phanu.2020.100250
-
https://dx.doi.org/10.1016/j.phanu.2020.100250
- Author:
- Hosseini, Sare; Rezaei, Sina; Moghaddam, Mohammad Reza Niazi; Elyasi, Sepideh; Karimi, Gholamreza
- Source:
- PharmaNutrition 2021 v.15 pp. 100253
- ISSN:
- 2213-4344
- Subject:
- anti-inflammatory activity; bioavailability; clinical trials; head; head and neck neoplasms; medicine; neck; placebos; radiotherapy; silymarin
- Abstract:
- ... Most of the patients with head and neck cancer who undergo radiotherapy experience some degrees of mucositis. Silymarin is a polyphenolic flavonoid that exhibits strong anti-inflammatory activity but has low oral bioavailability. In this research, we evaluated the effect of nano-formulation of silymarin on prevention of radiotherapy induced mucositis in patients with head and neck cancer.Thirty-on ...
- DOI:
- 10.1016/j.phanu.2021.100253
-
https://dx.doi.org/10.1016/j.phanu.2021.100253
- Author:
- Kohut, Magdalena; Lohne, Oswin; Leker, Jens; Bröring, Stefanie
- Source:
- PharmaNutrition 2021 v.15 pp. 100243
- ISSN:
- 2213-4344
- Subject:
- applied research; cosmetics; databases; drugs; industry; markets; nutrition; probiotics
- Abstract:
- ... The convergence of formerly distinct industries has been observed across a number of sectors including telecommunications, biopharma or nutrition. Its transformative character challenges incumbent market and industry structures by changing the way customers perceive products and technologies, forcing companies to restructure their offerings or even reshaping entire industry landscapes. Yet while t ...
- DOI:
- 10.1016/j.phanu.2020.100243
-
https://dx.doi.org/10.1016/j.phanu.2020.100243
- Author:
- Del Fabbro, Lucian; de Gomes, Marcelo Gomes; Goes, André Rossito; Jesse, Cristiano Ricardo
- Source:
- PharmaNutrition 2021 v.15 pp. 100242
- ISSN:
- 2213-4344
- Subject:
- autoimmune diseases; bioactive compounds; central nervous system; chrysin; dietary supplements; encephalitis; gene expression; glycoproteins; histology; microRNA; models; myelin sheath; oligodendroglia; peptides; sclerosis; therapeutics; transcription (genetics)
- Abstract:
- ... Multiple sclerosis (MS) is a chronic autoimmune disease which causing demyelination, resulting in several damages to central nervous system. NonCoding microRNAs (miRNAs) are post transcriptional gene expression regulators that have been associated with MS-pathophysiology. In this context, chrysin is a bioactive compound that has several pharmacological, nutraceutical and neuroprotective effects. T ...
- DOI:
- 10.1016/j.phanu.2020.100242
-
https://dx.doi.org/10.1016/j.phanu.2020.100242
- Author:
- Dhillon, Parvirti; Kaur, Ishtdeep; Singh, Kuljit
- Source:
- PharmaNutrition 2021 v.15 pp. 100251
- ISSN:
- 2213-4344
- Subject:
- dietary supplements; drug therapy; fetus; hypertension; morbidity; pregnancy; risk
- Abstract:
- ... Pregnant women body undergoes significant hormonal and metabolic alterations, to accumulate a growing fetus. These variations during the three trimesters can lead to the manifestation and development of various disease conditions. Among them, hypertensive disorders during pregnancy are one of the major causes of adverse maternal and neonatal outcomes including morbidity and mortality.We have searc ...
- DOI:
- 10.1016/j.phanu.2021.100251
-
https://dx.doi.org/10.1016/j.phanu.2021.100251
- Author:
- Sirotkin, Alexander V.; Pelleova, Betina; Fabova, Zuzana; Makovicky, Pavol; Alwasel, Saleh; Harrath, Abdel Halim
- Source:
- PharmaNutrition 2021 v.15 pp. 100247
- ISSN:
- 2213-4344
- Subject:
- apoptosis; bioflavonoids; caspase-3; cell viability; cyclins; estradiol; immunocytochemistry; isoflavones; metabolites; progesterone; rutin; steroidogenesis; swine; testosterone
- Abstract:
- ... The influence of plant isoflavone rutin (vitamin P) on healthy ovarian cells is unknown.We evaluated the effect of FSH alone, at various dose levels (0, 10, 100, or 1000 ng/mL), and in combination with rutin (10 μg/mL) on the markers of viability (trypan blue test), proliferation (expression of proliferating cell nuclear antigen, PCNA and cyclin B1), apoptosis (expression of Bcl-2-associated X pro ...
- DOI:
- 10.1016/j.phanu.2020.100247
-
https://dx.doi.org/10.1016/j.phanu.2020.100247
- Author:
- Parmenter, Benjamin Haddon; Bumrungpert, Akkarach; Thouas, George Anthony
- Source:
- PharmaNutrition 2021 v.15 pp. 100237
- ISSN:
- 2213-4344
- Subject:
- cognition; cross-sectional studies; fatty acids; females; income; musculoskeletal system; quality of life; China; Thailand; Vietnam
- Abstract:
- ... Limited studies have reported on socio-demographic factors, beliefs and health perceptions related to ω-3 supplement use in Asia. We aimed to examine characteristics associated with use of an ω-3 supplement in Asia.Adults residing in Thailand, China and Vietnam (n = 904; mean ± SD age, 31.3 ± 9.1 years; sex, 70.4 % female; education, 65.3 % to tertiary level) completed a cross-sectional survey, wi ...
- DOI:
- 10.1016/j.phanu.2020.100237
-
https://dx.doi.org/10.1016/j.phanu.2020.100237