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1. Semen hoveniae extract ameliorates alcohol-induced chronic liver damage in rats via modulation of the abnormalities of gut-liver axis

Author:
Qiu, Ping; Dong, Yu; Zhu, Tao; Luo, Yun-yun; Kang, Xian-jie; Pang, Min-xia; Li, Huan-zhou; Xu, Hao; Gu, Chao; Pan, Su-hua; Du, Wei-feng; Ge, Wei-hong
Source:
Phytomedicine 2019 v.52 pp. 40-50
ISSN:
0944-7113
Subject:
Hovenia dulcis; Toll-like receptor 4; Western blotting; alanine transaminase; aspartate transaminase; biomarkers; blood serum; dextrins; diet; endotoxins; eosin; ethanol; fatty liver; hepatoprotective effect; herbal medicines; histopathology; inflammation; intestines; laboratory animals; lipids; liver; maltose; microorganisms; occludins; rats; ribosomal RNA; sequence analysis; staining; therapeutics; transcription factor NF-kappa B; transmission electron microscopes; transmission electron microscopy; tumor necrosis factor-alpha
Abstract:
... hematoxylin and eosin (H&E) staining and Transmission electron microscope (TEM). The ...
DOI:
10.1016/j.phymed.2018.09.209

2. Anti-renal fibrosis effect of asperulosidic acid via TGF-β1/smad2/smad3 and NF-κB signaling pathways in a rat model of unilateral ureteral obstruction

Author:
Xianyuan, Lu; Wei, Zou; Yaqian, Dong; Dan, Zhou; Xueli, Tong; Zhanglu, Dong; Guanyi, Liang; Lan, Tang; Menghua, Liu
Source:
Phytomedicine 2019 v.53 pp. 274-285
ISSN:
0944-7113
Subject:
Western blotting; actin; animal models; anti-inflammatory activity; blood serum; chemokine CCL2; collagen; dose response; extracellular matrix; fibronectins; fibrosis; gene expression; immunohistochemistry; inflammation; interferon-gamma; interleukin-1beta; interleukin-6; iridoid glycosides; laboratory animals; messenger RNA; muscles; protective effect; protein content; quantitative polymerase chain reaction; rats; renal failure; renal function; signal transduction; staining; tissues; transcription factor NF-kappa B; transforming growth factor beta 1; tumor necrosis factor-alpha; urea nitrogen; uric acid; urine
Abstract:
... collected for pathological analysis (hematoxylin and eosion (H&E) staining and Masson's ...
DOI:
10.1016/j.phymed.2018.09.009

3. Altered metabolites in guinea pigs with allergic asthma after acupoint sticking therapy: New insights from a metabolomics approach

Author:
Xiang, Shi-jian; Li, Meng-heng; Chan, Chi-on; Shen, Qun; Chen, Si-bao; An, Bai-chao; Yuen, Ailsa Chui-ying; Wu, Wen-feng; Tang, Hok-him; Cao, Si-wei; Ruan, Shi-fa; Wang, Zhu-xian; Weng, Li-dong; Zhu, Hong-xia; Chen, Huo-ji; Wong, Melody Yee-Man; Zhang, Yan; Mok, Daniel Kam-wah; Liu, Qiang
Source:
Phytomedicine 2019 v.54 pp. 182-194
ISSN:
0944-7113
Subject:
Chinese people; Western blotting; amino acids; anti-inflammatory activity; aspartate transaminase; asthma; blood serum; collagen; enzyme-linked immunosorbent assay; eosin; epinephrine; gene expression; guinea pigs; histopathology; immunoglobulin E; inflammation; interleukin-13; interleukin-4; interleukin-5; lungs; mass spectrometry; messenger RNA; metabolism; metabolites; metabolomics; ovalbumin; phospholipids; phosphorylation; protective effect; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; sphingolipids; staining; therapeutics; transcription factor NF-kappa B; ultra-performance liquid chromatography
Abstract:
... Histopathological evaluation of the lung tissue was performed by hematoxylin and eosin (H&E) ...
DOI:
10.1016/j.phymed.2018.09.021

4. Rapid discovery of quality-markers from Kaixin San using chinmedomics analysis approach

Author:
Wang, Xi-jun; Zhang, Ai-hua; Kong, Ling; Yu, Jing-bo; Gao, Hong-lei; Liu, Zhi-dong; Sun, Hui
Source:
Phytomedicine 2019 v.54 pp. 371-381
ISSN:
0944-7113
Subject:
Alzheimer disease; Oriental traditional medicine; amino acid metabolism; animal models; biomarkers; blood serum; brain; cognition; computer software; elderly; histopathology; immunohistochemistry; lipid metabolism disorders; memory disorders; metabolomics; mice; necrosis; neurodegenerative diseases; neurons; staining; therapeutics; transgenic animals
Abstract:
... (MWM), immunohistochemistry detection of Aβ1-42, Hematoxylin-eosin staining (HE), ...
DOI:
10.1016/j.phymed.2017.12.014

5. Yu-Ping-Feng-San ameliorates recurrent allergic inflammation of atopic dermatitis by repairing tight junction defects of the epithelial barrier

Author:
Zheng, Jie; Wang, Xiaoyu; Tao, Yu; Wang, Yan; Yu, Xi; Liu, Hailiang; Ji, Lv; Bao, Kaifan; Wang, Can; Jia, Zhirong; Hong, Min
Source:
Phytomedicine 2019 v.54 pp. 214-223
ISSN:
0944-7113
Subject:
Western blotting; animal models; anti-allergic agents; atopic dermatitis; blood serum; cell culture; ears; electrical resistance; electron microscopy; enzyme-linked immunosorbent assay; eosin; epithelium; formononetin; immunoglobulin E; immunohistochemistry; inflammation; interferon-gamma; interleukin-13; interleukin-4; interleukin-5; isothiocyanates; liquid-air interface; mice; occludins; relapse; remission; staining; therapeutics; tight junctions
Abstract:
... analyses of ear tissue inflammation were evaluated by hematoxylin and eosin staining. ...
DOI:
10.1016/j.phymed.2018.09.190

6. Anti-ulcerogenic activity of dentatin from clausena excavata Burm.f. against ethanol-induced gastric ulcer in rats: Possible role of mucus and anti-oxidant effect

Author:
Sidahmed, Heyam Mohamed Ali; Vadivelu, Jamuna; Loke, Mun Fai; Arbab, Ismail Adam; Abdul, Bustamam; Sukari, Mohd Aspollah; Abdelwahab, Siddig Ibrahim
Source:
Phytomedicine 2019 v.55 pp. 31-39
ISSN:
0944-7113
Subject:
Clausena excavata; anti-ulcer activity; antioxidants; blood serum; eosin; ethanol; gastric acid; gastric mucosa; glutathione; heat-shock protein 70; immunohistochemistry; lipid peroxidation; malondialdehyde; models; mucus; prostaglandins; pylorus; rats; schiff bases; stomach ulcers; superoxide dismutase
Abstract:
... using Hematoxylin and eosin (HE), periodic acid Schiff base stainings and ...
DOI:
10.1016/j.phymed.2018.06.036

7. Combined delivery of curcumin and the heme oxygenase-1 gene using cholesterol-conjugated polyamidoamine for anti-inflammatory therapy in acute lung injury

Author:
Kim, Gyeungyun; Piao, Chunxian; Oh, Jungju; Lee, Minhyung
Source:
Phytomedicine 2019 v.56 pp. 165-174
ISSN:
0944-7113
Subject:
animal models; anti-inflammatory activity; curcumin; cytokines; enzyme-linked immunosorbent assay; eosin; epithelial cells; gels; gene transfer; genes; heme oxygenase (biliverdin-producing); heparin; immunohistochemistry; light scattering; luciferase; lungs; micelles; mortality; plasmids; respiratory tract diseases; therapeutics; transcription factor NF-kappa B
Abstract:
... immunohistochemistry, and hematoxylin and eosin staining.The pDNA/PamChol-Cur complex had a size of ...
DOI:
10.1016/j.phymed.2018.09.240

8. Neuroprotective effects of a Rhodiola crenulata extract on amyloid-β peptides (Aβ1-42) -induced cognitive deficits in rat models of Alzheimer's disease

Author:
Zhang, Xiaoxue; Wang, Xue; Hu, Xinhua; Chu, Xiaowen; Li, Xintong; Han, Fei
Source:
Phytomedicine 2019 v.57 pp. 331-338
ISSN:
0944-7113
Subject:
Alzheimer disease; Rhodiola crenulata; Western blotting; acetylcholine; acetyltransferases; animal models; antidepressants; choline; cognition; cognitive disorders; cortex; freeze drying; healthy diet; hippocampus; immunohistochemistry; malondialdehyde; medicine; memory; memory disorders; neurons; neuroprotective effect; oxidative stress; peptides; rats; staining; superoxide dismutase; swimming; tau-protein kinase; therapeutics; China
Abstract:
... of the rats. Subsequently, biochemical assays, hematoxylin-eosin staining, ...
DOI:
10.1016/j.phymed.2018.12.042

9. Periplocin promotes wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase

Author:
Chen, Lei; Jiang, Pan; Li, Jinsong; Xie, Zijian; Xu, Yunhui; Qu, Wei; Feng, Feng; Liu, Wenyuan
Source:
Phytomedicine 2019 v.57 pp. 72-83
ISSN:
0944-7113
Subject:
Western blotting; animal models; arthritis; cell movement; collagen; eosin; excision; fibroblasts; granulation tissue; histopathology; mechanism of action; mitogen-activated protein kinase; precipitin tests; rats; sodium-potassium-exchanging ATPase; staining; steroids; tissue repair
Abstract:
... models. Histopathology of the wounded skin on day 9 was studied via hematoxylin and ...
DOI:
10.1016/j.phymed.2018.12.015

10. Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression

Author:
Zhao, Xue-shan; Zheng, Bin; Wen, Ya; Sun, Yan; Wen, Jin-kun; Zhang, Xin-hua
Source:
Phytomedicine 2019 v.58 pp. 152754
ISSN:
0944-7113
Subject:
Salvia miltiorrhiza; Western blotting; cardioprotective effect; cardiovascular diseases; carotid arteries; cell cycle; cyclins; eosin; hyperplasia; phenotype; proliferating cell nuclear antigen; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; salvianolic acid; smooth muscle; staining; China
Abstract:
... hematoxylin/eosin staining. qRT-PCR was used to detect the expression of miR-146a, KLF5, cyclin ...
DOI:
10.1016/j.phymed.2018.11.014

11. Qishen Granule Attenuates Cardiac Fibrosis by Regulating TGF-β /Smad3 and GSK-3β Pathway

Author:
Zeng, Zifan; Wang, Qiyan; Yang, Xiaomin; Ren, Yinglu; Jiao, Shihong; Zhu, Qingqing; Guo, Dongqing; Xia, Kai; Wang, Yong; Li, Chun; Wang, Wei
Source:
Phytomedicine 2019 pp. 152949
ISSN:
0944-7113
Subject:
Western blotting; actin; cardiac output; cardioprotective effect; collagen; coronary vessels; echocardiography; extracellular matrix; fibroblasts; fibrosis; fluorescence; genes; glycogen synthase kinases; heart; heart failure; immunohistochemistry; in vitro studies; laboratory animals; males; models; muscles; phosphatidylinositol 3-kinase; phosphorylation; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; secretion; signal transduction; staining; surgery; transforming growth factor beta 1
Abstract:
... assessed by Hematoxylin-Eosin (HE), Masson's trichrome and Picrosirius red (PSR) ...
DOI:
10.1016/j.phymed.2019.152949

12. Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice

Author:
Liang, Guoyan; Nie, Yichu; Chang, Yunbing; Zeng, Shixing; Liang, Changxiang; Zheng, Xiaoqing; Xiao, Dan; Zhan, Shiqiang; Zheng, Qiujian
Source:
Phytomedicine 2019 v.59 pp. 152772
ISSN:
0944-7113
Subject:
Oriental traditional medicine; allopurinol; animal models; antioxidants; blood serum; calipers; creatinine; edema; gout; hyperplasia; hyperuricemia; interleukin-10; interleukin-12; interleukin-1beta; interleukin-6; kidneys; mice; oral administration; patients; potassium; protective effect; rhizomes; tandem mass spectrometry; taxifolin; tumor necrosis factor-alpha; urea nitrogen; uric acid; vacuoles
Abstract:
... with hematoxylin and eosin.Nine compounds in the RSG water extract were ...
DOI:
10.1016/j.phymed.2018.11.032

13. Danshen extract (Salvia miltiorrhiza Bunge) attenuate spinal cord injury in a rat model: A metabolomic approach for the mechanism study

Author:
Zhang, Qian; Liu, Xifang; Yan, Liang; Zhao, Rui; An, Jing; Liu, Ciucui; Yang, Hao
Source:
Phytomedicine 2019 v.62 pp. 152966
ISSN:
0944-7113
Subject:
Salvia miltiorrhiza; Western blotting; animal injuries; animal models; biochemical pathways; fluorescent antibody technique; histopathology; mechanism of action; medicinal plants; metabolites; metabolomics; nervous system diseases; neuroprotective effect; rats; rhizomes; roots; spinal cord; staining; tandem mass spectrometry; ultra-performance liquid chromatography
Abstract:
... score and hematoxylin-eosin staining, respectively. In addition, neurofilament 200 ...
DOI:
10.1016/j.phymed.2019.152966

14. Rubrofusarin-6-β-gentiobioside inhibits lipid accumulation and weight gain by regulating AMPK/mTOR signaling

Author:
Han, Yo-Han; Kee, Ji-Ye; Park, Seong-Hwan; Mun, Jeong-Geon; Jeon, Hee-Dong; Park, Jinbong; Zou, Qin-Peng; Liu, Xiang-Qian; Hong, Seung-Heon
Source:
Phytomedicine 2019 v.62 pp. 152952
ISSN:
0944-7113
Subject:
AMP-activated protein kinase; Western blotting; animal disease models; binding proteins; blood serum; eosin; epididymis; fatty liver; fluorescent antibody technique; high fat diet; humans; hyperlipidemia; in vitro studies; lipids; liver; mesenchymal stromal cells; mice; obesity; peroxisome proliferator-activated receptors; quantitative polymerase chain reaction; rapamycin; reverse transcriptase polymerase chain reaction; staining; therapeutics; weight gain; white adipose tissue
Abstract:
... effect of RFG was confirmed in HFD-induced mice model using hematoxylin and eosin ...
DOI:
10.1016/j.phymed.2019.152952