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Pharmaceutical biology
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- Author:
- Irshad Ali; Zahid Manzoor; Jung-Eun Koo; Jung-Eun Kim; Sang-Hee Byeon; Eun-Sook Yoo; Hee-Kyoung Kang; Jin-Won Hyun; Nam-Ho Lee; Young-Sang Koh
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 435-440
- ISSN:
- 1744-5116
- Subject:
- DNA; IKappaB kinase; Ulva; Western blotting; anti-inflammatory activity; bioactive compounds; carotenoids; dendritic cells; enzyme-linked immunosorbent assay; human health; inflammation; inhibitory concentration 50; interleukin-12; interleukin-6; luciferase; macroalgae; mitogen-activated protein kinase; phosphorylation; phycocyanin; polyphenols; polysaccharides; reporter genes; transcription (genetics); transcription factor NF-kappa B; tumor necrosis factor-alpha; vitamins
- Abstract:
- ... Context: Seaweeds are rich in bioactive compounds in the form of vitamins, phycobilins, polyphenols, carotenoids, phycocyanins and polysaccharides; many of these are known to have advantageous applications in human health. 3-Hydroxy-4,7-megastigmadien-9-one (comp) was isolated from Ulva pertusa (U. pertusa) Kjellman (Ulvaceae), which is a familiar edible green seaweed. Objective: This study evalua ...
- DOI:
- 10.1080/13880209.2016.1246574
- PubMed:
- 27937044
- PubMed Central:
- PMC6130523
- https://doi.org/10.1080/13880209.2016.1246574
- Author:
- Rong Tang; Ru-hua Tian; Jia-zhong Cai; Jun-hui Wu; Xiao-ling Shen; Ying-jie Hu
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1740-1746
- ISSN:
- 1744-5116
- Subject:
- Cajanus cajan; acute toxicity; butanol; epididymis; ethanol; females; flavonoids; fractionation; hematology; high performance liquid chromatography; histopathology; kidneys; laboratory animals; leaf extracts; leaves; males; mice; mortality; oral administration; rats; stilbenes; testes; toxicity testing
- Abstract:
- ... Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts. Materials and methods: The leaves were extracted by water or 90% ethanol to obtain water or ethanol extract (WEC or EEC). EEC was suspended in water and successively fractionated into dichl ...
- DOI:
- 10.1080/13880209.2017.1309556
- PubMed:
- 28494681
- PubMed Central:
- PMC6130582
- https://doi.org/10.1080/13880209.2017.1309556
- Author:
- Jai Malik; Maninder Karan; Rachna Dogra
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 980-990
- ISSN:
- 1744-5116
- Subject:
- 3-nitropropionic acid; Celastrus paniculatus; antioxidant activity; body weight; brain; butanol; cognition; cortex; densitometry; ethanol; ethyl acetate; gait; herbal medicines; laboratory animals; linoleic acid; locomotion; males; medicinal properties; memory; nervous system diseases; neurons; oxidative stress; petroleum; plant extracts; protective effect; rats; seeds; thin layer chromatography
- Abstract:
- ... Context: Celastrus paniculatus Wild. (Celasteraceae) (CP) is a well-known Ayurvedic ‘Medhya Rasayana’ (nervine tonic), used extensively as a neuro-protective and memory enhancer, and in different central nervous system disorders. Objective: To evaluate the effect of CP against 3-nitropropionic acid (3-NP) induced Huntington's disease (HD) like symptoms in Wistar male rats. Materials and methods: T ...
- DOI:
- 10.1080/13880209.2017.1285945
- PubMed:
- 28164735
- PubMed Central:
- PMC6130694
- https://doi.org/10.1080/13880209.2017.1285945
- Author:
- Suranjana Nandi; Bidisha Ukil; Saptarshi Roy; Suman Kundu; Larisha Mawkhlieng Lyndem
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1401-1406
- ISSN:
- 1744-5116
- Subject:
- Clerodendrum; Raillietina; Verbenaceae; death; drug therapy; electron microscopy; histology; in vitro studies; leaf extracts; organelles; pH; paralysis; permeability; phytochemicals; praziquantel; shrubs; tapeworms; India
- Abstract:
- ... Context: Clerodendrum viscosum Vent. (Verbenaceae) is a shrub, widely used amongst the natives of India against various diseases. Objective: Crude extract of the plant was tested in vitro on a tapeworm Raillietina tetragona Molin (Davaineidae) to evaluate its potential anthelmintic efficacy and ultrastructural changes in the parasite. Materials and methods: Parasites were exposed to different conc ...
- DOI:
- 10.1080/13880209.2016.1226367
- PubMed:
- 27595160
- PubMed Central:
- PMC6130479
- https://doi.org/10.1080/13880209.2016.1226367
- Author:
- Laure Brigitte Kouitcheu Mabeku; Blandine Nanfack Nana; Bertrand Eyoum Bille; Roland Tchuenteu Tchuenguem; Eveline Nguepi
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 929-936
- ISSN:
- 1744-5116
- Subject:
- Aframomum; Helicobacter pylori; adverse effects; anti-ulcer activity; etiological agents; gastritis; humans; indomethacin; methanol; minimum inhibitory concentration; mucus; nitric oxide; nonsteroidal anti-inflammatory agents; oral administration; plant extracts; rats; seeds; stomach ulcers
- Abstract:
- ... Context: Peptic ulcer is one of the most common diseases affecting mankind. Although there are many products used for its treatment, most of these products produce severe adverse reactions requiring the search for novel compounds. Some Afromomum species are used traditionally to cure acute gastritis. Objective: To evaluate the antiulcer activity of the methanol extract of Aframomum pruinosum Gagne ...
- DOI:
- 10.1080/13880209.2017.1285326
- PubMed:
- 28164737
- PubMed Central:
- PMC6130624
- https://doi.org/10.1080/13880209.2017.1285326
- Author:
- Lucky Legbosi Nwidu; Ekramy Elmorsy; Jack Thornton; Buddhika Wijamunige; Anusha Wijesekara; Rebecca Tarbox; Averil Warren; Wayne Grant Carter
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1875-1883
- ISSN:
- 1744-5116
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Alzheimer disease; Carpolobia lutea; acetylcholinesterase; antioxidant activity; chloroform; cytotoxicity; dose response; ethanol; ethyl acetate; free radical scavengers; gallic acid; hepatocytes; hexane; humans; inhibitory concentration 50; leaves; methanol; oils; quercetin; roots; solvents; stems
- Abstract:
- ... Context: There is an unmet need to discover new treatments for Alzheimer’s disease. This study determined the anti-acetylcholinesterase (AChE) activity, DPPH free radical scavenging and antioxidant properties of Carpolobia lutea G. Don (Polygalaceae). Objective: The objective of this study is to quantify C. lutea anti-AChE, DPPH free radical scavenging, and antioxidant activities and cell cytotoxi ...
- DOI:
- 10.1080/13880209.2017.1339283
- PubMed:
- 28629287
- PubMed Central:
- PMC6130458
- https://doi.org/10.1080/13880209.2017.1339283
- Author:
- Thamizhiniyan Venkatesan; Eun-Jin Park; Young-Woong Choi; Jennifer Lee; Young-Kyoon Kim
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 837-846
- ISSN:
- 1744-5116
- Subject:
- Ternstroemia gymnanthera; anti-inflammatory activity; antioxidant activity; ascorbic acid; bark; bark extracts; cytotoxicity; enzyme-linked immunosorbent assay; flow cytometry; fluorescent antibody technique; gene expression; immunoblotting; inducible nitric oxide synthase; inflammation; interleukin-1beta; interleukin-6; macrophages; messenger RNA; mice; mitogen-activated protein kinase; nitric oxide; quantitative polymerase chain reaction; therapeutics; toxicity testing; transcription factor NF-kappa B; tumor necrosis factor-alpha; viability
- Abstract:
- ... Context: Ternstroemia gymnanthera Sprague (Theaceae) possesses various known pharmacological properties. However, its anti-inflammatory activity has not been reported. Objective: The anti-inflammatory activity of Ternstroemia gymnanthera stem bark aqueous extract (TGSBE) was evaluated using LPS-stimulated RAW264.7 macrophages. Materials and methods: Cytotoxicity was assessed by MTT assay after 24 ...
- DOI:
- 10.1080/13880209.2017.1278778
- PubMed:
- 28140744
- PubMed Central:
- PMC6130460
- https://doi.org/10.1080/13880209.2017.1278778
- Author:
- Samar S. Azab; Gehad A. Abdel Jaleel; Omayma A. Eldahshan
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1654-1661
- ISSN:
- 1744-5116
- Subject:
- Cinnamomum; alpha-pinene; alpha-terpineol; anti-inflammatory activity; bark; blood serum; cineole; edema; essential oils; ethanol; gas chromatography-mass spectrometry; gastritis; inflammation; leaves; lipid peroxidation; models; nitrates; nitric oxide; oils; oxidative stress; rats; sabinene; stomach; Egypt
- Abstract:
- ... Context: Nothing could be found in the literature concerning Cinnamomum glanduliferum (Wall) Meissn (Lauraceae) bark (CG) in Egypt. Objective: To investigate CG volatile oil chemically and its anti-inflammatory and gastroprotective effects. Materials and methods: Essential oils were investigated by GC-MS. Leaves oil was assessed at doses of 250, 500 and 1000 mg/kg for its anti-inflammatory effect ...
- DOI:
- 10.1080/13880209.2017.1314512
- PubMed:
- 28447506
- PubMed Central:
- PMC7011983
- https://doi.org/10.1080/13880209.2017.1314512
- Author:
- Hoang Le Tuan Anh; Dong-Cheol Kim; Wonmin Ko; Tran Minh Ha; Nguyen Xuan Nhiem; Pham Hai Yen; Bui Huu Tai; Luu Hong Truong; Vu Ngoc Long; Tran Gioi; Tran Hong Quang; Chau Van Minh; Hyuncheol Oh; Youn-Chul Kim; Phan Van Kiem
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1195-1201
- ISSN:
- 1744-5116
- Subject:
- Rutaceae; Western blotting; anti-inflammatory activity; chemical composition; coumarins; cytotoxicity; enzyme-linked immunosorbent assay; inducible nitric oxide synthase; inhibitory concentration 50; liver diseases; medicinal plants; neoplasms; nitric oxide; nitrites; protein synthesis; stems; therapeutics
- Abstract:
- ... Context: Paramignya trimera (Oliv.) Burkill (Rutaceae) has been used to treat liver diseases and cancer. However, the anti-inflammatory effects of this medicinal plant and its components have not been elucidated. Objective: This study investigated chemical constituents of the P. trimera stems and evaluated anti-inflammatory effects of isolated compounds. Materials and methods: Cytotoxicity of isol ...
- DOI:
- 10.1080/13880209.2017.1296001
- PubMed:
- 28245363
- PubMed Central:
- PMC6130569
- https://doi.org/10.1080/13880209.2017.1296001
- Author:
- Gyubyung Park; Eunji Kim; Young-Jin Son; Deok Hyo Yoon; Gi-Ho Sung; Adithan Aravinthan; Yung Chul Park; Jong-Hoon Kim; Jae Youl Cho
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 2074-2082
- ISSN:
- 1744-5116
- Subject:
- IKappaB kinase; Torilis japonica; anti-inflammatory activity; enzyme-linked immunosorbent assay; ethanol; fruits; gene overexpression; herbal medicines; immunoblotting; inducible nitric oxide synthase; inflammation; inhibitory concentration 50; lipopolysaccharides; macrophages; medicinal plants; medicine; nitric oxide; pesticides; phosphorylation; polymerase chain reaction; prostaglandin synthase; prostaglandins; reporter genes; transcription factor NF-kappa B
- Abstract:
- ... Context: Torilidis fructus, fruits of Torilis japonica Decadolle (Umbelliferae), is a medicinal herb traditionally used as a pesticide, an astrictive, or a medicine for various inflammatory diseases. Objectives: Due to the lack of pharmacological studies on this herbal medicine, we explored the inhibitory activity of torilidis fructus on the macrophage-mediated inflammatory response using its etha ...
- DOI:
- 10.1080/13880209.2017.1362011
- PubMed:
- 28832235
- PubMed Central:
- PMC6130681
- https://doi.org/10.1080/13880209.2017.1362011
- Author:
- Sun-Young Nam; Kyu-Yeob Kim; Mi Hye Kim; Jae-Bum Jang; So-Young Rah; Jin-Man Lee; Hyung-Min Kim; Hyun-Ja Jeong
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1856-1862
- ISSN:
- 1744-5116
- Subject:
- Western blotting; anti-inflammatory activity; enzyme-linked immunosorbent assay; high performance liquid chromatography; inducible nitric oxide synthase; inflammation; inhibitory concentration 50; interleukin-1beta; interleukin-6; lipopolysaccharides; macrophages; medicine; messenger RNA; mice; nitric oxide; prostaglandin synthase; prostatitis; reverse transcriptase polymerase chain reaction; secretion; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... Objective: To study the anti-inflammatory properties of OJ. Context: Ojayeonjonghwan (OJ) is a traditional Korean prescription, which has been widely used for the treatment of prostatitis. However, no scientific study has been performed of the anti-inflammatory effects of OJ. Materials and methods: Peritoneal macrophages were isolated 3–4 days after injecting a C57BL/6J mouse with thioglycollate. ...
- DOI:
- 10.1080/13880209.2017.1339282
- PubMed:
- 28614972
- PubMed Central:
- PMC6130514
- https://doi.org/10.1080/13880209.2017.1339282
- Author:
- Clarice P. Mudzengi; Amon Murwira; Musa Tivapasi; Chrispen Murungweni; Joan V. Burumu; Tinyiko Halimani
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1054-1060
- ISSN:
- 1744-5116
- Subject:
- Colophospermum mopane; Dichrostachys cinerea; Escherichia coli; Salvadora persica; Staphylococcus aureus; adverse effects; ampicillin; animal diseases; antibacterial properties; bacteria; bark; culture media; gentamicin; herbal medicines; leaves; livestock; methanol; minimum inhibitory concentration; plant extracts; roots
- Abstract:
- ... Context: Salvadora persica L. (Salvadoraceae), Colophospermum mopane (J.Kirk ex Benth.) J. Léonard (Leguminosae) and Dichrostachys cinerea (L.) Wight & Arn. (Leguminosae) crude extracts are used by local farmers against many livestock infections with little or no side effects usually associated with synthetic antimicrobials. However, their efficacy has rarely been tested. Objective: These plants w ...
- DOI:
- 10.1080/13880209.2017.1287744
- PubMed:
- 28187694
- PubMed Central:
- PMC6130738
- https://doi.org/10.1080/13880209.2017.1287744
- Author:
- Ricardo Nunes; Pawel Pasko; Malgorzata Tyszka-Czochara; Agnieszka Szewczyk; Marek Szlosarczyk; Isabel S. Carvalho
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 114-123
- ISSN:
- 1744-5116
- Subject:
- Bacillus cereus; Crataegus monogyna; Enterococcus faecalis; Equisetum telmateia; Escherichia coli; Geranium purpureum; Lavandula stoechas; Listeria monocytogenes; Mentha suaveolens; Pseudomonas aeruginosa; Staphylococcus aureus; aerial parts; antibacterial properties; antioxidant activity; antioxidants; ethanol; fibroblasts; herbs; high performance liquid chromatography; human cell lines; microorganisms; plant extracts; rosmarinic acid; solvents; voltammetry; zinc; Portugal
- Abstract:
- ... Context: Crataegus monogyna L. (Rosaceae) (CM), Equisetum telmateia L. (Equisataceae) (ET), Geranium purpureum Vil. (Geraniaceae) (GP), Mentha suaveolens Ehrh. (Lamiaceae) (MS), and Lavandula stoechas L. spp. luisieri (Lamiaceae) (LS) are all medicinal. Objective: To evaluate the antioxidant, antiproliferative and antimicrobial activities of plant extracts and quantify individual phenolics and zin ...
- DOI:
- 10.1080/13880209.2016.1230636
- PubMed:
- 27925492
- PubMed Central:
- PMC7011791
- https://doi.org/10.1080/13880209.2016.1230636
- Author:
- Chueh-Yu Lin; Yan-Shu Jhang; Shang-Chi Lai; En-Li Chen; I-Hsin Lin; Tung-Wu Chang; Yu-Wei Tseng; Vaishnavi Seenan; Jane Shiung; Ming-Hua Chen; Yun-Chen Chiang; Tsung-I Chen; Yin-Jeh Tzeng
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 2264-2269
- ISSN:
- 1744-5116
- Subject:
- Salvia miltiorrhiza; blood; blood glucose; forced swimming test; glycolysis; hypertrophy; lactic acid; malondialdehyde; mice; muscles; superoxide dismutase; swimming; urea nitrogen
- Abstract:
- ... Context: Tanshinone IIA (Tan IIA) is a constituent of Danshen Salvia miltiorrhiza Bunge (Lamiaceae); however, its antifatigue activity remains unclear. Objective: To study the antifatigue properties of Tan IIA and its underlying mechanisms. Materials and methods: In program I, three mouse groups were separately subjected to three gavages with 0, 1 and 6 mg/kg Tan IIA and forced swimming test (FST) ...
- DOI:
- 10.1080/13880209.2017.1401648
- PubMed:
- 29171356
- PubMed Central:
- PMC6130709
- https://doi.org/10.1080/13880209.2017.1401648
15. Antifungal and antioxidant activities of Coleonema album and C. pulchellum against skin diseases
- Author:
- Olufunke O. Fajinmi; Jiří Grúz; Petr Tarkowski; Manoj G. Kulkarni; Jeffrey F. Finnie; Johannes Van Staden
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1249-1255
- ISSN:
- 1744-5116
- Subject:
- Microsporum gypseum; Rutaceae; Trichophyton mentagrophytes; Trichophyton rubrum; antifungal properties; antioxidant activity; direct contact; essential oils; griseofulvin; ketoconazole; leaf extracts; methanol; minimum inhibitory concentration; mycelium; ointments; people; skin diseases; terpenoids; therapeutics; traditional medicine
- Abstract:
- ... Context: Coleonema album (Thunb) Bart. & H. L. Wendl (Rutaceae) has been used in the formulation of skincare products, and the Khoisan people rub it on their skin to add luster. Coleonema pulchellum I. Williams has received less attention in the South African traditional medicine. Objective: This study investigates the antifungal and antioxidant activities of C. album and C. pulchellum essential o ...
- DOI:
- 10.1080/13880209.2017.1296470
- PubMed:
- 28262031
- PubMed Central:
- PMC6130550
- https://doi.org/10.1080/13880209.2017.1296470
- Author:
- Mutiat Ibrahim; Nutan Kaushik; Abimbola Sowemimo; Hemraj Chhipa; Trevor Koekemoer; Maryna van de Venter; Olukemi A. Odukoya
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 590-595
- ISSN:
- 1744-5116
- Subject:
- Bignoniaceae; Botrytis cinerea; Fusarium oxysporum; Sclerotinia; Spodoptera litura; Syncephalastrum racemosum; Thanatephorus cucumeris; Trichoderma longibrachiatum; anti-inflammatory activity; antifeedants; antifeeding activity; antineoplastic activity; antioxidants; cell lines; endophytes; fungi; inhibitory concentration 50; insect larvae; leaves; methanol; neoplasm cells; neoplasms; poisoning; sequence analysis; solvents
- Abstract:
- ... Context: Plants harbor endophytes with potential bioactivity. Markhamia tomentosa (Benth) K. Schum ex. Engl. (Bignoniaceae) is reported to possess antioxidant, anti-inflammatory and anticancer activities. Objective: The antifungal and antiproliferative properties of endophytic fungi extracts and fractions from M. tomentosa were evaluated. Material and methods: Endophytic fungi were isolated from t ...
- DOI:
- 10.1080/13880209.2016.1263671
- PubMed:
- 27937112
- PubMed Central:
- PMC6130725
- https://doi.org/10.1080/13880209.2016.1263671
- Author:
- Jude E. Okokon; Bassey S. Antia; Dinesh Mohanakrishnan; Dinkar Sahal
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1394-1400
- ISSN:
- 1744-5116
- Subject:
- Plasmodium berghei; Plasmodium falciparum; Zea mays; antiplasmodial properties; cell lines; chloroquine; cytotoxicity; ethanol; ethyl acetate; hulls; inhibitory concentration 50; lethal dose 50; malaria; mice; models; parasites; traditional medicine; Nigeria
- Abstract:
- ... Context: Zea mays L. (Poacae) husk decoctions are traditionally used in the treatment of malaria by various tribes in Nigeria. Objective: To assess the antimalarial and antiplasmodial potentials of the husk extract and fractions on malaria parasites using in vivo and in vitro models. Materials and methods: The ethanol husk extract and fractions (187–748 mg/kg, p.o.) of Zea mays were investigated f ...
- DOI:
- 10.1080/13880209.2017.1302966
- PubMed:
- 28320254
- PubMed Central:
- PMC6130627
- https://doi.org/10.1080/13880209.2017.1302966
- Author:
- Jude E. Okokon; Nkemnele Bensella Augustine; Dinesh Mohanakrishnan
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1022-1031
- ISSN:
- 1744-5116
- Subject:
- Alchornea; Plasmodium berghei; Plasmodium falciparum; acute toxicity; analgesic effect; analgesics; animal diseases; anticarcinogenic activity; antiplasmodial properties; chloroquine; cytotoxicity; ethyl acetate; human cell lines; inhibitory concentration 50; lethal concentration 50; lethal dose 50; malaria; mice; models; pain; root extracts; traditional medicine; Nigeria
- Abstract:
- ... Context: Alchornea laxiflora (Benth.) Pax. & Hoffman (Euphorbiaceae) root decoctions are traditionally used in the treatment of malaria and pain in Nigeria. Objective: To assess the antimalarial, antiplasmodial and analgesic potentials of root extract and fractions against malarial infections and chemically-induced pains. Material and methods: The root extract and fractions of Alchornea laxiflora ...
- DOI:
- 10.1080/13880209.2017.1285947
- PubMed:
- 28183236
- PubMed Central:
- PMC6130711
- https://doi.org/10.1080/13880209.2017.1285947
19. Antimicrobial, anticancer, and antioxidant compounds from Premna resinosa growing in Saudi Arabia
- Author:
- Dina A. Albadawi; Ramzi A. Mothana; Jamal M. Khaled; Abdelkhader E. Ashour; Ashok Kumar; Sheikh F. Ahmad; Mansour S. Al-Said; Adnan J. Al-Rehaily; Nawal M. Almusayeib
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 1759-1766
- ISSN:
- 1744-5116
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Enterococcus faecalis; Gram-negative bacteria; Premna; Shigella flexneri; Staphylococcus aureus; aerial parts; antibacterial properties; antineoplastic activity; antioxidant activity; antioxidants; bronchitis; butanol; cytotoxicity; ethyl acetate; fractionation; hexane; human cell lines; human diseases; inhibitory concentration 50; kaempferol; lupeol; mechanism of action; methanol; methylene chloride; minimum inhibitory concentration; myricetin; neoplasm cells; neoplasms; plant extracts; quercetin; ribs; seizures; stigmasterol; Saudi Arabia
- Abstract:
- ... Context: Premna resinosa (Hochst.) Schauer (Lamiaceae) is used in many places to treat bronchitis, respiratory illness and convulsions of the rib cage. Objective: This study evaluates the anticancer, antimicrobial and antioxidant activities of P. resinosa, and isolates some responsible constituents. Materials and methods: The methanol extract of P. resinosa aerial parts and its fractions (n-hexane ...
- DOI:
- 10.1080/13880209.2017.1322617
- PubMed:
- 28508699
- PubMed Central:
- PMC6130449
- https://doi.org/10.1080/13880209.2017.1322617
- Author:
- Tiago Rodrigues Leite; Maria Arlene Pessoa da Silva; Antônio Carlito Bezerra dos Santos; Henrique Douglas Melo Coutinho; Antonia Eliene Duarte; José Galberto Martins da Costa
- Source:
- Pharmaceutical biology 2017 v.55 no.1 pp. 2015-2019
- ISSN:
- 1744-5116
- Subject:
- Candida albicans; Candida krusei; Candida tropicalis; Croton; Escherichia coli; Klebsiella pneumoniae; Pseudomonas aeruginosa; Staphylococcus aureus; alpha-pinene; amikacin; amphotericin B; antibacterial properties; antifungal properties; cedrol; chemical analysis; chemical constituents of plants; cineole; drugs; essential oils; gas chromatography-mass spectrometry; gentamicin; leaves; minimum inhibitory concentration; neomycin; nystatin; oils; pain; sales; spectrometers; synergism; Brazil
- Abstract:
- ... Context: Croton sp. are plants with a well-reported antimicrobial activity. Croton limae A.P. Gomes, M.F. Sales P.E. Berry (Euphorbiaceae), known as ‘marmeleiro-prateado’, is commonly used to manage abdominal pain in Brazil. Objective: This work evaluates the phytochemical composition, antimicrobial and modulatory activities of the essential oil of C. limae leaves (EOCL). Materials and methods: Th ...
- DOI:
- 10.1080/13880209.2017.1355926
- PubMed:
- 28738715
- PubMed Central:
- PMC6130731
- https://doi.org/10.1080/13880209.2017.1355926